Publications "Hilbrig, Frank"

Article in a journal

Steiner, Thomas ; Möller, Julia N. ; Löder, Martin G. J. ; Hilbrig, Frank ; Laforsch, Christian ; Freitag, Ruth:
Microplastic Contamination of Composts and Liquid Fertilizers from Municipal Biowaste Treatment Plants : Effects of the Operating Conditions.
In: Waste and Biomass Valorization. Vol. 14 (2023) . - pp. 873-887.
ISSN 1877-265X
DOI: https://doi.org/10.1007/s12649-022-01870-2

Weithmann, Nicolas ; Mlinar, Stanislava ; Hilbrig, Frank ; Bachmaf, Samer ; Arndt, Julia ; Planer-Friedrich, Britta ; Weig, Alfons ; Freitag, Ruth:
Arsenic metabolism in technical biogas plants : possible consequences for resident microbiota and downstream units.
In: AMB Express. Vol. 9 (2019) . - 190.
ISSN 2191-0855
DOI: https://doi.org/10.1186/s13568-019-0902-6

Werner, Melanie ; Schmoldt, Daria ; Hilbrig, Frank ; Jérôme, Valérie ; Raup, Alexander ; Zambrano, Kenny ; Hübner, Holger ; Buchholz, Rainer ; Freitag, Ruth:
High Cell Density Cultivation of Human Leukemia T Cells (Jurkat Cells) in Semipermeable Polyelectrolyte Microcapsules.
In: Engineering in Life Sciences. Vol. 15 (2015) Issue 4 . - pp. 357-367.
ISSN 1618-2863
DOI: https://doi.org/10.1002/elsc.201400186

Werner, Melanie ; Biss, Karsten ; Jérôme, Valérie ; Hilbrig, Frank ; Freitag, Ruth ; Zambrano, Kenny ; Hübner, Holger ; Buchholz, Rainer ; Mahou, Redouan ; Wandrey, Christine:
Use of the mitochondria toxicity assay for quantifying the viable cell density of microencapsulated Jurkat cells.
In: Biotechnology Progress. Vol. 29 (2013) Issue 4 . - pp. 986-993.
ISSN 1520-6033
DOI: https://doi.org/10.1002/btpr.1734

Hilbrig, Frank ; Freitag, Ruth:
Isolation and purification of recombinant proteins, antibodies and plasmid DNA with hydroxyapatite chromatography.
In: Biotechnology Journal. Vol. 7 (2012) Issue 1 . - pp. 90-102.
ISSN 1860-7314
DOI: https://doi.org/10.1002/biot.201100015

Arnold, Marc ; Bittermann, Holger ; Kalbfuss-Zimmermann, Bernd ; Neumann, Thomas ; Schmidt, Kristina ; Sekul, Renate ; Hilbrig, Frank ; Ludolph, Heiko ; Freitag, Ruth:
Antibody purification by affinity chromatography based on small molecule affinity ligands identified by SPR-based screening of chemical microarrays.
In: Journal of Chromatography A. Vol. 1218 (2011) Issue 29 . - pp. 4649-4659.
ISSN 0021-9673
DOI: https://doi.org/10.1016/j.chroma.2011.05.040

Hofstetter, Eugen-Maria ; Gabler, Ralf ; Peiffer, Stefan ; Hilbrig, Frank ; Freitag, Ruth:
Ammoniakstrippung an einer etablierten, thermophilen Biogasanlage - technische und wirtschaftliche Evaluierung.
In: Chemie Ingenieur Technik. Vol. 81 (2009) Issue 7 . - pp. 921-932.
ISSN 1522-2640
DOI: https://doi.org/10.1002/cite.200900033

Hilbrig, Frank ; Jérôme, Valérie ; Salzig, Mark ; Freitag, Ruth:
Strategy for the isolation of native dehydrogenases with potential for biosensor development from the organism Hyphomicrobium zavarzinii ZV580.
In: Journal of Chromatography A. Vol. 1216 (2009) Issue 16 . - pp. 3518-3525.
ISSN 0021-9673
DOI: https://doi.org/10.1016/j.chroma.2008.09.020

Parisot, Judicaël ; Kurz, Katrin ; Hilbrig, Frank ; Freitag, Ruth:
Use of azobenzene amino acids as photo-responsive conformational switches to regulate antibody–antigen interaction.
In: Journal of Separation Science. Vol. 32 (2009) Issue 10 . - pp. 1613-1624.
ISSN 1615-9314
DOI: https://doi.org/10.1002/jssc.200800698

Achmann, Sabine ; Hermann, Markus ; Hilbrig, Frank ; Jérôme, Valérie ; Hämmerle, Martin ; Freitag, Ruth ; Moos, Ralf:
Direct detection of formaldehyde in air by a Novel NAD⁺- and glutathione-independent formaldehyde dehydrogenase-Based biosensor.
In: Talanta. Vol. 75 (2008) Issue 3 . - pp. 786-791.
ISSN 0039-9140
DOI: https://doi.org/10.1016/j.talanta.2007.12.015

Stocker-Majd, Gisela ; Hilbrig, Frank ; Freitag, Ruth:
Extraction of haemoglobin from human blood by affinity precipitation using a haptoglobin-based stimuli–responsive affinity macroligand.
In: Journal of Chromatography A. Vol. 1194 (2008) Issue 1 . - pp. 57-65.
ISSN 0021-9673
DOI: https://doi.org/10.1016/j.chroma.2008.03.091

Jérôme, Valérie ; Hermann, Markus ; Hilbrig, Frank:
A fast method for the quantification of methylamine in fermentation broths by gas chromatography.
In: Journal of Chromatography B. Vol. 861 (2008) Issue 1 . - pp. 88-94.
ISSN 1873-376X
DOI: https://doi.org/10.1016/j.jchromb.2007.11.027

Stocker, Gisela ; Dumoulin, Dorothée ; Vandevyver, Caroline ; Hilbrig, Frank ; Freitag, Ruth:
Screening of a human antibody phage display library against a peptide antigen using stimuli-responsive bioconjugates.
In: Biotechnology Progress. Vol. 24 (2008) Issue 6 . - pp. 1314-1324.
ISSN 1520-6033
DOI: https://doi.org/10.1002/btpr.60

Freitag, Ruth ; Schumacher, Ivo ; Hilbrig, Frank:
Affinity precipitation an option for early capture in bioprocessing.
In: Biotechnology Journal. Vol. 2 (2007) Issue 6 . - pp. 685-690.
ISSN 1860-7314
DOI: https://doi.org/10.1002/biot.200600200

Jérôme, Valérie ; Hermann, Markus ; Hilbrig, Frank ; Freitag, Ruth:
Development of a fed-batch process for the production of a dye-linked formaldehyde dehydrogenase in Hyphomicrobium zavarzinii ZV 580.
In: Applied Microbiology and Biotechnology. Vol. 77 (2007) Issue 4 . - pp. 779-788.
ISSN 1432-0614
DOI: https://doi.org/10.1007/s00253-007-1218-z

O'Mahony, Kevin ; Freitag, Ruth ; Hilbrig, Frank ; Schumacher, Ingo ; Müller, Patrick:
Integration of bacteria capture via filtration and in situ lysis for recovery of plasmid DNA under industry-compatible conditions.
In: Biotechnology Progress. Vol. 23 (2007) Issue 4 . - pp. 895-903.
ISSN 1520-6033
DOI: https://doi.org/10.1021/bp0701113

Freitag, Ruth ; Hilbrig, Frank:
Theory and practical understanding of the migration behavior of proteins and peptides in CE and related techniques.
In: Electrophoresis. Vol. 28 (2007) Issue 13 . - pp. 2125-2144.
ISSN 1522-2683
DOI: https://doi.org/10.1002/elps.200600792

O'Mahony, Kevin ; Freitag, Ruth ; Dhote, Bernhard ; Hilbrig, Frank ; Müller, Patrick ; Schumacher, Ivo:
Capture of Bacteria from Fermentation Broth by Body Feed Filtration : A Solved Problem?
In: Biotechnology Progress. Vol. 22 (2006) Issue 2 . - pp. 471-483.
ISSN 1520-6033
DOI: https://doi.org/10.1021/bp050302a

Pöhner, Claudia ; Hilbrig, Frank ; Jérôme, Valérie ; Freitag, Ruth:
Design and Characterization of Stimuli-Responsive FLAG-tag Analogues and the Illumination-Induced Modulation of Their Interaction with Antibody 4E11.
In: Biotechnology Progress. Vol. 22 (2006) Issue 4 . - pp. 1170-1178.
ISSN 1520-6033
DOI: https://doi.org/10.1021/bp060011h

Stocker, Gisela ; Vandevyver, Caroline ; Hilbrig, Frank ; Freitag, Ruth:
Purification of RT-PCR Competent Poly(A) mRNA from Crude Cell Lysate by Affinity Precipitation.
In: Biotechnology Progress. Vol. 22 (2006) Issue 6 . - pp. 1621-1629.
ISSN 1520-6033
DOI: https://doi.org/10.1021/bp060095u

O'Mahony, Kevin ; Freitag, Ruth ; Hilbrig, Frank ; Müller, Patrick ; Schumacher, Ivo:
Proposal for a better integration of bacterial lysis into the production of plasmid DNA at large scale.
In: Journal of Biotechnology. Vol. 119 (2005) Issue 2 . - pp. 118-132.
ISSN 1873-4863
DOI: https://doi.org/10.1016/j.jbiotec.2005.03.020

Hilbrig, Frank ; Freitag, Ruth:
Continuous annular chromatography.
In: Journal of Chromatography B. Vol. 790 (2003) Issue 1-2 . - pp. 1-15.
ISSN 1873-376X
DOI: https://doi.org/10.1016/S1570-0232(03)00085-0

Costioli, Matteo D. ; Fisch, Igor ; Garret-Flaudy, Frédéric ; Hilbrig, Frank ; Freitag, Ruth:
DNA purification by triple-helix affinity precipitation.
In: Biotechnology and Bioengineering. Vol. 81 (2003) Issue 5 . - pp. 535-545.
ISSN 1097-0290
DOI: https://doi.org/10.1002/bit.10497

Hilbrig, Frank ; Freitag, Ruth:
Protein purification by affinity precipitation.
In: Journal of Chromatography B. Vol. 790 (2003) Issue 1-2 . - pp. 79-90.
ISSN 1873-376X
DOI: https://doi.org/10.1016/S1570-0232(03)00081-3

Article in a book

Freitag, Ruth ; Hilbrig, Frank:
Use of the avidin (imino)biotin system as a general approach to affinity precipitation.
In: McMahon, Robert J. (ed.): Avidin-Biotin interactions : methods and applications. - Totowa, NJ : Humana Press , 2008 . - pp. 35-50 . - (Methods in Molecular Biology ; 418 )
ISBN 978-1-588-29583-5