Veröffentlichungen "Schweimer, Kristian"

2025

Lomoschitz, Andrea ; Meyer, Julia ; Guitart, Tanit ; Krepl, Miroslav ; Lapouge, Karine ; Hayn, Clara ; Schweimer, Kristian ; Simon, Bernd ; Šponer, Jiří ; Gebauer, Fátima ; Hennig, Janosch:
The Drosophila RNA binding protein Hrp48 binds a specific RNA sequence of the msl-2 mRNA 3' UTR to regulate translation.
In: Biophysical Chemistry. Bd. 316 (2025) . - 107346.
ISSN 1873-4200
DOI: https://doi.org/10.1016/j.bpc.2024.107346

2024

Schaller, Roman ; Schmidt, Marius ; Schweimer, Kristian ; Schmalz, Holger:
Patchy stereocomplex micelles as efficient compatibilizers for polymer blends.
In: Polymer Chemistry. Bd. 15 (2024) Heft 30 . - S. 3100-3112.
ISSN 1759-9954
DOI: https://doi.org/10.1039/D4PY00449C

2023

Adolph, Ramona S. ; Beck, Eileen ; Schweimer, Kristian ; Di Fonzo, Andrea ; Weyand, Michael ; Rösch, Paul ; Wöhrl, Birgitta M. ; Steegborn, Clemens:
Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein.
In: Life. Bd. 13 (2023) Heft 4 . - 949.
ISSN 2075-1729
DOI: https://doi.org/10.3390/life13040949

2022

Zuber, Philipp ; Daviter, Tina ; Heißmann, Ramona ; Persau, Ulrike ; Schweimer, Kristian ; Knauer, Stefan H.:
Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins.
In: eLife. Bd. 11 (2022) . - e76630.
ISSN 2050-084X
DOI: https://doi.org/10.7554/eLife.76630

Weiss, Sandra ; Adolph, Ramona S. ; Schweimer, Kristian ; DiFonzo, Andrea ; Meleshin, Marat ; Schutkowski, Mike ; Steegborn, Clemens:
Molecular Mechanism of Sirtuin 1 Modulation by the AROS Protein.
In: International Journal of Molecular Sciences. Bd. 23 (2022) Heft 21 . - 12764.
ISSN 1422-0067
DOI: https://doi.org/10.3390/ijms232112764

2021

Kröger, Pascal ; Shanmugaratnam, Sooruban ; Ferruz, Noelia ; Schweimer, Kristian ; Höcker, Birte:
A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
In: Structure. Bd. 29 (2021) Heft 5 . - S. 433-443.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2020.12.005

Dietler, Julia ; Schubert, Roman ; Krafft, Tobias G. A. ; Meiler, Simone ; Kainrath, Stephanie ; Richter, Florian ; Schweimer, Kristian ; Weyand, Michael ; Janovjak, Harald ; Möglich, Andreas:
A Light-Oxygen-Voltage Receptor Integrates Light and Temperature.
In: Journal of Molecular Biology. Bd. 433 (2021) Heft 15 . - 167107.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2021.167107

2020

Hartl, Frederike A. ; Beck-García, Esmeralda ; Woessner, Nadine M. ; Flachsmann, Lea J. ; Velasco Cárdenas, Rubí M.-H. ; Brandl, Simon M. ; Taromi, Sanaz ; Fiala, Gina J. ; Morath, Anna ; Mishra, Pankaj ; Yousefi, O. Sascha ; Zimmermann, Julia ; Hoefflin, Nico ; Köhn, Maja ; Wöhrl, Birgitta M. ; Zeiser, Robert ; Schweimer, Kristian ; Günther, Stefan ; Schamel, Wolfgang W. ; Minguet, Susana:
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
In: Nature Immunology. Bd. 21 (Juli 2020) . - S. 902-913.
ISSN 1529-2916
DOI: https://doi.org/10.1038/s41590-020-0732-3

Liess, Anna K. L. ; Kucerova, Alena ; Schweimer, Kristian ; Schlesinger, Dörte ; Dybkov, Olexandr ; Urlaub, Henning ; Mansfeld, Jörg ; Lorenz, Sonja:
Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
In: Science Signaling. Bd. 13 (2020) Heft 654 . - eaba8208.
ISSN 1937-9145
DOI: https://doi.org/10.1126/scisignal.aba8208

Dudenhöffer, Benjamin R. ; Borggräfe, Jan ; Schweimer, Kristian ; Knauer, Stefan H.:
NusA directly interacts with antitermination factor Q from phage λ.
In: Scientific Reports. Bd. 10 (2020) . - 6607.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-020-63523-5

2019

Liess, Anna K. L. ; Kucerova, Alena ; Schweimer, Kristian ; Yu, Lu ; Roumeliotis, Theodoros I. ; Diebold, Mathias ; Dybkov, Olexandr ; Sotriffer, Christoph ; Urlaub, Henning ; Choudhary, Jyoti S. ; Mansfeld, Jörg ; Lorenz, Sonja:
Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.
In: Structure. Bd. 27 (2019) Heft 8 . - S. 1195-1210.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2019.05.008

Brinson, Robert G. ; Marino, John P. ; Delaglio, Frank ; Arbogast, Luke W. ; Evans, Ryan M. ; Kearsley, Anthony ; Gingras, Geneviève ; Ghasriani, Houman ; Aubin, Yves ; Pierens, Gregory K. ; Jia, Xinying ; Mobli, Mehdi ; Grant, Hamish G. ; Keizer, David W. ; Schweimer, Kristian ; Ståhle, Jonas ; Widmalm, Göran ; Zartler, Edward R. ; Lawrence, Chad W. ; Reardon, Patrick N. ; Cort, John R. ; Xu, Ping ; Ni, Feng ; Yanaka, Saeko ; Kato, Koichi ; Parnham, Stuart R. ; Tsao, Desiree ; Blomgren, Andreas ; Rundlöf, Torgny ; Trieloff, Nils ; Schmieder, Peter ; Ross, Alfred ; Skidmore, Ken ; Chen, Kang ; Keire, David ; Freedberg, Darón I. ; Suter-Stahel, Thea ; Wider, Gerhard ; Ilc, Gregor ; Plavec, Janez ; Bradley, Scott A. ; Baldisseri, Donna M. ; Sforça, Mauricio Luis ; Zeri, Ana Carolina de Mattos ; Wei, Julie Yu ; Szabo, Christina M. ; Amezcua, Carlos A. ; Jordan, John B. ; Wikström, Mats:
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.
In: mAbs. Bd. 11 (2019) Heft 1 . - S. 94-105.
ISSN 1942-0870
DOI: https://doi.org/10.1080/19420862.2018.1544454

Jacob, Thessa ; Seutter von Loetzen, Christian ; Reuter, Andreas ; Lacher, Ulrike ; Schiller, Dirk ; Schobert, Rainer ; Mahler, Vera ; Vieths, Stefan ; Rösch, Paul ; Schweimer, Kristian ; Wöhrl, Birgitta M.:
Identification of a natural ligand of the hazel allergen Cor a 1.
In: Scientific Reports. Bd. 9 (2019) . - 8714.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-019-44999-2

Zuber, Philipp ; Schweimer, Kristian ; Rösch, Paul ; Artsimovitch, Irina ; Knauer, Stefan H.:
Reversible fold-switching controls the functional cycle of the antitermination factor RfaH.
In: Nature Communications. Bd. 10 (2019) . - 702.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-019-08567-6

Dudenhöffer, Benjamin R. ; Schneider, Hans ; Schweimer, Kristian ; Knauer, Stefan H.:
SuhB is an integral part of the ribosomal antitermination complex and interacts with NusA.
In: Nucleic Acids Research. Bd. 47 (2019) Heft 12 . - S. 6504-6518.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkz442

2018

Zuber, Philipp ; Hahn, Lukas ; Reinl, Anne ; Schweimer, Kristian ; Knauer, Stefan H. ; Gottesman, Max E. ; Rösch, Paul ; Wöhrl, Birgitta M.:
Structure and nucleic acid binding properties of KOW domains 4 and 6–7 of human transcription elongation factor DSIF.
In: Scientific Reports. Bd. 8 (2018) . - 11660.
ISSN 2045-2322
DOI: https://doi.org/10.1038/s41598-018-30042-3

Zuber, Philipp ; Artsimovitch, Irina ; NandyMazumdar, Monali ; Liu, Zhaokun ; Nedialkov, Yuri ; Schweimer, Kristian ; Rösch, Paul ; Knauer, Stefan H.:
The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand.
In: eLife. Bd. 7 (2018) . - e36349.
ISSN 2050-084X
DOI: https://doi.org/10.7554/eLife.36349

2017

Drögemüller, Johanna ; Schneider, Christin ; Schweimer, Kristian ; Strauß, Martin ; Wöhrl, Birgitta M. ; Rösch, Paul ; Knauer, Stefan H.:
Thermotoga maritima NusG : domain interaction mediates autoinhibition and thermostability.
In: Nucleic Acids Research. Bd. 45 (2017) Heft 1 . - S. 446-460.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkw1111

2016

Bauer, Joschka ; Schaal, Daniel ; Eisoldt, Lukas ; Schweimer, Kristian ; Schwarzinger, Stephan ; Scheibel, Thomas:
Acidic Residues Control the Dimerization of the N-terminal Domain of Black Widow Spiders' Major Ampullate Spidroin 1.
In: Scientific Reports. Bd. 6 (2016) . - 34442.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep34442

Schaal, Daniel ; Bauer, Joschka ; Schweimer, Kristian ; Scheibel, Thomas ; Rösch, Paul ; Schwarzinger, Stephan:
Resonance assignment of an engineered amino-terminal domain of a major ampullate spider silk with neutralized charge cluster.
In: Biomolecular NMR Assignments. Bd. 10 (2016) . - S. 199-202.
ISSN 1874-270X
DOI: https://doi.org/10.1007/s12104-016-9666-y

Strauß, Martin ; Vitiello, Christal ; Schweimer, Kristian ; Gottesman, Max E. ; Rösch, Paul ; Knauer, Stefan H.:
Transcription is regulated by NusA:NusG interaction.
In: Nucleic Acids Research. Bd. 44 (2016) Heft 12 . - S. 5971-5982.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkw423

Strauß, Martin ; Schweimer, Kristian ; Burmann, Björn M. ; Richter, Anne ; Güttler, Stephanie ; Wöhrl, Birgitta M. ; Rösch, Paul:
The two domains of Mycobacterium tuberculosis NusG protein are dynamically independent.
In: Journal of Biomolecular Structure & Dynamics. Bd. 34 (2016) Heft 2 . - S. 352-361.
ISSN 1538-0254
DOI: https://doi.org/10.1080/07391102.2015.1031700

2015

Schneider, Anna ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
AZT resistance alters enzymatic properties and creates an ATP-binding site in SFVmac reverse transcriptase.
In: Retrovirology. Bd. 12 (2015) . - 21.
ISSN 1742-4690
DOI: https://doi.org/10.1186/s12977-015-0147-7

Drögemüller, Johanna ; Strauß, Martin ; Schweimer, Kristian ; Jurk, Marcel ; Rösch, Paul ; Knauer, Stefan H.:
Determination of RNA polymerase binding surfaces of transcription factors by NMR spectroscopy.
In: Scientific Reports. Bd. 5 (2015) . - 16428.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep16428

Drögemüller, Johanna ; Strauß, Martin ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Knauer, Stefan H. ; Rösch, Paul:
Exploring RNA polymerase regulation by NMR spectroscopy.
In: Scientific Reports. Bd. 5 (2015) . - 10825.
ISSN 2045-2322
DOI: https://doi.org/10.1038/srep10825

Husslik, Felix ; Hanschmann, Kay-Martin ; Krämer, Ariane ; Seutter von Loetzen, Christian ; Schweimer, Kristian ; Bellinghausen, Iris ; Treudler, Regina ; Simon, Jan C. ; Vogel, Lothar ; Völker, Elke ; Randow, Stefanie ; Reuter, Andreas ; Rösch, Paul ; Vieths, Stefan ; Holzhauser, Thomas ; Schiller, Dirk:
Folded or Not? Tracking Bet v 1 Conformation in Recombinant Allergen Preparations.
In: PLoS One. Bd. 10 (2015) Heft 7 . - e0132956.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0132956

2014

Corona, Angela ; Schneider, Anna ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M. ; Tramontano, Enzo:
Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 ribonuclease H inhibitors.
In: Antimicrobial Agents and Chemotherapy. Bd. 58 (2014) Heft 7 . - S. 4086-4093.
ISSN 1098-6596
DOI: https://doi.org/10.1128/AAC.00056-14

Seutter von Loetzen, Christian ; Hoffmann, Thomas ; Hartl, Maximilian J. ; Schweimer, Kristian ; Schwab, Wilfried ; Rösch, Paul ; Hartl-Spiegelhauer, Olivia:
Secret of the major birch pollen allergen Bet v 1 : identification of the physiological ligand.
In: Biochemical Journal. Bd. 457 (2014) Heft 3 . - S. 379-390.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20130413

2013

Drögemüller, Johanna ; Stegmann, Christian M. ; Mandal, Angshuman ; Steiner, Thomas ; Burmann, Björn M. ; Gottesman, Max E. ; Wöhrl, Birgitta M. ; Rösch, Paul ; Wahl, Markus C. ; Schweimer, Kristian:
An Autoinhibited State in the Structure of Thermotoga maritima NusG.
In: Structure. Bd. 21 (2013) Heft 3 . - S. 365-375.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2012.12.015

2012

Camilloni, Carlo ; Schaal, Daniel ; Schweimer, Kristian ; Schwarzinger, Stephan ; de Simone, Alfonso:
Energy landscape of the prion protein helix 1 probed by metadynamics and NMR.
In: Biophysical Journal. Bd. 102 (2012) Heft 1 . - S. 158-167.
ISSN 1542-0086
DOI: https://doi.org/10.1016/j.bpj.2011.12.003

Hartl, Maximilian J. ; Burmann, Björn M. ; Prasch, Stefan J. ; Schwarzinger, Clemens ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Rösch, Paul ; Schwarzinger, Stephan:
Fast Mapping of Biomolecular Interfaces by Random Spin Labeling (RSL).
In: Journal of Biomolecular Structure & Dynamics. Bd. 29 (2012) Heft 4 . - S. 793-798.
ISSN 1538-0254

Burmann, Björn M. ; Knauer, Stefan H. ; Sevostyanova, Anastasia ; Schweimer, Kristian ; Mooney, Rachel A. ; Landick, Robert ; Artsimovitch, Irina ; Rösch, Paul:
An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor.
In: Cell. Bd. 150 (2012) Heft 2 . - S. 291-303.
ISSN 1097-4172
DOI: https://doi.org/10.1016/j.cell.2012.05.042

Härteis, Silke ; Schaal, Daniel ; Brauer, Felix ; Brüschke, Stefan ; Schweimer, Kristian ; Rauh, Robert ; Sticht, Heinrich ; Rösch, Paul ; Schwarzinger, Stephan ; Korbmacher, Christoph:
An inhibitory peptide derived from the alpha-subunit of the epithelial sodium channel (ENaC) shows a helical conformation.
In: Cellular Physiology and Biochemistry. Bd. 29 (2012) . - S. 761-774.
ISSN 1421-9778
DOI: https://doi.org/10.1159/000312590

Leo, Berit ; Hartl, Maximilian J. ; Schweimer, Kristian ; Mayr, Florian ; Wöhrl, Birgitta M.:
Insights into the structure and activity of prototype foamy virus RNase H.
In: Retrovirology. Bd. 9 (2012) Heft 1 .
ISSN 1742-4690
DOI: https://doi.org/10.1186/1742-4690-9-14

Leo, Berit ; Schweimer, Kristian ; Rösch, Paul ; Hartl, Maximilian J. ; Wöhrl, Birgitta M.:
The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding.
In: Retrovirology. Bd. 9 (2012) . - 73.
ISSN 1742-4690
DOI: https://doi.org/10.1186/1742-4690-9-73

Seutter von Loetzen, Christian ; Schweimer, Kristian ; Schwab, Wilfried ; Rösch, Paul ; Hartl-Spiegelhauer, Olivia:
Solution structure of the strawberry allergen Fra a 1.
In: Bioscience Reports. Bd. 32 (2012) Heft 6 . - S. 567-575.
ISSN 1573-4935
DOI: https://doi.org/10.1042/BSR20120058

2011

Unal, Can ; Schwedhelm, Kai F. ; Thiele, Alexandra ; Weiwad, Matthias ; Schweimer, Kristian ; Frese, Frederike ; Fischer, Gunter ; Hacker, Jörg ; Faber, Cornelius ; Steinert, Michael:
Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration.
In: Cellular Microbiology. Bd. 13 (2011) Heft 10 . - S. 1558-1572.
ISSN 1462-5822
DOI: https://doi.org/10.1111/j.1462-5822.2011.01641.x

Burmann, Björn M. ; Scheckenhofer, Ulrich ; Schweimer, Kristian ; Rösch, Paul:
Domain interactions of the transcription-translation coupling factor Escherichia coli NusG are intermolecular and transient.
In: Biochemical Journal. Bd. 435 (2011) Heft 3 . - S. 783-789.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20101679

Schweimer, Kristian ; Prasch, Stefan J. ; Sujatha, Pagadala Santhanam ; Bubunenko, Mikhail ; Gottesman, Max E. ; Rösch, Paul:
NusA Interaction with the α Subunit of E. coli RNA Polymerase Is via the UP Element Site and Releases Autoinhibition.
In: Structure. Bd. 19 (2011) Heft 7 . - S. 945-954.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2011.03.024

Juli, Christina ; Sippel, Martin ; Jäger, Jens ; Thiele, Alexandra ; Weiwad, Matthias ; Schweimer, Kristian ; Rösch, Paul ; Steinert, Michael ; Sotriffer, Christoph ; Holzgrabe, Ulrike:
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.
In: Journal of Medicinal Chemistry. Bd. 54 (2011) Heft 1 . - S. 277-283.
ISSN 1520-4804
DOI: https://doi.org/10.1021/jm101156y

Polzien, Lisa ; Baljuls, Angela ; Roth, Heide-Marie ; Kuper, Jochen ; Benz, Roland ; Schweimer, Kristian ; Hekman, Mirko ; Rapp, Ulf R.:
Pore-forming activity of BAD is regulated by specific phosphorylation and structural transitions of the C-terminal part.
In: Biochimica et Biophysica Acta : General Subjects. Bd. 1810 (2011) Heft 2 . - S. 162-169.
ISSN 1872-8006
DOI: https://doi.org/10.1016/j.bbagen.2010.11.002

2010

Hartl, Maximilian J. ; Schweimer, Kristian ; Reger, Martin ; Schwarzinger, Stephan ; Bodem, Jochen ; Rösch, Paul ; Wöhrl, Birgitta M.:
Formation of transient dimers by a retroviral protease.
In: Biochemical Journal. Bd. 427 (2010) Heft 2 . - S. 197-203.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20091451

Burmann, Björn M. ; Schweimer, Kristian ; Luo, Xiao ; Wahl, Markus C. ; Stitt, Barbara L. ; Gottesman, Max E. ; Rösch, Paul:
A NusE:NusG complex links transcription and translation.
In: Science. Bd. 328 (2010) Heft 5977 . - S. 501-504.
ISSN 1095-9203
DOI: https://doi.org/10.1126/science.1184953

2009

Mangels, Christian ; Frank, Andreas ; Ziegler, Jan ; Klingenstein, R. ; Schweimer, Kristian ; Willbold, Dieter ; Korth, Carsten ; Rösch, Paul ; Schwarzinger, Stephan:
Binding of TCA to the Prion Protein : Mechanism, Implication for Therapy, and Application as Probe for Complex Formation of Bio-macromolecules.
In: Journal of Biomolecular Structure & Dynamics. Bd. 27 (2009) Heft 2 . - S. 163-170.
ISSN 1538-0254
DOI: https://doi.org/10.1080/07391102.2009.10507306

Berkner, Hanna ; Neudecker, Philipp ; Mittag, Diana ; Ballmer-Weber, Barbara K. ; Schweimer, Kristian ; Vieths, Stefan ; Rösch, Paul:
Cross-reactivity of pollen and food allergens : soybean Gly m 4 is a member of the Bet v 1 superfamily and closely resembles yellow lupine proteins.
In: Bioscience Reports. Bd. 29 (2009) Heft 3 . - S. 183-192.
ISSN 1573-4935
DOI: https://doi.org/10.1042/BSR20080117

Knake, Claudia ; Burmann, Björn M. ; Schweimer, Kristian ; Matecko, Irena ; Rösch, Paul:
The Membrane Proximal Extracellular Domain of Human hGC-B Folds Independently.
In: Journal of Biomolecular Structure & Dynamics. Bd. 26 (2009) Heft 4 . - S. 465-72.
ISSN 1538-0254
DOI: https://doi.org/10.1080/07391102.2009.10507261

Weininger, Ulrich ; Haupt, Caroline ; Schweimer, Kristian ; Graubner, Wenke ; Kovermann, Michael ; Brüser, Thomas ; Scholz, Christian ; Schaarschmidt, Peter ; Zoldák, Gabriel ; Schmid, Franz X. ; Balbach, Jochen:
NMR solution structure of SlyD from Escherichia coli : spatial separation of prolyl isomerase and chaperone function.
In: Journal of Molecular Biology. Bd. 387 (2009) Heft 2 . - S. 295-305.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2009.01.034

Weininger, Ulrich ; Jakob, Roman P. ; Eckert, Barbara ; Schweimer, Kristian ; Schmid, Franz X. ; Balbach, Jochen:
A remote prolyl isomerization controls domain assembly via a hydrogen bonding network.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 106 (2009) Heft 30 . - 12335 -12340.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.0902102106

Kellner, Ruth ; Mangels, Christian ; Schweimer, Kristian ; Prasch, Stefan J. ; Weiglmeier, Philipp Richard ; Rösch, Paul ; Schwarzinger, Stephan:
SEMPRE: Spectral Editing Mediated by Paramagnetic Relaxation Enhancement.
In: Journal of the American Chemical Society. Bd. 131 (2009) Heft 50 . - S. 18016-18017.
ISSN 1520-5126
DOI: https://doi.org/10.1021/ja905412z

Mooney, Rachel A. ; Schweimer, Kristian ; Rösch, Paul ; Gottesman, Max E. ; Landick, Robert:
Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators.
In: Journal of Molecular Biology. Bd. 391 (2009) Heft 2 . - S. 341-358.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2009.05.078

2008

Berkner, Hanna ; Schweimer, Kristian ; Matecko, Irena ; Rösch, Paul:
Conformation, catalytic site, and enzymatic mechanism of the PR10 allergen-related enzyme norcoclaurine synthase.
In: Biochemical Journal. Bd. 413 (2008) Heft 2 . - S. 281-290.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20080306

Rao Jampani, Nageswara ; Schweimer, Kristian ; Wenzel, Sabine ; Wöhrl, Birgitta M. ; Rösch, Paul:
NELF-E RRM undergoes major structural changes in flexible protein regions on target RNA binding.
In: Biochemistry. Bd. 47 (2008) Heft 12 . - S. 3756-3761.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi702429m

Wenzel, Sabine ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
The small hSpt4 subunit of the human transcription elongation factor DSIF is a Zn-finger protein with α/β type topology.
In: Biochemical and Biophysical Research Communications. Bd. 370 (2008) Heft 3 . - S. 414-418.
ISSN 1090-2104
DOI: https://doi.org/10.1016/j.bbrc.2008.03.080

Schweimer, Kristian ; Petersen, Arnd ; Suck, Roland ; Becker, Wolf-Meinhard ; Rösch, Paul ; Matecko, Irena:
Solution structure of Phl p 3, a major allergen from timothy grass pollen.
In: Biological Chemistry. Bd. 389 (2008) Heft 7 . - S. 919-923.
ISSN 1437-4315
DOI: https://doi.org/10.1515/BC.2008.102

Ceymann, Andreas ; Horstmann, Martin ; Ehses, Philipp ; Schweimer, Kristian ; Paschke, Anne-Katrin ; Steinert, Michael ; Faber, Cornelius:
Solution structure of the Legionella pneumophila Mip-rapamycin complex.
In: BMC Structural Biology. Bd. 8 (2008) . - 17.
ISSN 1472-6807
DOI: https://doi.org/10.1186/1472-6807-8-17

Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Rösch, Paul ; Schweimer, Kristian:
The Solution Structure of the Simian Foamy Virus Protease Reveals a Monomeric Protein.
In: Journal of Molecular Biology. Bd. 381 (2008) Heft 1 . - S. 141-149.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.05.064

Matecko, Irena ; Burmann, Björn M. ; Schweimer, Kristian ; Kalbacher, Hubert ; Einsiedel, Jürgen ; Gmeiner, Peter ; Rösch, Paul:
Structural characterisation of the E.coli heat stable enterotoxin STh.
In: The Open Spectroscopy Journal. Bd. 2 (2008) . - S. 34-39.
ISSN 1874-3838
DOI: https://doi.org/10.2174/1874383800802010034

Löw, Christian ; Weininger, Ulrich ; Lee, Hwankyu ; Schweimer, Kristian ; Neundorf, Ines ; Beck-Sickinger, Annette G. ; Pastor, Richard W. ; Balbach, Jochen:
Structure and dynamics of Helix-0 of the N-BAR domain in Lipid Micelles and Bilayers.
In: Biophysical Journal. Bd. 95 (2008) Heft 9 . - S. 4315-4323.
ISSN 1542-0086
DOI: https://doi.org/10.1529/biophysj.108.134155

Schmalz, Holger ; Schmelz, Joachim ; Drechsler, Markus ; Yuan, Jiayin ; Walther, Andreas ; Schweimer, Kristian ; Mihut, Adriana M.:
Thermo-reversible formation of wormlike micelles with a microphase-separated corona from a semicrystalline triblock terpolymer.
In: Macromolecules. Bd. 41 (2008) Heft 9 . - S. 3235-3242.
ISSN 1520-5835
DOI: https://doi.org/10.1021/ma702417y

Burmann, Björn M. ; Uc-Mass, Augusto ; Schweimer, Kristian ; Gottesman, Max E. ; Rösch, Paul:
The Y39A mutation of HK022 Nun disrupts a boxB interaction but preserves termination activity.
In: Biochemistry. Bd. 47 (2008) Heft 28 . - S. 7335-7341.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi8004347

2007

Berkner, Hanna ; Engelhorn, Julia ; Liscombe, David K. ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Facchini, Peter J. ; Rösch, Paul ; Matecko, Irena:
High-yield expression and purification of isotopically labeled norcoclaurine synthase, a Bet v 1-homologous enzyme, from Thalictrum flavum for NMR studies.
In: Protein Expression and Purification. Bd. 56 (2007) Heft 2 . - S. 197-204.
ISSN 1046-5928
DOI: https://doi.org/10.1016/j.pep.2007.07.010

Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Schweimer, Kristian:
Sequence-specific ¹H, ¹³C and ¹⁵N resonance assignments and secondary structure of a truncated protease from Simian Foamy Virus.
In: Biomolecular NMR Assignments. Bd. 1 (2007) . - S. 175-177.
ISSN 1874-270X
DOI: https://doi.org/10.1007/s12104-007-9048-6

Bollig, Klaus ; Lamshöft, Marc ; Schweimer, Kristian ; Marner, Franz-Josef ; Budzikiewicz, Herbert ; Waffenschmidt, Sabine:
Structural analysis of linear hydroxyproline-bound O-glycans of Chlamydomonas reinhardtii : conservation of the inner core in Chlamydomonas and land plants.
In: Carbohydrate Research. Bd. 342 (2007) Heft 17 . - S. 2557-2566.
ISSN 1873-426X
DOI: https://doi.org/10.1016/j.carres.2007.08.008

2006

Horstmann, Martin ; Ehses, Philipp ; Schweimer, Kristian ; Steinert, Michael ; Kamphausen, Thilo ; Fischer, Gunter ; Hacker, Jörg ; Rösch, Paul ; Faber, Cornelius:
Domain Motions of the Mip Protein from Legionella pneumophila.
In: Biochemistry. Bd. 45 (2006) Heft 40 . - S. 12303-12311.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi060818i

Prasch, Stefan J. ; Schwarz, Sabine ; Eisenmann, Anke ; Wöhrl, Birgitta M. ; Schweimer, Kristian ; Rösch, Paul:
Interaction of the Intrinsically Unstructured Phage λ N Protein with Escherichia coli NusA.
In: Biochemistry. Bd. 45 (2006) Heft 14 . - S. 4542-4549.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi0523411

Rao Jampani, Nageswara ; Neumann, Liane ; Wenzel, Sabine ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
Structural studies on the RNA-recognition motif of NELF E, a cellular negative transcription elongation factor involved in the regulation of HIV transcription.
In: Biochemical Journal. Bd. 400 (2006) Heft 3 . - S. 449-456.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20060421

Lehmann, Katrin ; Schweimer, Kristian ; Reese, Gerald ; Randow, Stefanie ; Suhr, Martin ; Becker, Wolf-Meinhard ; Vieths, Stefan ; Rösch, Paul:
Structure and stability of 2s albumin-type peanut allergens : implications for the severity of peanut allergic reactions.
In: Biochemical Journal. Bd. 395 (2006) Heft 3 . - S. 463-472.
ISSN 1470-8728
DOI: https://doi.org/10.1042/BJ20051728

2005

Hofmann, Gregor ; Schweimer, Kristian ; Kiessling, Anke ; Hofinger, Edith ; Bauer, Finn ; Hoffmann, Silke ; Rösch, Paul ; Campbell, Iain D. ; Werner, Jörn M. ; Sticht, Heinrich:
Binding, domain orientation and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases.
In: Biochemistry. Bd. 44 (2005) Heft 39 . - S. 13043-13050.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi050814y

Eisenmann, Anke ; Schwarz, Sabine ; Prasch, Stefan J. ; Schweimer, Kristian ; Rösch, Paul:
The E. coli NusA carboxy-terminal domains are structurally similar and show specific RNAP- and λN interaction.
In: Protein Science. Bd. 14 (2005) Heft 8 . - S. 2018-2019.
ISSN 1469-896X
DOI: https://doi.org/10.1110/ps.051372205

Horstmann, Martin ; Kamphausen, Thilo ; Schweimer, Kristian ; Steinert, Michael ; Hacker, Jörg ; Haase, Axel ; Rösch, Paul ; Schweimer, Gunter ; Faber, Cornelius:
¹H, ¹³C, ¹⁵N backbone and sidechain resonance assignment of Mip⁽⁷⁷⁻²¹³⁾ the PPIase domain of the Legionella pneumophila Mip protein.
In: Journal of Biomolecular NMR. Bd. 31 (2005) Heft 1 . - S. 77-78.
ISSN 1573-5001
DOI: https://doi.org/10.1007/s10858-004-6041-6

Bauer, Finn ; Schweimer, Kristian ; Meiselbach, Heike ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich:
Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity.
In: Protein Science. Bd. 14 (2005) Heft 10 . - S. 2487-2498.
ISSN 1469-896X
DOI: https://doi.org/10.1110/ps.051563605

Marg, Bianca-Lucia ; Schweimer, Kristian ; Sticht, Heinrich ; Oesterhelt, Dieter:
A Two-α-Helix Extra Domain Mediates the Halophilic Character of a Plant-Type Ferredoxin from Halophilic Archaea.
In: Biochemistry. Bd. 44 (2005) Heft 1 . - S. 29-39.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi0485169

2004

Bauer, Finn ; Hofinger, Edith ; Hoffmann, Silke ; Rösch, Paul ; Schweimer, Kristian ; Sticht, Heinrich:
Characterization of Lck-binding elements in the herpesviral regulatory Tip protein.
In: Biochemistry. Bd. 43 (2004) Heft 47 . - S. 14932-14939.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi0485068

Eisenmann, Anke ; Schwarz, Sabine ; Rösch, Paul ; Schweimer, Kristian:
Sequence-Specific ¹H, ¹³C, ¹⁵N Resonance Assignments and Secondary Structure of the Carboxyterminal Domain of the E. coli Transcription Factor NusA.
In: Journal of Biomolecular NMR. Bd. 28 (2004) Heft 2 . - S. 193-194.
ISSN 1573-5001
DOI: https://doi.org/10.1023/B:JNMR.0000013819.55179.13

Lehmann, Katrin ; Schweimer, Kristian ; Neudecker, Philipp ; Rösch, Paul:
Sequence-specific ¹H,¹³C and ¹⁵N resonance assignments of Ara h 6, an allergenic 2S albumin from peanut.
In: Journal of Biomolecular NMR. Bd. 29 (2004) Heft 1 . - S. 93-94.
ISSN 1573-5001
DOI: https://doi.org/10.1023/B:JNMR.0000019459.57344.ce

Neudecker, Philipp ; Nerkamp, Jörg ; Eisenmann, Anke ; Nourse, Amanda ; Lauber, Thomas ; Schweimer, Kristian ; Lehmann, Katrin ; Schwarzinger, Stephan ; Ferreira, Fátima ; Rösch, Paul:
Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function.
In: Journal of Molecular Biology. Bd. 336 (2004) Heft 5 . - S. 1141-1157.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2003.12.070

2003

Lauber, Thomas ; Schulz, Axel ; Schweimer, Kristian ; Adermann, Knut ; Marx, Ute C.:
Homologous Proteins with Different Folds : The Three-Dimensional Structures of Domains 1 and 6 of the Multiple Kazal-Type Inhibitor LEKTI.
In: Journal of Molecular Biology. Bd. 328 (2003) Heft 1 . - S. 205-219.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(03)00245-6

Schweimer, Kristian ; Kiessling, Anke ; Bauer, Finn ; Hör, Simon ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich:
Sequence-specific ¹H, ¹³C and ¹⁵N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck.
In: Journal of Biomolecular NMR. Bd. 27 (2003) Heft 4 . - S. 405-406.
ISSN 1573-5001
DOI: https://doi.org/10.1023/A:1025861326222

2002

Schweimer, Kristian ; Hoffmann, Silke ; Bauer, Finn ; Friedrich, Ute ; Kardinal, Christian ; Feller, Stephan M. ; Biesinger, Brigitte ; Sticht, Heinrich:
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck.
In: Biochemistry. Bd. 41 (2002) Heft 16 . - S. 5120-5130.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi015986j

2001

Neudecker, Philipp ; Schweimer, Kristian ; Nerkamp, Jörg ; Scheurer, Stephan ; Vieths, Stefan ; Sticht, Heinrich ; Rösch, Paul:
Allergic cross-reactivity made visible : solution structure of the major cherry allergen Pru av 1.
In: The Journal of Biological Chemistry. Bd. 276 (2001) Heft 25 . - S. 22756-22763.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M101657200

Heger, Peter ; Lohmaier, Jens ; Schneider, Grit ; Schweimer, Kristian ; Stauber, Roland H.:
Qualitative highly divergent nuclear export signals can regulate export by the competition for transport cofactors in vivo.
In: Traffic. Bd. 2 (2001) Heft 8 . - S. 544-555.
ISSN 1600-0854
DOI: https://doi.org/10.1034/j.1600-0854.2001.20804.x

Bauer, Finn ; Schweimer, Kristian ; Klüver, Enno ; Conejo-Garcia, Jose-Ramon ; Forssmann, Wolf-Georg ; Rösch, Paul ; Adermann, Knut ; Sticht, Heinrich:
Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity.
In: Protein Science. Bd. 10 (2001) Heft 12 . - S. 2470-2479.
ISSN 1469-896X
DOI: https://doi.org/10.1110/ps.24401

2000

Schärpf, Manuela ; Sticht, Heinrich ; Schweimer, Kristian ; Boehm, Markus ; Hoffmann, Silke ; Rösch, Paul:
Antitermination in bacteriophage λ : the structure of the N36 peptide-boxB RNA complex.
In: European Journal of Biochemistry. Bd. 267 (2000) Heft 8 . - S. 2397-2408.
ISSN 1432-1033
DOI: https://doi.org/10.1046/j.1432-1327.2000.01251.x

Schweimer, Kristian:
Mehrdimensionale heteronukleare NMR-Spektroskopie zur Bestimmung der Strukturen des Birkenpollenallergens Bet v 1, des Guillardia-theta-Rubredoxins und des [2Fe-2S]-Ferredoxins aus Halobacterium salinarum.
Bayreuth , 2000 . - III, 238 S.
( Dissertation, 2000 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)

Schweimer, Kristian ; Marg, Bianca-Lucia ; Oesterhelt, Dieter ; Rösch, Paul ; Sticht, Heinrich:
Sequence-specific 1H, 13C and 15N resonance assignments and secondary structure of [2Fe-2S] ferredoxin from Halobacterium salinarum.
In: Journal of Biomolecular NMR. Bd. 16 (2000) Heft 4 . - S. 347-348.
ISSN 1573-5001
DOI: https://doi.org/10.1023/A:1008381016258

Neudecker, Philipp ; Schweimer, Kristian ; Nerkamp, Jörg ; Boehm, Markus ; Scheurer, Stephan ; Vieths, Stefan ; Sticht, Heinrich ; Rösch, Paul:
Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1.
In: Journal of Biomolecular NMR. Bd. 18 (2000) Heft 1 . - S. 71-72.
ISSN 1573-5001
DOI: https://doi.org/10.1023/A:1008357100592

Schweimer, Kristian ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich ; Wastl, Jürgen ; Maier, Uwe-G.:
Solution structure of a zinc substituted eukaryotic rubredoxin from the cryptomonad alga Guillardia theta.
In: Protein Science. Bd. 9 (2000) Heft 8 . - S. 1474-1486.
ISSN 1469-896X
DOI: https://doi.org/10.1110/ps.9.8.1474

Faber, Cornelius ; Sticht, Heinrich ; Schweimer, Kristian ; Rösch, Paul:
Structural Rearrangements of HIV-1 Tat-responsive RNA upon Binding of Neomycin B.
In: The Journal of Biological Chemistry. Bd. 275 (2000) Heft 27 . - S. 20660-20666.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M000920200

1999

Schweimer, Kristian ; Sticht, Heinrich ; Nerkamp, Jörg ; Boehm, Markus ; Breitenbach, Michael ; Vieths, Stefan ; Rösch, Paul:
NMR Spectroscopy Reveals Common Structural Features of the Birch Pollen Allergen Bet v 1 and the Cherry Allergen Pru a 1.
In: Applied Magnetic Resonance. Bd. 17 (1999) . - S. 449-464.
ISSN 1613-7507
DOI: https://doi.org/10.1007/BF03162177

Sticht, Heinrich ; Escher, Sylvia E. ; Schweimer, Kristian ; Forssmann, Wolf-Georg ; Rösch, Paul ; Adermann, Knut:
Solution structure of the human CC chemokine 2 : A monomeric representative of the CC chemokine subtype.
In: Biochemistry. Bd. 38 (1999) Heft 19 . - S. 5995-6002.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi990065i