Veröffentlichungen "Hennig, Janosch"

2025

Lomoschitz, Andrea ; Meyer, Julia ; Guitart, Tanit ; Krepl, Miroslav ; Lapouge, Karine ; Hayn, Clara ; Schweimer, Kristian ; Simon, Bernd ; Šponer, Jiří ; Gebauer, Fátima ; Hennig, Janosch:
The Drosophila RNA binding protein Hrp48 binds a specific RNA sequence of the msl-2 mRNA 3' UTR to regulate translation.
In: Biophysical Chemistry. Bd. 316 (2025) . - 107346.
ISSN 1873-4200
DOI: https://doi.org/10.1016/j.bpc.2024.107346

2024

Meyer, Julia ; Payr, Marco ; Duss, Olivier ; Hennig, Janosch:
Exploring the dynamics of messenger ribonucleoprotein-mediated translation repression.
In: Biochemical Society Transactions. (2024) .
ISSN 1470-8752
DOI: https://doi.org/10.1042/bst20231240

Castello, Alfredo ; Álvarez, Lucía ; Kamel, Wael ; Iselin, Louisa ; Hennig, Janosch:
Exploring the expanding universe of host-virus interactions mediated by viral RNA.
In: Molecular Cell. Bd. 84 (2024) Heft 19 . - S. 3706-3721.
ISSN 1097-4164
DOI: https://doi.org/10.1016/j.molcel.2024.08.027

Niedner-Boblenz, Annika ; Monecke, Thomas ; Hennig, Janosch ; Klostermann, Melina ; Hofweber, Mario ; Davydova, Elena ; Gerber, André P. ; Anosova, Irina ; Mayer, Wieland ; Müller, Marisa ; Heym, Roland Gerhard ; Janowski, Robert ; Paillart, Jean-Christophe ; Dormann, Dorothee ; Zarnack, Kathi ; Sattler, Michael ; Niessing, Dierk:
Intrinsically disordered RNA-binding motifs cooperate to catalyze RNA folding and drive phase separation.
In: Nucleic Acids Research. (2024) . - gkae1107.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkae1107

Bohl, Valentin ; Hollmann, Nele Merret ; Melzer, Tobias ; Katikaridis, Panagiotis ; Meins, Lena ; Simon, Bernd ; Flemming, Dirk ; Sinning, Irmgard ; Hennig, Janosch ; Mogk, Axel:
The Listeria monocytogenes persistence factor ClpL is a potent stand-alone disaggregase.
In: eLife. Bd. 12 (2024) . - S. 1-26.
ISSN 2050-084X
DOI: https://doi.org/10.7554/eLife.92746

Álvarez, Lucía ; Haubrich, Kevin ; Iselin, Louisa ; Gillioz, Laurent ; Ruscica, Vincenzo ; Lapouge, Karine ; Augsten, Sandra ; Huppertz, Ina ; Choudhury, Nila-Roy ; Simon, Bernd ; Masiewicz, Pawel ; Lethier, Mathilde ; Cusack, Stephen ; Rittinger, Katrin ; Gabel, Frank ; Leitner, Alexander ; Michlewski, Gracjan ; Hentze, Matthias ; Allain, Frédéric H. T. ; Castello, Alfredo ; Hennig, Janosch:
The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.
In: Nature Communications. Bd. 15 (2024) Heft 1 . - 8485.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-024-52918-x

Lang, Nina ; Jagtap, Pravin Kumar Ankush ; Hennig, Janosch:
Regulation and mechanisms of action of RNA helicases.
In: RNA Biology. Bd. 21 (2024) Heft 1 . - S. 24-38.
ISSN 1555-8584
DOI: https://doi.org/10.1080/15476286.2024.2415801

Griffith-Jones, Simonne ; Álvarez, Lucía ; Mukhopadhyay, Urbi ; Gharbi, Sarah ; Rettel, Mandy ; Adams, Michael ; Hennig, Janosch ; Bhogaraju, Sagar:
Response to Forker et al.
In: The EMBO Journal. Bd. 43 (2024) Heft 14 . - S. 2840-2842.
ISSN 1460-2075
DOI: https://doi.org/10.1038/s44318-024-00141-1

Griffith-Jones, Simonne ; Álvarez, Lucía ; Mukhopadhyay, Urbi ; Gharbi, Sarah ; Rettel, Mandy ; Adams, Michael ; Hennig, Janosch ; Bhogaraju, Sagar:
Structural basis for RAD18 regulation by MAGEA4 and its implications for RING ubiquitin ligase binding by MAGE family proteins.
In: The EMBO Journal. Bd. 43 (2024) Heft 7 . - S. 1273-1300.
ISSN 1460-2075
DOI: https://doi.org/10.1038/s44318-024-00058-9

Heber, Simone ; McClintock, Mark A. ; Simon, Bernd ; Mehtab, Eve ; Lapouge, Karine ; Hennig, Janosch ; Bullock, Simon L. ; Ephrussi, Anne:
Tropomyosin 1-I/C coordinates kinesin-1 and dynein motors during oskar mRNA transport.
In: Nature Structural & Molecular Biology. Bd. 31 (2024) . - S. 476-488.
ISSN 1545-9985
DOI: https://doi.org/10.1038/s41594-024-01212-x

2023

Hollmann, Nele Merret ; Jagtap, Pravin Kumar Ankush ; Linse, Johanna-Barbara ; Ullmann, Philip ; Payr, Marco ; Murciano, Brice ; Simon, Bernd ; Hub, Jochen S. ; Hennig, Janosch:
Upstream of N-Ras C-terminal cold shock domains mediate poly(A) specificity in a novel RNA recognition mode and bind poly(A) binding protein.
In: Nucleic Acids Research. Bd. 51 (2023) Heft 4 . - S. 1895-1913.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkac1277

Katikaridis, Panagiotis ; Simon, Bernd ; Jenne, Timo ; Moon, Seongjoon ; Lee, Changhan ; Hennig, Janosch ; Mogk, Axel:
Structural basis of aggregate binding by the AAA+ disaggregase ClpG.
In: The Journal of Biological Chemistry. Bd. 299 (2023) Heft 11 . - 105336.
ISSN 1083-351X
DOI: https://doi.org/10.1016/j.jbc.2023.105336

Jagtap, Pravin Kumar Ankush ; Müller, Marisa ; Kiss, Anna E. ; Thomae, Andreas W. ; Lapouge, Karine ; Beck, Martin ; Becker, Peter B. ; Hennig, Janosch:
Structural basis of RNA-induced autoregulation of the DExH-type RNA helicase maleless.
In: Molecular Cell. Bd. 83 (2023) Heft 23 . - S. 4318-4333.e10.
ISSN 1097-4164
DOI: https://doi.org/10.1016/j.molcel.2023.10.026

2022

Huck, Volker ; Chen, Po-Chia ; Xu, Emma-Ruoqi ; Tischer, Alexander ; Klemm, Ulrike ; Aponte-Santamaría, Camilo ; Mess, Christian ; Obser, Tobias ; Kutzki, Fabian ; König, Gesa ; Denis, Cécile V. ; Gräter, Frauke ; Wilmanns, Matthias ; Auton, Matthew ; Schneider, Stefan W. ; Schneppenheim, Reinhard ; Hennig, Janosch ; Brehm, Maria A.:
Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics.
In: Thrombosis and Haemostasis. Bd. 122 (2022) Heft 2 . - S. 226-239.
ISSN 0340-6245
DOI: https://doi.org/10.1055/a-1344-4405

Zhang, Leran ; Lovell, Scott ; De Vita, Elena ; Jagtap, Pravin Kumar Ankush ; Lucy, Daniel ; Goya Grocin, Andrea ; Kjær, Svend ; Borg, Annabel ; Hennig, Janosch ; Miller, Aubry K. ; Tate, Edward W.:
A KLK6 Activity-Based Probe Reveals a Role for KLK6 Activity in Pancreatic Cancer Cell Invasion.
In: Journal of the American Chemical Society. Bd. 144 (2022) Heft 49 . - S. 22493-22504.
ISSN 1520-5126
DOI: https://doi.org/10.1021/jacs.2c07378

Huppertz, Ina ; Perez-Perri, Joel I. ; Mantas, Panagiotis ; Sekaran, Thileepan ; Schwarzl, Thomas ; Russo, Francesco ; Ferring-Appel, Dunja ; Koskova, Zuzana ; Dimitrova-Paternoga, Lyudmila ; Kafkia, Eleni ; Hennig, Janosch ; Neveu, Pierre A. ; Patil, Kiran ; Hentze, Matthias W.:
Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation.
In: Molecular Cell. Bd. 82 (2022) Heft 14 . - S. 2666-2680.
ISSN 1097-4164
DOI: https://doi.org/10.1016/j.molcel.2022.05.019

Baumann, Andreas ; Isak, Daniel ; Lohbeck, Jasmin ; Jagtap, Pravin Kumar Ankush ; Hennig, Janosch ; Miller, Aubry:
Scalable synthesis and structural characterization of reversible KLK6 inhibitors.
In: RSC Advances. Bd. 12 (2022) Heft 41 . - S. 26989-26993.
ISSN 2046-2069
DOI: https://doi.org/10.1039/D2RA04670A

Chen, Po-chia ; Kutzki, Fabian ; Mojzisch, Angelika ; Simon, Bernd ; Xu, Emma-Ruoqi ; Aponte-Santamaria, Camilo ; Horny, Kai ; Jeffries, Cy ; Schneppenheim, Reinhard ; Wilmanns, Matthias ; Brehm, Maria A. ; Gräter, Frauke ; Hennig, Janosch:
Structure and dynamics of the von Willebrand Factor C6 domain.
In: Journal of Structural Biology. Bd. 214 (2022) Heft 4 . - 107923.
ISSN 1047-8477
DOI: https://doi.org/10.1016/j.jsb.2022.107923

Büscher, Magdalena ; Horos, Rastislav ; Huppertz, Ina ; Haubrich, Kevin ; Dobrev, Nikolay ; Baudin, Florence ; Hennig, Janosch ; Hentze, Matthias W.:
Vault RNA1–1 riboregulates the autophagic function of p62 by binding to lysine 7 and arginine 21, both of which are critical for p62 oligomerization.
In: RNA : a Publication of the RNA Society. Bd. 28 (2022) Heft 5 . - S. 742-755.
ISSN 1469-9001
DOI: https://doi.org/10.1261/rna.079129.122

2021

Wentink, Anne S. ; Nillegoda, Nadinath B. ; Feufel, Jennifer ; Ubartaitė, Gabrielė ; Schneider, Carolyn P. ; De Los Rios, Paolo ; Hennig, Janosch ; Barducci, Alessandro ; Bukau, Bernd:
Author Correction: Molecular dissection of amyloid disaggregation by human HSP70.
In: Nature. Bd. 589 (2021) . - E2.
ISSN 1476-4687
DOI: https://doi.org/10.1038/s41586-020-03090-x

Klünemann, Martina ; Andrejev, Sergej ; Blasche, Sonja ; Mateus, Andre ; Phapale, Prasad ; Devendran, Saravanan ; Vappiani, Johanna ; Simon, Bernd ; Scott, Timothy A. ; Kafkia, Eleni ; Konstantinidis, Dimitrios ; Zirngibl, Katharina ; Mastrorilli, Eleonora ; Banzhaf, Manuel ; Mackmull, Marie-Therese ; Hövelmann, Felix ; Nesme, Leo ; Brochado, Ana Rita ; Maier, Lisa ; Bock, Thomas ; Periwal, Vinita ; Kumar, Manjeet ; Kim, Yongkyu ; Tramontano, Melanie ; Schultz, Carsten ; Beck, Martin ; Hennig, Janosch ; Zimmermann, Michael ; Sévin, Daniel C. ; Cabreiro, Filipe ; Savitski, Mikhail M. ; Bork, Peer ; Typas, Athanasios ; Patil, Kiran R.:
Bioaccumulation of therapeutic drugs by human gut bacteria.
In: Nature. Bd. 597 (2021) . - S. 533-538.
ISSN 1476-4687
DOI: https://doi.org/10.1038/s41586-021-03891-8

Villa, Raffaella ; Jagtap, Pravin Kumar Ankush ; Thomae, Andreas W. ; Campos Sparr, Aline ; Forné, Ignasi ; Hennig, Janosch ; Straub, Tobias ; Becker, Peter B.:
Divergent evolution toward sex chromosome-specific gene regulation in Drosophila.
In: Genes & Development. Bd. 35 (2021) Heft 13-14 . - S. 1055-1070.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.348411.121

Dimitrova-Paternoga, Lyudmila ; Jagtap, Pravin Kumar Ankush ; Cyrklaff, Anna ; Vaishali ; Lapouge, Karine ; Sehr, Peter ; Perez, Kathryn ; Heber, Simone ; Löw, Christian ; Hennig, Janosch ; Ephrussi, Anne:
Molecular basis of mRNA transport by a kinesin-1-atypical tropomyosin complex.
In: Genes & Development. Bd. 35 (2021) Heft 13-14 . - S. 976-991.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.348443.121

Perez-Borrajero, Cecilia ; Podvalnaya, Nadezda ; Holleis, Kay ; Lichtenberger, Raffael ; Karaulanov, Emil ; Simon, Bernd ; Basquin, Jérôme ; Hennig, Janosch ; Ketting, René F. ; Falk, Sebastian:
Structural basis of PETISCO complex assembly during piRNA biogenesis in C. elegans.
In: Genes & Development. Bd. 35 (2021) Heft 17-18 . - S. 1304-1323.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.348648.121

Macošek, Jakub ; Simon, Bernd ; Linse, Johanna-Barbara ; Jagtap, Pravin Kumar Ankush ; Winter, Sophie L. ; Foot, Jaelle ; Lapouge, Karine ; Perez, Kathryn ; Rettel, Mandy ; Ivanović, Miloš T. ; Masiewicz, Pawel ; Murciano, Brice ; Savitski, Mikhail M. ; Loedige, Inga ; Hub, Jochen S. ; Gabel, Frank ; Hennig, Janosch:
Structure and dynamics of the quaternary hunchback mRNA translation repression complex.
In: Nucleic Acids Research. Bd. 49 (2021) Heft 15 . - S. 8866-8885.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkab635

Graf von Armansperg, Benedikt ; Koller, Franziska ; Gericke, Nicola ; Hellwig, Michael ; Jagtap, Pravin Kumar Ankush ; Heermann, Ralf ; Hennig, Janosch ; Henle, Thomas ; Lassak, Jürgen:
Transcriptional regulation of the Nε‐fructoselysine metabolism in Escherichia coli by global and substrate‐specific cues.
In: Molecular Microbiology. Bd. 115 (2021) Heft 2 . - S. 175-190.
ISSN 1365-2958
DOI: https://doi.org/10.1111/mmi.14608

Vaishali ; Dimitrova-Paternoga, Lyudmila ; Haubrich, Kevin ; Sun, Mai ; Ephrussi, Anne ; Hennig, Janosch:
Validation and classification of RNA binding proteins identified by mRNA interactome capture.
In: RNA : a Publication of the RNA Society. Bd. 27 (2021) . - S. 1173-1185.
ISSN 1469-9001
DOI: https://doi.org/10.1261/rna.078700.121

2020

Lassak, J. ; Schlundt, A. ; Feige, M. J. ; Hennig, Janosch:
Die GBM Young Investigators und Biological Chemistry (DeGruyter) : eine Zusammenarbeit zur Förderung des wissenschaftlichen Nachwuchses in Deutschland.
In: BIOspektrum. Bd. 26 (2020) Heft 1 . - S. 77.
ISSN 1868-6249

Dimitrova-Paternoga, Lyudmila ; Jagtap, Pravin Kumar Ankush ; Chen, Po-Chia ; Hennig, Janosch:
Integrative Structural Biology of Protein-RNA Complexes.
In: Structure. Bd. 28 (2020) Heft 1 . - S. 6-28.
ISSN 0969-2126
DOI: https://doi.org/10.1016/j.str.2019.11.017

Yang, Jie ; Talibov, Vladimir O. ; Peintner, Stefan ; Rhee, Claire ; Poongavanam, Vasanthanathan ; Geitmann, Matthis ; Sebastiano, Matteo Rossi ; Simon, Bernd ; Hennig, Janosch ; Dobritzsch, Doreen ; Danielson, U. Helena ; Kihlberg, Jan:
Macrocyclic Peptides Uncover a Novel Binding Mode for Reversible Inhibitors of LSD1.
In: ACS Omega. Bd. 5 (2020) Heft 8 . - S. 3979-3995.
ISSN 2470-1343
DOI: https://doi.org/10.1021/acsomega.9b03493

Ibarra, Ignacio L. ; Hollmann, Nele Merret ; Klaus, Bernd ; Augsten, Sandra ; Velten, Britta ; Hennig, Janosch ; Zaugg, Judith B.:
Mechanistic insights into transcription factor cooperativity and its impact on protein-phenotype interactions.
In: Nature Communications. Bd. 11 (2020) . - 124.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-019-13888-7

Wentink, Anne S. ; Nillegoda, Nadinath B. ; Feufel, Jennifer ; Ubartaitė, Gabrielė ; Schneider, Carolyn P. ; De Los Rios, Paolo ; Hennig, Janosch ; Barducci, Alessandro ; Bukau, Bernd:
Molecular dissection of amyloid disaggregation by human HSP70.
In: Nature. Bd. 587 (2020) Heft 7834 . - S. 483-488.
ISSN 1476-4687
DOI: https://doi.org/10.1038/s41586-020-2904-6

Hollmann, Nele Merret ; Jagtap, Pravin Kumar Ankush ; Masiewicz, Pawel ; Guitart, Tanit ; Simon, Bernd ; Provaznik, Jan ; Stein, Frank ; Haberkant, Per ; Sweetapple, Lara Jayne ; Villacorta, Laura ; Mooijman, Dylan ; Benes, Vladimir ; Savitski, Mikhail M. ; Gebauer, Fátima ; Hennig, Janosch:
Pseudo-RNA-Binding Domains Mediate RNA Structure Specificity in Upstream of N-Ras.
In: Cell Reports. Bd. 32 (2020) Heft 3 . - 107930.
ISSN 2211-1247
DOI: https://doi.org/10.1016/j.celrep.2020.107930

Chen, Po-Chia ; Masiewicz, Pawel ; Perez, Kathryn ; Hennig, Janosch:
Structure-based screening of binding affinities via small-angle X-ray scattering.
In: IUCrJ. Bd. 7 (2020) Heft 4 . - S. 644-655.
ISSN 2052-2525
DOI: https://doi.org/10.1107/S2052252520004169

2019

Chen, Po-Chia ; Shevchuk, Roman ; Strnad, Felix M. ; Lorenz, Charlotte ; Karge, Lukas ; Gilles, Ralph ; Stadler, Andreas M. ; Hennig, Janosch ; Hub, Jochen S.:
Combined Small-Angle X-ray and Neutron Scattering Restraints in Molecular Dynamics Simulations.
In: Journal of Chemical Theory and Computation. Bd. 15 (2019) Heft 8 . - S. 4687-4698.
ISSN 1549-9626
DOI: https://doi.org/10.1021/acs.jctc.9b00292

Williams, Felix Preston ; Haubrich, Kevin ; Perez-Borrajero, Cecilia ; Hennig, Janosch:
Emerging RNA-binding roles in the TRIM family of ubiquitin ligases.
In: Biological Chemistry. Bd. 400 (2019) Heft 11 . - S. 1443-1464.
ISSN 1437-4315
DOI: https://doi.org/10.1515/hsz-2019-0158

Feige, M. J. ; Hennig, Janosch ; Kühl, I. ; Lassak, J. ; Rabe, K. ; Reiner, A. ; Stauber, T. ; Weigand, Julia:
Die GBM Young Investigators stellen sich vor.
In: BIOspektrum. Bd. 25 (2019) Heft 2 . - S. 207.
ISSN 1868-6249

Hennig, Janosch ; Feige, Matthias J.:
Highlight : Young research groups in Germany.
In: Biological Chemistry. Bd. 400 (2019) Heft 7 . - S. 811-812.
ISSN 1437-4315
DOI: https://doi.org/10.1515/hsz-2019-0246

Hennig, Janosch ; Feige, Matthias J.:
Highlight : Young research groups in Germany – continued.
In: Biological Chemistry. Bd. 400 (2019) Heft 11 . - S. 1395.
ISSN 1437-4315
DOI: https://doi.org/10.1515/hsz-2019-0361

Hassler, Markus ; Shaltiel, Indra A. ; Kschonsak, Marc ; Simon, Bernd ; Merkel, Fabian ; Thärichen, Lena ; Bailey, Henry J. ; Macošek, Jakub ; Bravo, Sol ; Metz, Jutta ; Hennig, Janosch ; Haering, Christian H.:
Structural Basis of an Asymmetric Condensin ATPase Cycle.
In: Molecular Cell. Bd. 74 (2019) Heft 6 . - S. 1175-1188.e9.
ISSN 1097-4164
DOI: https://doi.org/10.1016/j.molcel.2019.03.037

Xu, Emma-Ruoqi ; von Bülow, Sören ; Chen, Po-Chia ; Lenting, Peter J. ; Kolšek, Katra ; Aponte-Santamaría, Camilo ; Simon, Bernd ; Foot, Jaelle ; Obser, Tobias ; Schneppenheim, Reinhard ; Gräter, Frauke ; Denis, Cécile V. ; Wilmanns, Matthias ; Hennig, Janosch:
Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor.
In: Blood. Bd. 133 (2019) Heft 4 . - S. 366-376.
ISSN 1528-0020
DOI: https://doi.org/10.1182/blood-2018-04-843615

Jagtap, Pravin Kumar Ankush ; Müller, Marisa ; Masiewicz, Pawel ; von Bülow, Sören ; Hollmann, Nele Merret ; Chen, Po-Chia ; Simon, Bernd ; Thomae, Andreas W. ; Becker, Peter B. ; Hennig, Janosch:
Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.
In: Nucleic Acids Research. Bd. 47 (2019) Heft 8 . - S. 4319-4333.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkz125

Volkwein, Wolfram ; Krafczyk, Ralph ; Jagtap, Pravin Kumar Ankush ; Parr, Marina ; Mankina, Elena ; Macošek, Jakub ; Guo, Zhenghuan ; Fürst, Maximilian Josef Ludwig Johannes ; Pfab, Miriam ; Frishman, Dmitrij ; Hennig, Janosch ; Jung, Kirsten ; Lassak, Jürgen:
Switching the Post-translational Modification of Translation Elongation Factor EF-P.
In: Frontiers in Microbiology. Bd. 10 (2019) . - 1148.
ISSN 1664-302X
DOI: https://doi.org/10.3389/fmicb.2019.01148

2018

Chen, Po-Chia ; Hologne, Maggy ; Walker, Olivier ; Hennig, Janosch:
Ab Initio Prediction of NMR Spin Relaxation Parameters from Molecular Dynamics Simulations.
In: Journal of Chemical Theory and Computation. Bd. 14 (2018) Heft 2 . - S. 1009-1019.
ISSN 1549-9626
DOI: https://doi.org/10.1021/acs.jctc.7b00750

Chen, Po-Chia ; Masiewicz, Pawel ; Rybin, Vladimir ; Svergun, Dmitri ; Hennig, Janosch:
A General Small-Angle X-ray Scattering-Based Screening Protocol Validated for Protein–RNA Interactions.
In: ACS Combinatorial Science. Bd. 20 (2018) Heft 4 . - S. 197-202.
ISSN 2156-8944
DOI: https://doi.org/10.1021/acscombsci.8b00007

Koliopoulos, Marios G. ; Lethier, Mathilde ; van der Veen, Annemarthe G. ; Haubrich, Kevin ; Hennig, Janosch ; Kowalinski, Eva ; Stevens, Rebecca V. ; Martin, Stephen R. ; Reis e Sousa, Caetano ; Cusack, Stephen ; Rittinger, Katrin:
Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition.
In: Nature Communications. Bd. 9 (2018) . - 1820.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-018-04214-8

Chen, Po-Chia ; Hennig, Janosch:
The role of small-angle scattering in structure-based screening applications.
In: Biophysical Reviews. Bd. 10 (2018) Heft 5 . - S. 1295-1310.
ISSN 1867-2469
DOI: https://doi.org/10.1007/s12551-018-0464-x

2017

Sonntag, M. ; Sattler, M. ; Gabel, Frank ; Hennig, Janosch:
Multi-domain proteins : combining neutrons and NMR makes the difference.
In: Annual Report / Institute Laue-Langevin. (2017) . - S. 12-13.
ISSN 0181-0731

Sonntag, Miriam ; Jagtap, Pravin Kumar Ankush ; Simon, Bernd ; Appavou, Marie-Sousai ; Geerlof, Arie ; Stehle, Ralf ; Gabel, Frank ; Hennig, Janosch ; Sattler, Michael:
Segmental, Domain-Selective Perdeuteration and Small-Angle Neutron Scattering for Structural Analysis of Multi-Domain Proteins.
In: Angewandte Chemie International Edition. Bd. 56 (2017) Heft 32 . - S. 9322-9325.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.201702904

Krafczyk, Ralph ; Macošek, Jakub ; Jagtap, Pravin Kumar Ankush ; Gast, Daniel ; Wunder, Swetlana ; Mitra, Prithiba ; Jha, Amit Kumar ; Rohr, Jürgen ; Hoffmann-Röder, Anja ; Jung, Kirsten ; Hennig, Janosch ; Lassak, Jürgen:
Structural Basis for EarP-Mediated Arginine Glycosylation of Translation Elongation Factor EF-P.
In: mBio. Bd. 8 (2017) Heft 5 . - e01412-17.
ISSN 2150-7511
DOI: https://doi.org/10.1128/mBio.01412-17

2016

Ernst, Robert ; Feige, Matthias J. ; Hennig, Janosch ; Hohnholt, Michaela C. ; Rabe, Kersten S. ; Reiner, Andreas:
Funding opportunities in Germany.
In: BIOspektrum. Bd. 22 (2016) Heft 5 . - S. 513.
ISSN 1868-6249

Carlon, Azzurra ; Ravera, Enrico ; Hennig, Janosch ; Parigi, Giacomo ; Sattler, Michael ; Luchinat, Claudio:
Improved Accuracy from Joint X-ray and NMR Refinement of a Protein–RNA Complex Structure.
In: Journal of the American Chemical Society. Bd. 138 (2016) Heft 5 . - S. 1601-1610.
ISSN 1520-5126
DOI: https://doi.org/10.1021/jacs.5b11598

Ernst, Robert ; Feige, Matthias ; Hennig, Janosch ; Hohnholt, Michaela C. ; Kühl, Inge ; Morgan, Bruce ; Rabe, Kersten ; Reiner, Andreas:
Neue Perspektiven für den wissenschaftlichen Nachwuchs in Deutschland.
In: BIOspektrum. Bd. 22 (2016) Heft 1 . - S. 3.
ISSN 1868-6249
DOI: https://doi.org/10.1007/s12268-016-0647-6

Li, Xiang ; Krafczyk, Ralph ; Macošek, Jakub ; Li, Yu-Lei ; Zou, Yan ; Simon, Bernd ; Pan, Xing ; Wu, Qiu-Ye ; Yan, Fang ; Li, Shan ; Hennig, Janosch ; Jung, Kirsten ; Lassak, Jürgen ; Hu, Hong-Gang:
Resolving the α-glycosidic linkage of arginine-rhamnosylated translation elongation factor P triggers generation of the first Argᴿʰᵃ specific antibody.
In: Chemical Science. Bd. 7 (2016) Heft 12 . - S. 6995-7001.
ISSN 2041-6539
DOI: https://doi.org/10.1039/c6sc02889f

2015

Loedige, Inga ; Jakob, Leonhard ; Treiber, Thomas ; Ray, Debashish ; Stotz, Mathias ; Treiber, Nora ; Hennig, Janosch ; Cook, Kate B. ; Morris, Quaid ; Hughes, Timothy R. ; Engelmann, Julia C. ; Krahn, Michael P. ; Meister, Gunter:
The Crystal Structure of the NHL Domain in Complex with RNA Reveals the Molecular Basis of Drosophila Brain-Tumor-Mediated Gene Regulation.
In: Cell Reports. Bd. 13 (2015) Heft 6 . - S. 1206-1220.
ISSN 2211-1247
DOI: https://doi.org/10.1016/j.celrep.2015.09.068

Hennig, Janosch ; Sattler, Michael:
Deciphering the protein-RNA recognition code : Combining large-scale quantitative methods with structural biology.
In: BioEssays. Bd. 37 (2015) Heft 8 . - S. 899-908.
ISSN 1521-1878
DOI: https://doi.org/10.1002/bies.201500033

Friberg, Anders ; Thumann, Sybille ; Hennig, Janosch ; Zou, Peijian ; Nössner, Elfriede ; Ling, Paul D. ; Sattler, Michael ; Kempkes, Bettina:
The EBNA-2 N-Terminal Transactivation Domain Folds into a Dimeric Structure Required for Target Gene Activation.
In: PLoS Pathogens. Bd. 11 (2015) Heft 5 . - e1004910.
ISSN 1553-7374
DOI: https://doi.org/10.1371/journal.ppat.1004910

Freiburger, Lee ; Sonntag, Miriam ; Hennig, Janosch ; Li, Jian ; Zou, Peijian ; Sattler, Michael:
Efficient segmental isotope labeling of multi-domain proteins using Sortase A.
In: Journal of Biomolecular NMR. Bd. 63 (2015) Heft 1 . - S. 1-8.
ISSN 1573-5001
DOI: https://doi.org/10.1007/s10858-015-9981-0

Ernst, Robert ; Feige, Matthias J. ; Hennig, Janosch ; Hohnholt, Michaela C. ; Hopp, Christine ; Morgan, Bruce ; Rabe, Kersten ; Reiner, Andreas:
GBM Young Investigators.
In: BIOspektrum. Bd. 21 (2015) Heft 5 . - S. 535.
ISSN 1868-6249

Hennig, Janosch ; Andrésen, Cecilia ; Museth, A. Katrine ; Lundström, Patrik ; Tibell, Lena A. E. ; Jonsson, Bengt-Harald:
Local Destabilization of the Metal-Binding Region in Human Copper–Zinc Superoxide Dismutase by Remote Mutations Is a Possible Determinant for Progression of ALS.
In: Biochemistry. Bd. 54 (2015) Heft 2 . - S. 323-333.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi500606j

Hennig, Janosch ; Warner, Lisa R. ; Simon, Bernd ; Geerlof, Arie ; Mackereth, Cameron D. ; Sattler, Michael:
Structural Analysis of Protein–RNA Complexes in Solution Using NMR Paramagnetic Relaxation Enhancements.
In: Woodson, Sarah A. ; Allain, Frédéric H. T. (Hrsg.): Structures of Large RNA Molecules and Their Complexes. - Amsterdam ; Heidelberg : Academic Press , 2015 . - S. 333-362 . - (Methods in Enzymology ; 558 )
ISBN 978-0-12-801934-4
DOI: https://doi.org/10.1016/bs.mie.2015.02.006

Horn, Annemarie ; Hennig, Janosch ; Ahmed, Yasar L. ; Stier, Gunter ; Wild, Klemens ; Sattler, Michael ; Sinning, Irmgard:
Structural basis for cpSRP43 chromodomain selectivity and dynamics in Alb3 insertase interaction.
In: Nature Communications. Bd. 6 (2015) . - 8875.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms9875

2014

Hennig, Janosch ; Gebauer, Fátima ; Sattler, Michael:
Breaking the protein-RNA recognition code.
In: Cell Cycle. Bd. 13 (2014) Heft 23 . - S. 3619-3620.
ISSN 1551-4005
DOI: https://doi.org/10.4161/15384101.2014.986625

Hennig, Janosch ; Sattler, Michael:
The dynamic duo : Combining NMR and small angle scattering in structural biology.
In: Protein Science. Bd. 23 (2014) Heft 6 . - S. 669-682.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.2467

Gabel, Frank ; Hennig, Janosch ; Sattler, M.:
Neutrons help to reveal the structural basis of a gene-regulation mechanism in Drosophila flies.
In: Annual Report / Institute Laue-Langevin. (2014) . - S. 64-65.
ISSN 0181-0731

Loedige, Inga ; Stotz, Mathias ; Qamar, Saadia ; Kramer, Katharina ; Hennig, Janosch ; Schubert, Thomas ; Löffler, Patrick ; Längst, Gernot ; Merkl, Rainer ; Urlaub, Henning ; Meister, Gunter:
The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.
In: Genes & Development. Bd. 28 (2014) Heft 7 . - S. 749-764.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.236513.113

Feige, Matthias J. ; Grawert, Melissa A. ; Marcinowski, Moritz ; Hennig, Janosch ; Behnke, Julia ; Ausländer, David ; Herold, Eva M. ; Peschek, Jirka ; Castro, Caitlin D. ; Flajnik, Martin ; Hendershot, Linda M. ; Sattler, Michael ; Groll, Michael ; Buchner, Johannes:
The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 111 (2014) Heft 22 . - S. 8155-8160.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.1321502111

Hennig, Janosch ; Militti, Cristina ; Popowicz, Grzegorz M. ; Wang, Iren ; Sonntag, Miriam ; Geerlof, Arie ; Gabel, Frank ; Gebauer, Fátima ; Sattler, Michael:
Structural basis for the assembly of the Sxl–Unr translation regulatory complex.
In: Nature. Bd. 515 (2014) Heft 7526 . - S. 287-290.
ISSN 1476-4687
DOI: https://doi.org/10.1038/nature13693

Wang, Iren ; Hennig, Janosch ; Jagtap, Pravin Kumar Ankush ; Sonntag, Miriam ; Valcárcel, Juan ; Sattler, Michael:
Structure, dynamics and RNA binding of the multi-domain splicing factor TIA-1.
In: Nucleic Acids Research. Bd. 42 (2014) Heft 9 . - S. 5949-5966.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gku193

2013

Hennig, Janosch ; Wang, Iren ; Sonntag, Miriam ; Gabel, Frank ; Sattler, Michael:
Combining NMR and small angle X-ray and neutron scattering in the structural analysis of a ternary protein-RNA complex.
In: Journal of Biomolecular NMR. Bd. 56 (2013) Heft 1 . - S. 17-30.
ISSN 1573-5001
DOI: https://doi.org/10.1007/s10858-013-9719-9

Weininger, Ulrich ; Blissing, Annica T. ; Hennig, Janosch ; Ahlner, Alexandra ; Liu, Zhihong ; Vogel, Hans J. ; Akke, Mikael ; Lundström, Patrik:
Protein conformational exchange measured by ¹H R₁ρ relaxation dispersion of methyl groups.
In: Journal of Biomolecular NMR. Bd. 57 (2013) Heft 1 . - S. 47-55.
ISSN 1573-5001
DOI: https://doi.org/10.1007/s10858-013-9764-4

Pfaff, Janina ; Hennig, Janosch ; Herzog, Franz ; Aebersold, Ruedi ; Sattler, Michael ; Niessing, Dierk ; Meister, Gunter:
Structural features of Argonaute-GW182 protein interactions.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 110 (2013) Heft 40 . - S. E3770-E3779.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.1308510110

2012

Hennig, Janosch ; de Vries, Sjoerd J. ; Hennig, Klaus D. M. ; Randles, Leah ; Walters, Kylie J. ; Sunnerhagen, Maria ; Bonvin, Alexandre M. J. J.:
MTMDAT-HADDOCK : High-throughput, protein complex structure modeling based on limited proteolysis and mass spectrometry.
In: BMC Structural Biology. Bd. 12 (2012) . - 29.
ISSN 1472-6807
DOI: https://doi.org/10.1186/1472-6807-12-29

Sattler, Michael ; Hennig, Janosch:
The NMI3 Deuteration Lab : Combining neutrons and NMR spectroscopy at TUM.
In: FRM II news. Bd. 9 (2012) . - S. 18-19.

Wennerstrand, Patricia ; Dametto, Paolo ; Hennig, Janosch ; Klingstedt, Therése ; Skoglund, Karin ; Lindqvist Appell, Malin ; Mårtensson, Lars-Göran:
Structural Characteristics Determine the Cause of the Low Enzyme Activity of Two Thiopurine S-Methyltransferase Allelic Variants : A Biophysical Characterization of TPMT*2 and TPMT*5.
In: Biochemistry. Bd. 51 (2012) Heft 30 . - S. 5912-5920.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi300377d

2011

Espinosa, Alexander ; Hennig, Janosch ; Ambrosi, Aurélie ; Anandapadmanaban, Madhanagopal ; Abelius, Martina Sandberg ; Sheng, Yi ; Nyberg, Filippa ; Arrowsmith, Cheryl H. ; Sunnerhagen, Maria ; Wahren-Herlenius, Marie:
Anti-Ro52 Autoantibodies from Patients with Sjögren's Syndrome Inhibit the Ro52 E3 Ligase Activity by Blocking the E3/E2 Interface.
In: The Journal of Biological Chemistry. Bd. 286 (2011) Heft 42 . - S. 36478-36491.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M111.241786

2008

Hennig, Janosch ; Bresell, Anders ; Sandberg, Martina ; Hennig, Klaus D. M. ; Wahren-Herlenius, Marie ; Persson, Bengt ; Sunnerhagen, Maria:
The Fellowship of the RING : The RING–B-Box Linker Region Interacts with the RING in TRIM21/Ro52, Contains a Native Autoantigenic Epitope in Sjögren Syndrome, and is an Integral and Conserved Region in TRIM Proteins.
In: Journal of Molecular Biology. Bd. 377 (2008) Heft 2 . - S. 431-449.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.01.005

Hennig, Janosch ; Hennig, Klaus D. M. ; Sunnerhagen, Maria:
MTMDAT : Automated analysis and visualization of mass spectrometry data for tertiary and quaternary structure probing of proteins.
In: Bioinformatics. Bd. 24 (2008) Heft 10 . - S. 1310-1312.
ISSN 1367-4803
DOI: https://doi.org/10.1093/bioinformatics/btn116

2006

Ottosson, Lars ; Hennig, Janosch ; Espinosa, Alexander ; Brauner, Susanna ; Wahren-Herlenius, Marie ; Sunnerhagen, Maria:
Structural, functional and immunologic characterization of folded subdomains in the Ro52 protein targeted in Sjögren's syndrome.
In: Molecular Immunology. Bd. 43 (2006) Heft 6 . - S. 588-598.
ISSN 0161-5890
DOI: https://doi.org/10.1016/j.molimm.2005.04.013

2005

Hennig, Janosch ; Ottosson, Lars ; Andrésen, Cecilia ; Horvath, Linn ; Kuchroo, Vijay K. ; Broo, Klas ; Wahren-Herlenius, Marie ; Sunnerhagen, Maria:
Structural Organization and Zn²⁺-dependent Subdomain Interactions Involving Autoantigenic Epitopes in the Ring-B-box-Coiled-coil (RBCC) Region of Ro52.
In: The Journal of Biological Chemistry. Bd. 280 (2005) Heft 39 . - S. 33250-33261.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M503066200

Ottosson, Lars ; Salomonsson, S. ; Hennig, Janosch ; Sonesson, S.-E. ; Dörner, T. ; Raats, J. ; Kuchroo, V. K. ; Sunnerhagen, Maria ; Wahren-Herlenius, Marie:
Structurally Derived Mutations Define Congenital Heart Block-Related Epitopes Within the 200-239 Amino Acid Stretch of the Ro52 Protein.
In: Scandinavian Journal of Immunology. Bd. 61 (2005) Heft 2 . - S. 109-118.
ISSN 1365-3083
DOI: https://doi.org/10.1111/j.0300-9475.2005.01542.x