Veröffentlichungen "Kuhn, Claus-D."

2023

Pittroff, Andreas ; Kim, Iana ; Kuhn, Claus-D.:
Genome-wide analysis of planarian piRNAs.
In: Gentile, Luca (Hrsg.): Schmidtea Mediterranea : Methods and Protocols. - New York : Humana Press , 2023 . - S. 55-65 . - (Methods in Molecular Biology ; 2680 )
ISBN 978-1-0716-3275-8
DOI: https://doi.org/10.1007/978-1-0716-3275-8_3

Kim, Iana ; Demtröder, Tim ; Kuhn, Claus-D.:
Isolation and library preparation of planarian piRNAs.
In: Gentile, Luca (Hrsg.): Schmidtea Mediterranea : Methods and Protocols. - New York : Humana Press , 2023 . - S. 29-54 . - (Methods in Molecular Biology ; 2680 )
ISBN 978-1-0716-3275-8
DOI: https://doi.org/10.1007/978-1-0716-3275-8_2

2022

Gorbovytska, Vladyslava ; Kim, Seung-Kyoon ; Kuybu, Filiz ; Götze, Michael ; Um, Dahun ; Kang, Keunsoo ; Pittroff, Andreas ; Brennecke, Theresia ; Schneider, Lisa-Marie ; Leitner, Alexander ; Kim, Tae-Kyung ; Kuhn, Claus-D.:
Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF.
In: Nature Communications. Bd. 13 (2022) . - 2429.
ISSN 2041-1723
DOI: https://doi.org/10.1038/s41467-022-29934-w

2021

Gorbovytska, Vladyslava ; Kim, Seung-Kyoon ; Kuybu, Filiz ; Götze, Michael ; Um, Dahun ; Kang, Keunsoo ; Pittroff, Andreas ; Schneider, Lisa-Marie ; Leitner, Alexander ; Kim, Tae-Kyung ; Kuhn, Claus-D.:
Enhancer RNAs stimulate Pol II pause release by harnessing multivalent interactions to NELF.
bioRxiv , 2021
DOI: https://doi.org/10.1101/2021.04.25.441328

2020

Rothemund, Matthias ; Bär, Alexander ; Klatt, Felix ; Weidler, Sascha ; Köhler, Leonhard ; Unverzagt, Carlo ; Kuhn, Claus-D. ; Schobert, Rainer:
N-Metallocenoylsphingosines as targeted ceramidase inhibitors : Syntheses and antitumoral effects.
In: Bioorganic Chemistry. Bd. 97 (2020) . - 103703.
ISSN 0045-2068
DOI: https://doi.org/10.1016/j.bioorg.2020.103703

Kim, Iana ; Riedelbauch, Sebastian ; Kuhn, Claus-D.:
The piRNA pathway in planarian flatworms : new model, new insights.
In: Biological Chemistry. Bd. 401 (2020) Heft 10 . - S. 1123-1141.
ISSN 1437-4315
DOI: https://doi.org/10.1515/hsz-2019-0445

Klatt, Felix ; Leitner, Alexander ; Kim, Iana ; Ho-Xuan, Hung ; Schneider, Elisabeth ; Langhammer, Franziska ; Weinmann, Robin ; Müller, Melanie ; Huber, Robert ; Meister, Gunter ; Kuhn, Claus-D.:
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 117 (2020) Heft 6 . - S. 2894-2905.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.1917635117

2019

Kim, Iana ; Ross, Eric ; Dietrich, Sascha ; Döring, Kristina ; Sánchez Alvarado, Alejandro ; Kuhn, Claus-D.:
Efficient depletion of ribosomal RNA for RNA sequencing in planarians.
In: BMC Genomics. Bd. 20 (2019) . - 909.
ISSN 1471-2164
DOI: https://doi.org/10.1186/s12864-019-6292-y

Kim, Iana ; Duncan, Elizabeth ; Ross, Eric ; Gorbovytska, Vladyslava ; Nowotarski, Stephanie ; Elliott, Sarah ; Sánchez Alvarado, Alejandro ; Kuhn, Claus-D.:
Planarians recruit piRNAs for mRNA turnover in adult stem cells.
In: Genes & Development. Bd. 33 (2019) Heft 21/22 . - S. 1575-1590.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.322776.118

2017

Kim, Iana ; Gorbovytska, Vladyslava ; Kuhn, Claus-D.:
Wie RNA die Genregulation beeinflusst.
In: BIOspektrum. Bd. 23 (2017) Heft 5 . - S. 513-515.
ISSN 1868-6249
DOI: https://doi.org/10.1007/s12268-017-0832-2

2016

Kuhn, Claus-D.:
RNA versatility governs tRNA function : Why tRNA flexibility is essential beyond the translation cycle.
In: BioEssays. Bd. 38 (2016) Heft 5 . - S. 465-473.
ISSN 1521-1878
DOI: https://doi.org/10.1002/bies.201500190

2015

Kostrewa, Dirk ; Kuhn, Claus-D. ; Engel, C. ; Cramer, Patrick:
An alternative RNA polymerase I structure reveals a dimer hinge.
In: Acta Crystallographica Section D. Bd. 71 (2015) Heft 9 . - S. 1850-1855.
ISSN 1399-0047
DOI: https://doi.org/10.1107/S1399004715012651

Kuhn, Claus-D. ; Wilusz, Jeremy E. ; Zheng, Yuxuan ; Beal, Peter A. ; Joshua-Tor, Leemor:
On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme.
In: Cell. Bd. 160 (2015) Heft 4 . - S. 644-658.
ISSN 1097-4172
DOI: https://doi.org/10.1016/j.cell.2015.01.005

2013

Kuhn, Claus-D. ; Joshua-Tor, Leemor:
Eukaryotic Argonautes come into focus.
In: Trends in Biochemical Sciences. Bd. 38 (2013) Heft 5 . - S. 263-271.
ISSN 0968-0004
DOI: https://doi.org/10.1016/j.tibs.2013.02.008

2012

Elkayam, Elad ; Kuhn, Claus-D. ; Tocilj, Ante ; Haase, Astrid D. ; Greene, Emily M. ; Hannon, Gregory J. ; Joshua-Tor, Leemor:
The structure of human argonaute-2 in complex with miR-20a.
In: Cell. Bd. 150 (2012) Heft 1 . - S. 100-110.
ISSN 1097-4172
DOI: https://doi.org/10.1016/j.cell.2012.05.017

Wilusz, Jeremy E. ; JnBaptiste, Courtney K. ; Lu, Laura Y. ; Kuhn, Claus-D. ; Joshua-Tor, Leemor ; Sharp, Phillip A.:
A triple helix stabilizes the 3' ends of long noncoding RNAs that lack poly(A) tails.
In: Genes & Development. Bd. 26 (2012) Heft 21 . - S. 2392-2407.
ISSN 1549-5477
DOI: https://doi.org/10.1101/gad.204438.112

2008

Geiger, Sebastian R. ; Kuhn, Claus-D. ; Leidig, Christoph ; Renkawitz, Jörg ; Cramer, Patrick:
Crystallization of RNA polymerase I subcomplex A14/A43 by iterative prediction, probing and removal of flexible regions.
In: Acta Crystallographica Section F. Bd. 64 (2008) Heft 5 . - S. 413-418.
ISSN 2053-230X
DOI: https://doi.org/10.1107/S174430910800972X

Gerber, Jochen ; Reiter, Alarich ; Steinbauer, Robert ; Jakob, Steffen ; Kuhn, Claus-D. ; Cramer, Patrick ; Griesenbeck, Joachim ; Milkereit, Philipp ; Tschochner, Herbert:
Site specific phosphorylation of yeast RNA polymerase I.
In: Nucleic Acids Research. Bd. 36 (2008) Heft 3 . - S. 793-802.
ISSN 1362-4962
DOI: https://doi.org/10.1093/nar/gkm1093

Cramer, Patrick ; Armache, Karim J. ; Baumli, Sonja ; Benkert, Stefan ; Brueckner, Florian ; Buchen, Claudia ; Damsma, Gerke E. ; Dengl, Stefan ; Geiger, Sebastian R. ; Jasiak, Anja J. ; Jawhari, Anass ; Jennebach, Stefan ; Kamenski, Tomislav ; Kettenberger, Hubert ; Kuhn, Claus-D. ; Lehmann, Elisabeth ; Leike, Kristin ; Sydow, Jasmin F. ; Vannini, Alessandro:
Structure of eukaryotic RNA polymerases.
In: Annual Review of Biophysics. Bd. 37 (2008) . - S. 337-352.
ISSN 1936-122X
DOI: https://doi.org/10.1146/annurev.biophys.37.032807.130008

2007

Kuhn, Claus-D. ; Geiger, Sebastian R. ; Baumli, Sonja ; Gartmann, Marco ; Gerber, Jochen ; Jennebach, Stefan ; Mielke, Thorsten ; Tschochner, Herbert ; Beckmann, Roland ; Cramer, Patrick:
Functional architecture of RNA polymerase I.
In: Cell. Bd. 131 (2007) Heft 7 . - S. 1260-1272.
ISSN 1097-4172
DOI: https://doi.org/10.1016/j.cell.2007.10.051

2006

Bhushan, Shashi ; Kuhn, Claus-D. ; Berglund, Anna-Karin ; Roth, Christian ; Glaser, Elzbieta:
The role of the N-terminal domain of chloroplast targeting peptides in organellar protein import and miss-sorting.
In: FEBS Letters. Bd. 580 (2006) Heft 16 . - S. 3966-3972.
ISSN 1873-3468
DOI: https://doi.org/10.1016/j.febslet.2006.06.018