Veröffentlichungen "Weyand, Michael"

Artikel in einer Zeitschrift

Pannek, Martin ; Alhalabi, Zayan ; Tomaselli, Daniela ; Menna, Martina ; Fiorentino, Francesco ; Robaa, Dina ; Weyand, Michael ; Puhlmann, Maximilian ; Tomassi, Stefano ; Barreca, Federica ; Tafani, Marco ; Zaganjor, Elma ; Haigis, Marcia C. ; Sippl, Wolfgang ; Rotili, Dante ; Mai, Antonello ; Steegborn, Clemens:
Specific Inhibitors of Mitochondrial Deacylase Sirtuin 4 Endowed with Cellular Activity.
In: Journal of Medicinal Chemistry. Bd. 67 (2024) Heft 3 . - S. 1843-1860.
ISSN 1520-4804
DOI: https://doi.org/10.1021/acs.jmedchem.3c01496

Adolph, Ramona S. ; Beck, Eileen ; Schweimer, Kristian ; Di Fonzo, Andrea ; Weyand, Michael ; Rösch, Paul ; Wöhrl, Birgitta M. ; Steegborn, Clemens:
Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein.
In: Life. Bd. 13 (2023) Heft 4 . - 949.
ISSN 2075-1729
DOI: https://doi.org/10.3390/life13040949

Zwergel, Clemens ; Aventaggiato, Michele ; Garbo, Sabrina ; Di Bello, Elisabetta ; Fassari, Bruno ; Noce, Beatrice ; Castiello, Carola ; Lambona, Chiara ; Barreca, Federica ; Rotili, Dante ; Fioravanti, Rossella ; Schmalz, Thomas ; Weyand, Michael ; Niedermeier, Amelie ; Tripodi, Marco ; Colotti, Gianni ; Steegborn, Clemens ; Battistelli, Cecilia ; Tafani, Marco ; Valente, Sergio ; Mai, Antonello:
Novel 1,4-Dihydropyridines as Specific Binders and Activators of SIRT3 Impair Cell Viability and Clonogenicity and Downregulate Hypoxia-Induced Targets in Cancer Cells.
In: Journal of Medicinal Chemistry. Bd. 66 (2023) Heft 14 . - S. 9622-9641.
ISSN 1520-4804
DOI: https://doi.org/10.1021/acs.jmedchem.3c00337

Dietler, Julia ; Gelfert, Renate ; Kaiser, Jennifer ; Borin, Veniamin ; Renzl, Christian ; Pilsl, Sebastian ; Ranzani, Américo Tavares ; García de Funtes, Andrés ; Gleichmann, Tobias ; Diensthuber, Ralph P. ; Weyand, Michael ; Mayer, Günter ; Schapiro, Igor ; Möglich, Andreas:
Signal transduction in light-oxygen-voltage receptors lacking the active-site glutamine.
In: Nature Communications. Bd. 13 (2022) . - 2618.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-022-30252-4

Dietler, Julia ; Schubert, Roman ; Krafft, Tobias G. A. ; Meiler, Simone ; Kainrath, Stephanie ; Richter, Florian ; Schweimer, Kristian ; Weyand, Michael ; Janovjak, Harald ; Möglich, Andreas:
A Light-Oxygen-Voltage Receptor Integrates Light and Temperature.
In: Journal of Molecular Biology. Bd. 433 (2021) Heft 15 . - 167107.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2021.167107

Unverzagt, Carlo ; Reif, Andreas ; Lam, Kevin ; Weidler, Sascha ; Lott, Marie ; Boos, Irene ; Lokau, Juliane ; Bretscher, Christian ; Mönnich, Manuel ; Perkams, Lukas ; Schmälzlein, Marina ; Graf, Christopher G. F. ; Fischer, Jan-Patrick ; Lechner, Carolin ; Hallstein, Kerstin ; Becker, Stefan ; Weyand, Michael ; Steegborn, Clemens ; Schultheiss, Gerhard ; Rose-John, Stefan ; Garbers, Christoph:
Natural Glycoforms of Human Interleukin 6 show atypical plasma clearance.
In: Angewandte Chemie International Edition. Bd. 60 (2021) Heft 24 . - S. 13380-13387.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.202101496

López-Méndez, Blanca ; Baron, Bruno ; Brautigam, Chad A. ; Jowitt, Thomas A. ; Knauer, Stefan H. ; Uebel, Stephan ; Williams, Mark A. ; Sedivy, Arthur ; Abian, Olga ; Abreu, Celeste ; Adamczyk, Malgorzata ; Bal, Wojciech ; Berger, Sylvie ; Buell, Alexander K. ; Carolis, Carlo ; Daviter, Tina ; Fish, Alexander ; Garcia-Alai, Maria ; Guenther, Christian ; Hamacek, Josef ; Hoková, Jitka ; Houser, Josef ; Johnson, Chris ; Kelly, Sharon ; Leech, Andrew ; Mas, Caroline ; Matulis, Daumantas ; McLaughlin, Stephen H. ; Montserret, Roland ; Nasreddine, Rouba ; Nehmé, Reine ; Nguyen, Quyen ; Ortega-Alarcón, David ; Perez, Kathryn ; Pirc, Katja ; Piszczek, Grzegorz ; Podobnik, Marjetka ; Rodrigo, Natalia ; Rokov-Plavec, Jasmina ; Schäfer, Susanne ; Sharpe, Tim ; Southall, June ; Staunton, David ; Tavares, Pedro ; Vanek, Ondrej ; Weyand, Michael ; Wu, Di:
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith : a multi laboratory benchmark study.
In: European Biophysics Journal with Biophysics Letters. Bd. 50 (2021) . - S. 411-427.
ISSN 1432-1017
DOI: https://doi.org/10.1007/s00249-021-01532-6

Linder, Jürgen ; Hupfeld, Enrico ; Weyand, Michael ; Steegborn, Clemens ; Moniot, Sébastien:
Crystal structure of a class III adenylyl cyclase-like ATP-binding protein from Pseudomonas aeruginosa.
In: Journal of Structural Biology. Bd. 211 (2020) Heft 2 . - 107534.
ISSN 1047-8477
DOI: https://doi.org/10.1016/j.jsb.2020.107534

Graf, Christopher G. F. ; Schulz, Christian ; Schmälzlein, Marina ; Heinlein, Christian ; Mönnich, Manuel ; Perkams, Lukas ; Püttner, Markus ; Boos, Irene ; Hessefort, Markus ; Lombana Sanchez, Jose Nelson ; Weyand, Michael ; Steegborn, Clemens ; Breiden, Bernadette ; Ross, Kerstin ; Schwarzmann, Günter ; Sandhoff, Konrad ; Unverzagt, Carlo:
Synthetic Glycoforms Reveal Carbohydrate-Dependent Bioactivity of Human Saposin D.
In: Angewandte Chemie International Edition. Bd. 56 (2017) Heft 19 . - S. 5252-5257.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.201701362

Kleinbölting, Silke ; Diaz, Ana ; Moniot, Sébastien ; van den Heuvel, Joop ; Weyand, Michael ; Levin, Lonny R. ; Buck, Jochen ; Steegborn, Clemens:
Crystal structures of human soluble adenylyl cyclase reveal mechanisms of catalysis and of its activation through bicarbonate.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 111 (2014) Heft 10 . - S. 3727-3732.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.1322778111

Kleinbölting, Silke ; van den Heuvel, Joop ; Kambach, Christian ; Weyand, Michael ; Leipelt, Martina ; Steegborn, Clemens:
Expression, purification, crystallization and preliminary X-ray diffraction analysis of a mammalian type 10 adenylyl cyclase.
In: Acta Crystallographica Section F. Bd. 70 (2014) Heft 4 . - S. 467-469.
ISSN 2053-230X
DOI: https://doi.org/10.1107/S2053230X14004014

Gertz, Melanie ; Fischer, Frank ; Nguyen, Giang Thi Tuyet ; Lakshminarasimhan, Mahadevan ; Schutkowski, Mike ; Weyand, Michael ; Steegborn, Clemens:
Ex-527 inhibits Sirtuins by exploiting their unique NAD+-dependent deacetylation mechanism.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 110 (2013) Heft 30 . - S. E2772-E2781.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.1303628110

Nguyen, Giang Thi Tuyet ; Schäfer, Susanne ; Gertz, Melanie ; Weyand, Michael ; Steegborn, Clemens:
Structures of human sirtuin 3 complexes with ADP-ribose and with carba-NAD+ and SRT1720: binding details and inhibition mechanism.
In: Acta Crystallographica Section D. Bd. 69 (2013) Heft 8 . - S. 1423-1432.
ISSN 1399-0047
DOI: https://doi.org/10.1107/S0907444913015448

Moniot, Sébastien ; Weyand, Michael ; Steegborn, Clemens:
Structures, substrates, and regulators of Mammalian sirtuins : opportunities and challenges for drug development.
In: Frontiers in Pharmacology. Bd. 3 (2012) . - 16.
ISSN 1663-9812
DOI: https://doi.org/10.3389/fphar.2012.00016

Russwurm, Michael ; Schlicker, Christine ; Weyand, Michael ; Koesling, Doris ; Steegborn, Clemens:
Crystal structure of the GAF-B domain from human phosphodiesterase 5.
In: Proteins. Bd. 79 (2011) Heft 5 . - S. 1682-1687.
ISSN 1097-0134
DOI: https://doi.org/10.1002/prot.22989