Veröffentlichungen "Schmid, Franz X."

2015

Schmidpeter, Philipp A. M. ; Koch, Johanna R. ; Schmid, Franz X.:
Control of protein function by prolyl isomerization.
In: Biochimica et Biophysica Acta : General Subjects. Bd. 1850 (2015) Heft 10 . - S. 1973-1982.
ISSN 1872-8006
DOI: https://doi.org/10.1016/j.bbagen.2014.12.019

Jakob, Roman P. ; Koch, Johanna R. ; Burmann, Björn M. ; Schmidpeter, Philipp A. M. ; Hunkeler, Moritz ; Hiller, Sebastian ; Schmid, Franz X. ; Maier, Timm:
Dimeric Structure of the Bacterial Extracellular Foldase PrsA.
In: The Journal of Biological Chemistry. Bd. 290 (2015) Heft 6 . - S. 3278-3292.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M114.622910

Schmid, Franz X.:
How proteins knot their ties.
In: Journal of Molecular Biology. Bd. 427 (2015) Heft 2 . - S. 225-227.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2014.10.018

Schmidpeter, Philipp A. M. ; Schmid, Franz X.:
Prolyl isomerization as a molecular memory in the allosteric regulation of the signal adapter protein c-CrkII.
In: The Journal of Biological Chemistry. Bd. 290 (2015) Heft 5 . - S. 3021-3032.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M114.617308

Godin-Roulling, Amandine ; Schmidpeter, Philipp A. M. ; Schmid, Franz X. ; Feller, Georges:
Functional adaptations of the bacterial chaperone trigger factor to extreme environmental temperatures.
In: Environmental Microbiology. Bd. 17 (2015) Heft 7 . - S. 2407-2420.
ISSN 1462-2920
DOI: https://doi.org/10.1111/1462-2920.12707

2014

Hoffmann-Thoms, Stephanie ; Jakob, Roman P. ; Schmid, Franz X.:
Energetic communication between functional sites of the gene-3-protein during infection by phage fd.
In: Journal of Molecular Biology. Bd. 426 (2014) Heft 8 . - S. 1711-1722.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2014.01.002

Koch, Johanna R. ; Schmid, Franz X.:
Mia40 combines thiol oxidase and disulfide isomerase activity to efficiently catalyze oxidative folding in mitochondria.
In: Journal of Molecular Biology. Bd. 426 (2014) Heft 24 . - S. 4087-4098.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2014.10.022

Koch, Johanna R. ; Schmid, Franz X.:
Mia40 is optimized for function in mitochondrial oxidative protein folding and import.
In: ACS Chemical Biology. Bd. 9 (2014) Heft 9 . - S. 2049-2057.
ISSN 1554-8937
DOI: https://doi.org/10.1021/cb500408n

Koch, Johanna R. ; Schmid, Franz X.:
Mia40 targets cysteines in a hydrophobic environment to direct oxidative protein folding in the mitochondria.
In: Nature Communications. Bd. 5 (2014) . - 3041.
ISSN 2041-1723
DOI: https://doi.org/10.1038/ncomms4041

Schmidpeter, Philipp A. M. ; Schmid, Franz X.:
Molecular determinants of a regulatory prolyl isomerization in the signal adapter protein c-CrkII.
In: ACS Chemical Biology. Bd. 9 (2014) Heft 5 . - S. 1145-1152.
ISSN 1554-8937
DOI: https://doi.org/10.1021/cb500001n

Schmidpeter, Philipp A. M. ; Schmid, Franz X.:
Phosphorylation and prolyl isomerization independently regulate the signal adapter function of CrkII.
In: Journal of Molecular Biology. Bd. 426 (2014) Heft 24 . - S. 3929-3934.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2014.09.022

2013

Geitner, Anne-Juliane ; Varga, Edina ; Wehmer, Marc ; Schmid, Franz X.:
Generation of a highly active folding enzyme by combining a parvulin-type prolyl isomerase from SurA with an unrelated chaperone domain.
In: Journal of Molecular Biology. Bd. 425 (2013) Heft 22 . - S. 4089-4098.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2013.06.038

Hoffmann-Thoms, Stephanie ; Weininger, Ulrich ; Eckert, Barbara ; Jakob, Roman P. ; Koch, Johanna R. ; Balbach, Jochen ; Schmid, Franz X.:
Initiation of phage infection by partial unfolding and prolyl isomerization.
In: The Journal of Biological Chemistry. Bd. 288 (2013) Heft 18 . - S. 12979-12991.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.M112.442525

Kovermann, Michael ; Schmid, Franz X. ; Balbach, Jochen:
Molecular function of the prolyl cis/trans isomerase and metallochaperone SlyD.
In: Biological Chemistry. Bd. 394 (2013) Heft 8 . - S. 965-975.
ISSN 1437-4315
DOI: https://doi.org/10.1515/hsz-2013-0137

Zoldák, Gabriel ; Geitner, Anne-Juliane ; Schmid, Franz X.:
The prolyl isomerase SlyD is a highly efficient enzyme but decelerates the conformational folding of a client protein.
In: Journal of the American Chemical Society. Bd. 135 (2013) Heft 11 . - S. 4372-4379.
ISSN 1520-5126
DOI: https://doi.org/10.1021/ja311775a

Li, Jing ; Zoldák, Gabriel ; Kriehuber, Thomas ; Soroka, Joanna ; Schmid, Franz X. ; Richter, Klaus ; Buchner, Johannes:
Unique proline-rich domain regulates the chaperone function of AIPL1.
In: Biochemistry. Bd. 52 (2013) Heft 12 . - S. 2089-2096.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi301648q

Schriefer, Eva-Maria ; Hoffmann-Thoms, Stephanie ; Schmid, Franz X. ; Schmid, Annika ; Heesemann, Jürgen:
Yersinia enterocolitica and Photorhabdus asymbiotica β-lactamases BlaA are exported by the twin-arginine translocation pathway.
In: International Journal of Medical Microbiology. Bd. 303 (2013) Heft 1 . - S. 16-24.
ISSN 1618-0607
DOI: https://doi.org/10.1016/j.ijmm.2012.11.002

2012

Geitner, Anne-Juliane ; Schmid, Franz X.:
Combination of the human prolyl isomerase FKBP12 with unrelated chaperone domains leads to chimeric folding enzymes with high activity.
In: Journal of Molecular Biology. Bd. 420 (2012) Heft 4-5 . - S. 335-349.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2012.04.018

Carstensen, Linn ; Sperl, Josef M. ; Bocola, Marco ; List, Felix ; Schmid, Franz X. ; Sterner, Reinhard:
Conservation of the folding mechanism between designed primordial (βα)8-barrel proteins and their modern descendant.
In: Journal of the American Chemical Society. Bd. 134 (2012) Heft 30 . - S. 12786-12791.
ISSN 1520-5126
DOI: https://doi.org/10.1021/ja304951v

Carstensen, Linn ; Zoldák, Gabriel ; Schmid, Franz X. ; Sterner, Reinhard:
Folding mechanism of an extremely thermostable (βα)₈-barrel enzyme : a high kinetic barrier protects the protein from denaturation.
In: Biochemistry. Bd. 51 (2012) Heft 16 . - S. 3420-3432.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi300189f

Hoffmann-Thoms, Stephanie ; Schmid, Franz X.:
A kinetic approach to determining the conformational stability of a protein that dimerizes after folding.
In: Biochemistry. Bd. 51 (2012) Heft 18 . - S. 3948-3956.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi300154z

Jakob, Roman P. ; Geitner, Anne-Juliane ; Weininger, Ulrich ; Balbach, Jochen ; Dobbek, Holger ; Schmid, Franz X.:
Structural and energetic basis of infection by the filamentous bacteriophage IKe.
In: Molecular Microbiology. Bd. 84 (2012) Heft 6 . - S. 1124-1138.
ISSN 1365-2958
DOI: https://doi.org/10.1111/j.1365-2958.2012.08079.x

2011

Zoldák, Gabriel ; Schmid, Franz X.:
Cooperation of the prolyl isomerase and chaperone activities of the protein folding catalyst SlyD.
In: Journal of Molecular Biology. Bd. 406 (2011) Heft 1 . - S. 176-194.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2010.12.010

Lorenz, Stefan H. ; Jakob, Roman P. ; Weininger, Ulrich ; Balbach, Jochen ; Dobbek, Holger ; Schmid, Franz X.:
The filamentous phages fd and IF1 use different mechanisms to infect Escherichia coli.
In: Journal of Molecular Biology. Bd. 405 (2011) Heft 4 . - S. 989-1003.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2010.11.030

Schmid, Franz X.:
Lessons about protein stability from in vitro selections.
In: ChemBioChem. Bd. 12 (2011) Heft 10 . - S. 1501-1507.
ISSN 1439-7633
DOI: https://doi.org/10.1002/cbic.201100018

Schmidpeter, Philipp A. M. ; Jahreis, Günther ; Geitner, Anne-Juliane ; Schmid, Franz X.:
Prolyl isomerases show low sequence specificity toward the residue following the proline.
In: Biochemistry. Bd. 50 (2011) Heft 21 . - S. 4796-4803.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi200442q

Lorenz, Stefan H. ; Schmid, Franz X.:
Reprogramming the infection mechanism of a filamentous phage.
In: Molecular Microbiology. Bd. 80 (2011) Heft 3 . - S. 827-834.
ISSN 1365-2958
DOI: https://doi.org/10.1111/j.1365-2958.2011.07617.x

2010

Jakob, Roman P. ; Zierer, Bettina K. ; Weininger, Ulrich ; Hofmann, Stefanie D. ; Lorenz, Stefan H. ; Balbach, Jochen ; Dobbek, Holger ; Schmid, Franz X.:
Elimination of a cis-proline-containing loop and turn optimization stabilizes a protein and accelerates its folding.
In: Journal of Molecular Biology. Bd. 399 (2010) Heft 2 . - S. 331-346.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2010.04.007

Vandenameele, Julie ; Lejeune, Annabelle ; di Paolo, Alexandre ; Brans, Alain ; Frère, Jean-Marie ; Schmid, Franz X. ; Matagne, André:
Folding of class A beta-lactamases is rate-limited by peptide bond isomerization and occurs via parallel pathways.
In: Biochemistry. Bd. 49 (2010) Heft 19 . - S. 4264-4275.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi100369d

Buttstedt, Anja ; Winter, Reno ; Sackewitz, Mirko ; Hause, Gerd ; Schmid, Franz X. ; Schwarz, Elisabeth:
Influence of the stability of a fused protein and its distance to the amyloidogenic segment on fibril formation.
In: PLoS One. Bd. 5 (2010) Heft 11 . - No. e15436.
ISSN 1932-6203
DOI: https://doi.org/10.1371/journal.pone.0015436

Weininger, Ulrich ; Jakob, Roman P. ; Kovermann, Michael ; Balbach, Jochen ; Schmid, Franz X.:
The prolyl isomerase domain of PpiD from Escherichia coli shows a parvulin fold but is devoid of catalytic activity.
In: Protein Science. Bd. 19 (2010) Heft 1 . - S. 6-18.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.277

2009

Jakob, Roman P. ; Zoldák, Gabriel ; Aumüller, Tobias ; Schmid, Franz X.:
Chaperone domains convert prolyl isomerases into generic catalysts of protein folding.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 106 (2009) Heft 48 . - S. 20282-20287.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.0909544106

Zoldák, Gabriel ; Carstensen, Linn ; Scholz, Christian ; Schmid, Franz X.:
Consequences of domain insertion on the stability and folding mechanism of a protein.
In: Journal of Molecular Biology. Bd. 386 (2009) Heft 4 . - S. 1138-1152.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.12.052

Thoms, Stephanie ; Max, Klaas E. A. ; Wunderlich, Michael ; Jacso, Tomas ; Lilie, Hauke ; Reif, Bernd ; Heinemann, Udo ; Schmid, Franz X.:
Dimer formation of a stabilized Gβ1 variant : a structural and energetic analysis.
In: Journal of Molecular Biology. Bd. 391 (2009) Heft 5 . - S. 918-932.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2009.06.031

Zoldák, Gabriel ; Aumüller, Tobias ; Lücke, Christian ; Hritz, Jozef ; Oostenbrink, Chris ; Fischer, Gunter ; Schmid, Franz X.:
A library of fluorescent peptides for exploring the substrate specificities of prolyl isomerases.
In: Biochemistry. Bd. 48 (2009) Heft 43 . - S. 10423-10436.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi9014242

Jakob, Roman P. ; Schmid, Franz X.:
Molecular determinants of a native-state prolyl isomerization.
In: Journal of Molecular Biology. Bd. 387 (2009) Heft 4 . - S. 1017-1031.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2009.02.021

Weininger, Ulrich ; Haupt, Caroline ; Schweimer, Kristian ; Graubner, Wenke ; Kovermann, Michael ; Brüser, Thomas ; Scholz, Christian ; Schaarschmidt, Peter ; Zoldák, Gabriel ; Schmid, Franz X. ; Balbach, Jochen:
NMR solution structure of SlyD from Escherichia coli : spatial separation of prolyl isomerase and chaperone function.
In: Journal of Molecular Biology. Bd. 387 (2009) Heft 2 . - S. 295-305.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2009.01.034

Weininger, Ulrich ; Jakob, Roman P. ; Eckert, Barbara ; Schweimer, Kristian ; Schmid, Franz X. ; Balbach, Jochen:
A remote prolyl isomerization controls domain assembly via a hydrogen bonding network.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 106 (2009) Heft 30 . - 12335 -12340.
ISSN 1091-6490
DOI: https://doi.org/10.1073/pnas.0902102106

Piontek, Christian ; Ring, Petra ; Harjes, Olaf ; Heinlein, Christian ; Mezzato, Stefano ; Lombana Sanchez, Jose Nelson ; Pöhner, Claudia ; Püttner, Markus ; Varón Silva, Daniel ; Martin, Andreas ; Schmid, Franz X. ; Unverzagt, Carlo:
Semisynthesis of a homogeneous glycoprotein enzyme : ribonuclease C: part 1.
In: Angewandte Chemie International Edition. Bd. 48 (2009) Heft 11 . - S. 1936-1940.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.200804734

Piontek, Christian ; Varón Silva, Daniel ; Heinlein, Christian ; Pöhner, Claudia ; Mezzato, Stefano ; Ring, Petra ; Martin, Andreas ; Schmid, Franz X. ; Unverzagt, Carlo:
Semisynthesis of a homogeneous glycoprotein enzyme : ribonuclease C: part 2.
In: Angewandte Chemie International Edition. Bd. 48 (2009) Heft 11 . - S. 1941-1945.
ISSN 1521-3773
DOI: https://doi.org/10.1002/anie.200804735

2008

Kather, Insa ; Jakob, Roman P. ; Dobbek, Holger ; Schmid, Franz X.:
Changing the determinants of protein stability from covalent to non-covalent interactions by in vitro evolution : a structural and energetic analysis.
In: Journal of Molecular Biology. Bd. 381 (2008) Heft 4 . - S. 1040-1054.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.06.073

Scholz, Christian ; Thirault, Laurence ; Schaarschmidt, Peter ; Zarnt, Toralf ; Faatz, Elke ; Engel, Alfred M. ; Upmeier, Barbara ; Bollhagen, Ralf ; Eckert, Barbara ; Schmid, Franz X.:
Chaperone-aided in vitro renaturation of an engineered E1 envelope protein for detection of anti-Rubella virus IgG antibodies.
In: Biochemistry. Bd. 47 (2008) Heft 14 . - S. 4276-4287.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi702435v

Jakob, Roman P. ; Schmid, Franz X.:
Energetic coupling between native-state prolyl isomerization and conformational protein folding.
In: Journal of Molecular Biology. Bd. 377 (2008) Heft 5 . - S. 1560-1575.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.02.010

Sackewitz, Mirko ; von Einem, Sabrina ; Hause, Gerd ; Wunderlich, Michael ; Schmid, Franz X. ; Schwarz, Elisabeth:
A folded and functional protein domain in an amyloid-like fibril.
In: Protein Science. Bd. 17 (2008) Heft 6 . - S. 1044-1054.
ISSN 1469-896X
DOI: https://doi.org/10.1110/ps.073276308

Kather, Insa ; Jakob, Roman P. ; Dobbek, Holger ; Schmid, Franz X.:
Increased Folding Stability of TEM-1 β-Lactamase by In Vitro Selection.
In: Journal of Molecular Biology. Bd. 383 (2008) Heft 1 . - S. 238-251.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2008.07.082

Merkens, Hedda ; Kappl, Reinhard ; Jakob, Roman P. ; Schmid, Franz X. ; Fetzner, Susanne:
Quercetinase QueD of Streptomyces sp. FLA, a monocupin dioxygenase with a preference for nickel and cobalt.
In: Biochemistry. Bd. 47 (2008) Heft 46 . - S. 12185-12196.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi801398x

2007

Eckert, Barbara ; Schmid, Franz X.:
A conformational unfolding reaction activates phage fd for the infection of Escherichia coli.
In: Journal of Molecular Biology. Bd. 373 (2007) Heft 2 . - S. 452-461.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.07.060

Löw, Christian ; Weininger, Ulrich ; Zeeb, Markus ; Zhang, Wei ; Laue, Ernest D. ; Schmid, Franz X. ; Balbach, Jochen:
Folding mechanism of an ankyrin repeat protein : scaffold and active site formation of human CDK inhibitor p19(INK4d).
In: Journal of Molecular Biology. Bd. 373 (2007) Heft 1 . - S. 219-231.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.07.063

Knappe, Thomas A. ; Eckert, Barbara ; Schaarschmidt, Peter ; Scholz, Christian ; Schmid, Franz X.:
Insertion of a chaperone domain converts FKBP12 into a powerful catalyst of protein folding.
In: Journal of Molecular Biology. Bd. 368 (2007) Heft 5 . - S. 1458-1468.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.02.097

Wunderlich, Michael ; Max, Klaas E. A. ; Roske, Yvette ; Mueller, Uwe ; Heinemann, Udo ; Schmid, Franz X.:
Optimization of the Gβ1 domain by computational design and by in vitro evolution: structural and energetic basis of stabilization.
In: Journal of Molecular Biology. Bd. 373 (2007) Heft 3 . - S. 775-784.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.08.004

Max, Klaas E. A. ; Wunderlich, Michael ; Roske, Yvette ; Schmid, Franz X. ; Heinemann, Udo:
Optimized variants of the cold shock protein from in vitro selection : structural basis of their high thermostability.
In: Journal of Molecular Biology. Bd. 369 (2007) Heft 4 . - S. 1087-1097.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2007.04.016

2006

Wunderlich, Michael ; Schmid, Franz X.:
The correlation between protein stability and dipole moment : a critical test.
In: Protein Engineering, Design & Selection. Bd. 19 (2006) Heft 8 . - S. 355-358.
ISSN 1741-0134
DOI: https://doi.org/10.1093/protein/gzl019

Wunderlich, Michael ; Schmid, Franz X.:
In vitro evolution of a hyperstable Gbeta1 variant.
In: Journal of Molecular Biology. Bd. 363 (2006) Heft 2 . - S. 545-557.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2006.08.034

Garcia-Mira, Maria M. ; Schmid, Franz X.:
Key role of coulombic interactions for the folding transition state of the cold shock protein.
In: Journal of Molecular Biology. Bd. 364 (2006) Heft 3 . - S. 458-468.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2006.08.071

Eckert, Barbara ; Schmid, Franz X.:
Prolin als molekularer Schalter.
In: BIOspektrum. Bd. 12 (2006) Heft 2 . - S. 151-153.
ISSN 1868-6249

Scholz, Christian ; Eckert, Barbara ; Hagn, Franz ; Schaarschmidt, Peter ; Balbach, Jochen ; Schmid, Franz X.:
SlyD proteins from different species exhibit high prolyl isomerase and chaperone activities.
In: Biochemistry. Bd. 45 (2006) Heft 1 . - S. 20-33.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi051922n

Magg, Christine ; Kubelka, Jan ; Holtermann, Georg ; Haas, Elisha ; Schmid, Franz X.:
Specificity of the initial collapse in the folding of the cold shock protein.
In: Journal of Molecular Biology. Bd. 360 (2006) Heft 5 . - S. 1067-1080.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2006.05.073

2005

Wunderlich, Michael ; Martin, Andreas ; Staab, Claudia A. ; Schmid, Franz X.:
Evolutionary protein stabilization in comparison with computational design.
In: Journal of Molecular Biology. Bd. 351 (2005) Heft 5 . - S. 1160-1168.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2005.06.059

Scholz, Christian ; Schaarschmidt, Peter ; Engel, Alfred M. ; Andres, Herbert ; Schmitt, Urban ; Faatz, Elke ; Balbach, Jochen ; Schmid, Franz X.:
Functional solubilization of aggregation-prone HIV envelope proteins by covalent fusion with chaperone modules.
In: Journal of Molecular Biology. Bd. 345 (2005) Heft 5 . - S. 1229-1241.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2004.10.091

Eckert, Barbara ; Martin, Andreas ; Balbach, Jochen ; Schmid, Franz X.:
Prolyl isomerization as a molecular timer in phage infection.
In: Nature Structural & Molecular Biology. Bd. 12 (2005) Heft 7 . - S. 619-623.
ISSN 1545-9985
DOI: https://doi.org/10.1038/nsmb946

Schmid, Franz X.:
Prolyl isomerization in protein folding.
In: Buchner, Johannes ; Kiefhaber, Thomas (ed.): Protein Folding Handbook, Part I. - Weinheim : Wiley-VCH , 2005 . - S. 916-945
ISBN 978-3-527-30784-5
DOI: https://doi.org/10.1002/9783527619498.ch25

Schmid, Franz X.:
Spectroscopic techniques to study protein folding an d stability.
In: Buchner, Johannes ; Kiefhaber, Thomas (ed.): Protein Folding Handbook, Part I. - Weinheim : Wiley-VCH , 2005 . - S. 22-44
ISBN 978-3-527-30784-5
DOI: https://doi.org/10.1002/9783527619498.ch2

Wunderlich, Michael ; Martin, Andreas ; Schmid, Franz X.:
Stabilization of the cold shock protein CspB from Bacillus subtilis by evolutionary optimization of Coulombic interactions.
In: Journal of Molecular Biology. Bd. 347 (2005) Heft 5 . - S. 1063-1076.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2005.02.014

Kather, Insa ; Bippes, Christian A. ; Schmid, Franz X.:
A stable disulfide-free gene-3-protein of phage fd generated by in vitro evolution.
In: Journal of Molecular Biology. Bd. 354 (2005) Heft 3 . - S. 666-678.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2005.09.086

2004

Garcia-Mira, Maria M. ; Boehringer, Daniel ; Schmid, Franz X.:
The folding transition state of the cold shock protein is strongly polarized.
In: Journal of Molecular Biology. Bd. 339 (2004) Heft 3 . - S. 555-569.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2004.04.011

Magg, Christine ; Schmid, Franz X.:
Rapid collapse precedes the fast two-state folding of the cold shock protein.
In: Journal of Molecular Biology. Bd. 335 (2004) Heft 5 . - S. 1309-1323.
ISSN 0022-2836
DOI: https://doi.org/10.1016/j.jmb.2003.11.050

Sterner, Reinhard ; Schmid, Franz X.:
De novo design of an enzyme.
In: Science. Bd. 304 (2004) Heft 5679 . - S. 1916-1917.
ISSN 1095-9203
DOI: https://doi.org/10.1126/science.1100482

2003

Martin, Andreas ; Schmid, Franz X.:
Evolutionary stabilization of the gene-3-protein of phage fd reveals the principles that govern the thermodynamic stability of two-domain proteins.
In: Journal of Molecular Biology. Bd. 328 (2003) Heft 4 . - S. 863-875.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(03)00359-0

Martin, Andreas ; Schmid, Franz X.:
The folding mechanism of a two-domain protein : folding kinetics and domain docking of the gene-3 protein of phage fd.
In: Journal of Molecular Biology. Bd. 329 (2003) Heft 3 . - S. 599-610.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(03)00433-9

Maier, Raimund ; Eckert, Barbara ; Scholz, Christian ; Lilie, Hauke ; Schmid, Franz X.:
Interaction of trigger factor with the ribosome.
In: Journal of Molecular Biology. Bd. 326 (2003) Heft 2 . - S. 585-592.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(02)01427-4

Martin, Andreas ; Schmid, Franz X.:
A proline switch controls folding and domain interactions in the gene-3-protein of the filamentous phage fd.
In: Journal of Molecular Biology. Bd. 331 (2003) Heft 5 . - S. 1131-1140.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(03)00864-7

Martin, Andreas ; Schmid, Franz X. ; Sieber, Volker:
Proside : a phage-based method for selecting thermostable proteins.
In: Arnold, Frances H. ; Georgiou, George (Hrsg.): Directed enzyme evolution : screening and selection methods. - Totowa, NJ : Humana Press , 2003 . - S. 57-70 . - (Methods in Molecular Biology ; 230 )
ISBN 978-1-61737-472-2
DOI: https://doi.org/10.1385/1-59259-396-8:57

2002

Dominy, Brian N. ; Perl, Dieter ; Schmid, Franz X. ; Brooks, Charles L.:
The effects of ionic strength on protein stability : the cold shock protein family.
In: Journal of Molecular Biology. Bd. 319 (2002) Heft 2 . - S. 541-554.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(02)00259-0

Schiene-Fischer, Cordelia ; Habazettl, Judith ; Schmid, Franz X. ; Fischer, Gunter:
The hsp70 chaperone DnaK is a secondary amide peptide bond cis-trans isomerase.
In: Nature Structural & Molecular Biology. Bd. 9 (2002) Heft 6 . - S. 419-424.
ISSN 1545-9985
DOI: https://doi.org/10.1038/nsb804

Martin, Andreas ; Kather, Insa ; Schmid, Franz X.:
Origins of the high stability of an in vitro-selected cold-shock protein.
In: Journal of Molecular Biology. Bd. 318 (2002) Heft 5 . - S. 1341-1349.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(02)00243-7

Perl, Dieter ; Schmid, Franz X.:
Some like it hot : the molecular determinants of protein thermostability.
In: ChemBioChem. Bd. 3 (2002) Heft 1 . - S. 39-44.
ISSN 1439-7633
DOI: https://doi.org/10.1002/1439-7633(20020104)3:1<39::AID-CBIC39>3.0.CO;2-D

Perl, Dieter ; Jacob, Maik H. ; Bánó, Mikulás ; Stupák, Marek ; Antalík, Marián ; Schmid, Franz X.:
Thermodynamics of a diffusional protein folding reaction.
In: Biophysical Chemistry. Bd. 96 (2002) Heft 2-3 . - S. 173-190.
ISSN 1873-4200
DOI: https://doi.org/10.1016/S0301-4622(02)00024-8

Jacob, Maik H. ; Saudan, Christophe ; Holtermann, Georg ; Martin, Andreas ; Perl, Dieter ; Merbach, André E. ; Schmid, Franz X.:
Water contributes actively to the rapid crossing of a protein unfolding barrier.
In: Journal of Molecular Biology. Bd. 318 (2002) Heft 3 . - S. 837-845.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(02)00165-1

2001

Schindler, Ilka ; Renz, Andreas ; Schmid, Franz X. ; Beck, Erwin:
Activation of spinach pullulanase by reduction results in a decrease in the number of isomeric forms.
In: Biochimica et Biophysica Acta : Protein Structure and Molecular Enzymology. Bd. 1548 (2001) Heft 2 . - S. 175-186.
ISSN 0167-4838
DOI: https://doi.org/10.1016/S0167-4838(01)00228-X

Schmid, Franz X.:
Biological macromolecules : UV-visible spectrophotometry.
In: Encyclopedia of Life Sciences : eLS. - London, UK : Macmillan Press , 2001
DOI: https://doi.org/10.1038/npg.els.0003142

Delbrück, Heinrich ; Mueller, Uwe ; Perl, Dieter ; Schmid, Franz X. ; Heinemann, Udo:
Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.
In: Journal of Molecular Biology. Bd. 313 (2001) Heft 2 . - S. 359-369.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.2001.5051

Maier, Raimund ; Scholz, Christian ; Schmid, Franz X.:
Dynamic association of trigger factor with protein substrates.
In: Journal of Molecular Biology. Bd. 314 (2001) Heft 5 . - S. 1181-1190.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.2000.5192

Perl, Dieter ; Schmid, Franz X.:
Electrostatic stabilization of a thermophilic cold shock protein.
In: Journal of Molecular Biology. Bd. 313 (2001) Heft 2 . - S. 343-357.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.2001.5050

Martin, Andreas ; Sieber, Volker ; Schmid, Franz X.:
In-vitro selection of highly stabilized protein variants with optimized surface.
In: Journal of Molecular Biology. Bd. 309 (2001) Heft 3 . - S. 717-726.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.2001.4698

Fischer, Gunter ; Schmid, Franz X.:
Peptidylproline cis-trans isomerases.
In: Encyclopedia of Life Sciences : eLS. - London, UK : Macmillan Press , 2001
DOI: https://doi.org/10.1038/npg.els.0003020

Schmid, Franz X.:
Prolyl isomerases.
In: Advances in Protein Chemistry. Bd. 59 (2001) . - S. 243-282.
ISSN 0065-3233
DOI: https://doi.org/10.1016/S0065-3233(01)59008-7

Perl, Dieter ; Holtermann, Georg ; Schmid, Franz X.:
Role of the chain termini for the folding transition state of the cold shock protein.
In: Biochemistry. Bd. 40 (2001) Heft 51 . - S. 15501-15511.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi011378s

Behrens, Susanne ; Maier, Raimund ; de Cock, Hans ; Schmid, Franz X. ; Gross, Carol A.:
The SurA periplasmic PPIase lacking its parvulin domains functions in vivo and has chaperone activity.
In: The EMBO Journal. Bd. 20 (2001) Heft 1-2 . - S. 285-294.
ISSN 1460-2075
DOI: https://doi.org/10.1093/emboj/20.1.285

2000

Balbach, Jochen ; Schmid, Franz X.:
Prolyl isomerization and its catalysis in protein folding.
In: Pain, Roger H. (ed.): Mechanisms of Protein Folding : Frontiers in Molecular Biology. 2nd ed. - Oxford, UK : Oxford University Press , 2000 . - S. 212-249 . - (Frontiers in Molecular Biology ; 32 )
ISBN 0-19-963789-X

Mueller, Uwe ; Perl, Dieter ; Schmid, Franz X. ; Heinemann, Udo:
Thermal stability and atomic-resolution crystal structure of the Bacillus caldolyticus cold shock protein.
In: Journal of Molecular Biology. Bd. 297 (2000) Heft 4 . - S. 975-988.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.2000.3602

Perl, Dieter ; Mueller, Uwe ; Heinemann, Udo ; Schmid, Franz X.:
Two exposed amino acid residues confer thermostability on a cold shock protein.
In: Nature Structural Biology. Bd. 7 (2000) Heft 5 . - S. 380-383.
ISSN 1072-8368
DOI: https://doi.org/10.1038/75151

1999

Bukau, Bernd ; Schmid, Franz X. ; Buchner, Johannes:
Assisted protein folding.
In: Bukau, Bernd (Hrsg.): Molecular Chaperones and Folding Catalysts : regulation, cellular function, and mechanisms. - New York : Harwood Academic Publishers , 1999 . - S. 3-10
ISBN 90-5702-370-9

Jacob, Maik H. ; Geeves, Michael A. ; Holtermann, Georg ; Schmid, Franz X.:
Diffusional barrier crossing in a two-state protein folding reaction.
In: Nature Structural Biology. Bd. 6 (1999) Heft 10 . - S. 923-926.
ISSN 1072-8368
DOI: https://doi.org/10.1038/13289

Schindler, Thomas ; Graumann, Peter L. ; Perl, Dieter ; Ma, Saufung ; Schmid, Franz X. ; Marahiel, Mohamed A.:
The family of cold shock proteins of Bacillus subtilis : Stability and dynamics in vitro and in vivo.
In: The Journal of Biological Chemistry. Bd. 274 (1999) Heft 6 . - S. 3407-3413.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.274.6.3407

Jacob, Maik H. ; Holtermann, Georg ; Perl, Dieter ; Reinstein, Jochen ; Schindler, Thomas ; Geeves, Michael A. ; Schmid, Franz X.:
Microsecond folding of the cold shock protein measured by a pressure-jump technique.
In: Biochemistry. Bd. 38 (1999) Heft 10 . - S. 2882-2891.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi982487i

Fischer, Gunter ; Schmid, Franz X.:
Peptidyl-prolyl cis/trans isomerases.
In: Bukau, Bernd (Hrsg.): Molecular Chaperones and Folding Catalysts : regulation, cellular function, and mechanisms. - New York : Harwood Academic Publishers , 1999 . - S. 461-489
ISBN 90-5702-370-9

Schmid, Franz X.:
Protein Folding.
In: Allen, Geoffrey (ed.): Protein : A Comprehensive Treatise. Vol. 2. - Greenwich, Connecticut : JAI Press , 1999 . - S. 153-215
ISBN 1-55938-672-X

Jacob, Maik H. ; Schmid, Franz X.:
Protein folding as a diffusional process.
In: Biochemistry. Bd. 38 (1999) Heft 42 . - S. 13773-13779.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi991503o

Balbach, Jochen ; Steegborn, Clemens ; Schindler, Thomas ; Schmid, Franz X.:
A protein folding intermediate of ribonuclease T₁ characterized at high resolution by 1D and 2D real-time NMR spectroscopy.
In: Journal of Molecular Biology. Bd. 285 (1999) Heft 2 . - S. 829-842.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1998.2364

Scholz, Christian ; Maier, Peter ; Dolinski, Kara ; Heitman, Joseph ; Schmid, Franz X.:
R73A and H144Q mutants of the yeast mitochondrial cyclophilin Cpr3 exhibit a low prolyl isomerase activity in both peptide and protein-folding assays.
In: FEBS Letters. Bd. 443 (1999) Heft 3 . - S. 367-369.
ISSN 1873-3468
DOI: https://doi.org/10.1016/S0014-5793(98)01735-9

Schmid, Franz X.:
Spectroscopy.
In: Creighton, Thomas E. (ed.): The Encyclopedia of Molecular Biology. Vol. 4. - New York : John Wiley & Sons , 1999
ISBN 0-471-16644-8

1998

Schmid, Franz X.:
Catalysis of protein folding by prolyl isomerases.
In: Fink, Anthony L. ; Goto, Y. (Hrsg.): Molecular chaperones in the Life Cycle of Proteins. - New York : Dekker , 1998 . - S. 361-389
ISBN 0-8247-0100-3

Schindler, Thomas ; Perl, Dieter ; Graumann, Peter L. ; Sieber, Volker ; Marahiel, Mohamed A. ; Schmid, Franz X.:
Surface-exposed phenylalanines in the RNP1/RNP2 motif stabilize the cold-shock protein CspB from Bacillus subtilis.
In: Proteins. Bd. 30 (1998) Heft 4 . - S. 401-406.
ISSN 1097-0134
DOI: https://doi.org/10.1002/(SICI)1097-0134(19980301)30:4<401::AID-PROT7>3.0.CO;2-L

1997

Backes, Heike ; Berens, Christian ; Helbl, Vera ; Walter, Stefan ; Schmid, Franz X. ; Hillen, Wolfgang:
Combinations of the alpha-helix-turn-alpha-helix motif of TetR with respective residues from LacI or 434Cro : DNA recognition, inducer binding, and urea-dependent denaturation.
In: Biochemistry. Bd. 36 (1997) Heft 18 . - S. 5311-5322.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi961527k

Scholz, Christian ; Stoller, Gerlind ; Zarnt, Toralf ; Fischer, Gunter ; Schmid, Franz X.:
Cooperation of enzymatic and chaperone functions of trigger factor in the catalysis of protein folding.
In: The EMBO Journal. Bd. 16 (1997) Heft 1 . - S. 54-58.
ISSN 1460-2075
DOI: https://doi.org/10.1093/emboj/16.1.54

Scholz, Christian ; Schindler, Thomas ; Dolinski, Kara ; Heitman, Joseph ; Schmid, Franz X.:
Cyclophilin active site mutants have native prolyl isomerase activity with a protein substrate.
In: FEBS Letters. Bd. 414 (1997) Heft 1 . - S. 69-73.
ISSN 1873-3468
DOI: https://doi.org/10.1016/S0014-5793(97)00979-4

Jacob, Maik H. ; Schindler, Thomas ; Balbach, Jochen ; Schmid, Franz X.:
Diffusion control in an elementary protein folding reaction.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 94 (1997) Heft 11 . - S. 5622-5627.
ISSN 1091-6490

Mogk, Axel ; Homuth, Georg ; Scholz, Christian ; Kim, Lana ; Schmid, Franz X. ; Schumann, Wolfgang:
The GroE chaperonin machine is a major modulator of the CIRCE heat shock regulon of Bacillus subtilis.
In: The EMBO Journal. Bd. 16 (1997) Heft 15 . - S. 4579-4590.
ISSN 1460-2075
DOI: https://doi.org/10.1093/emboj/16.15.4579

Schmid, Franz X. ; Pace, C. N.:
How to determine the molar absorption coefficient of a protein.
In: Creighton, Thomas E. (ed.): Protein Structure: a Practical Approach. 2. ed. - Oxford : IRL press , 1997 . - S. 253-259 . - (The Practical Approach Series ; 174 )
ISBN 0-19-963619-2

Zarnt, Toralf ; Tradler, Thomas ; Stoller, Gerlind ; Scholz, Christian ; Schmid, Franz X. ; Fischer, Gunter:
Modular structure of the trigger factor required for high activity in protein folding.
In: Journal of Molecular Biology. Bd. 271 (1997) Heft 5 . - S. 827-837.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1997.1206

Schmid, Franz X.:
Spectral methods of characterizing protein conformation and conformational changes.
In: Creighton, Thomas E. (ed.): Protein Structure: a Practical Approach. 2. ed. - Oxford : IRL press , 1997 . - S. 261-297 . - (The Practical Approach Series ; 174 )
ISBN 0-19-963619-2

Agashe, Vishwas R. ; Schmid, Franz X. ; Udgaonkar, Jayant B.:
Thermodynamics of the complex protein unfolding reaction of barstar.
In: Biochemistry. Bd. 36 (1997) Heft 40 . - S. 12288-12295.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi971062d

Schmid, Franz X. ; Bukau, Bernd:
Trendbericht 1996: Proteinfaltung.
In: Nachrichten aus Chemie, Technik und Laboratorium. Bd. 45 (1997) . - S. 166-169.
ISSN 0341-5163

1996

Scholz, Christian ; Zarnt, Toralf ; Kern, Gunther ; Lang, Karl ; Burtscher, Helmut ; Fischer, Gunter ; Schmid, Franz X.:
Autocatalytic folding of the folding catalyst FKBP12.
In: The Journal of Biological Chemistry. Bd. 271 (1996) Heft 22 . - S. 12703-12707.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.271.22.12703

Schmid, Franz X. ; Frech, Christian ; Scholz, Christian ; Walter, Stefan:
Catalyzed and assisted protein folding of ribonuclease T1.
In: Biological Chemistry. Bd. 377 (1996) Heft 7-8 . - S. 417-424.
ISSN 1437-4315

Frech, Christian ; Wunderlich, Martina ; Glockshuber, Rudi ; Schmid, Franz X.:
Competition between DsbA-mediated oxidation and conformational folding of RTEM1 beta-lactamase.
In: Biochemistry. Bd. 35 (1996) Heft 35 . - S. 11386-11395.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi9608525

Mayr, Lorenz M. ; Odefey, C. ; Schutkowski, Mike ; Schmid, Franz X.:
Kinetic analysis of the unfolding and refolding of ribonuclease T1 by a stopped-flow double-mixing technique.
In: Biochemistry. Bd. 35 (1996) Heft 17 . - S. 5550-5561.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi953035y

Frech, Christian ; Wunderlich, Martina ; Glockshuber, Rudi ; Schmid, Franz X.:
Preferential binding of an unfolded protein to DsbA.
In: The EMBO Journal. Bd. 15 (1996) Heft 2 . - S. 392-398.
ISSN 1460-2075

Schindler, Thomas ; Mayr, Lorenz M. ; Landt, Olfert ; Hahn, Ulrich ; Schmid, Franz X.:
The role of a trans-proline in the folding mechanism of ribonuclease T1.
In: European Journal of Biochemistry. Bd. 241 (1996) Heft 2 . - S. 516-524.
ISSN 0014-2956
DOI: https://doi.org/10.1111/j.1432-1033.1996.00516.x

Walter, Stefan ; Lorimer, George H. ; Schmid, Franz X.:
A thermodynamic coupling mechanism for GroEL-mediated unfolding.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 93 (1996) Heft 18 . - S. 9425-9430.
ISSN 1091-6490

Schindler, Thomas ; Schmid, Franz X.:
Thermodynamic properties of an extremely rapid protein folding reaction.
In: Biochemistry. Bd. 35 (1996) Heft 51 . - S. 16833-16842.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi962090j

1995

Walter, Stefan ; Hubner, Bernd ; Hahn, Ulrich ; Schmid, Franz X.:
Destabilization of a protein helix by electrostatic interactions.
In: Journal of Molecular Biology. Bd. 252 (1995) Heft 1 . - S. 133-143.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1995.0480

Frech, Christian ; Schmid, Franz X.:
DsbA-mediated disulfide bond formation and catalyzed prolyl isomerization in oxidative protein folding.
In: The Journal of Biological Chemistry. Bd. 270 (1995) Heft 10 . - S. 5367-5374.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.270.10.5367

Schindler, Thomas ; Herrler, Michael ; Marahiel, Mohamed A. ; Schmid, Franz X.:
Extremely rapid protein folding in the absence of intermediates.
In: Nature Structural & Molecular Biology. Bd. 2 (1995) Heft 8 . - S. 663-673.
ISSN 1545-9985
DOI: https://doi.org/10.1038/nsb0895-663

Frech, Christian ; Schmid, Franz X.:
Influence of protein conformation on disulfide bond formation in the oxidative folding of ribonuclease T₁.
In: Journal of Molecular Biology. Bd. 251 (1995) Heft 1 . - S. 135-149.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1995.0421

Kern, Gunther ; Kern, Dorothee ; Schmid, Franz X. ; Fischer, Gunter:
A kinetic analysis of the folding of human carbonic anhydrase II and its catalysis by cyclophilin.
In: The Journal of Biological Chemistry. Bd. 270 (1995) Heft 2 . - S. 740-745.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.270.2.740

Odefey, C. ; Mayr, Lorenz M. ; Schmid, Franz X.:
Non-prolyl cis-trans peptide bond isomerization as a rate-determining step in protein unfolding and refolding.
In: Journal of Molecular Biology. Bd. 245 (1995) Heft 1 . - S. 69-78.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(95)80039-5

Schmid, Franz X.:
Protein folding : Prolyl isomerases join the fold.
In: Current Biology. Bd. 5 (1995) Heft 9 . - S. 993-994.
ISSN 1879-0445
DOI: https://doi.org/10.1016/S0960-9822(95)00197-7

Stoller, Gerlind ; Rücknagel, K. Peter ; Nierhaus, Knud H. ; Schmid, Franz X. ; Fischer, Gunter ; Rahfeld, Jens-U.:
A ribosome-associated peptidyl-prolyl cis/trans isomerase identified as the trigger factor.
In: The EMBO Journal. Bd. 14 (1995) Heft 20 . - S. 4939-4948.
ISSN 1460-2075

Marx, Ute C. ; Austermann, Sabine ; Bayer, Peter ; Adermann, Knut ; Ejchart, Andrzej ; Sticht, Heinrich ; Walter, Stefan ; Schmid, Franz X. ; Jaenicke, Rainer ; Forssmann, Wolf-Georg ; Rösch, Paul:
Structure of human parathyroid hormone 1-37 in solution.
In: The Journal of Biological Chemistry. Bd. 270 (1995) Heft 25 . - S. 15194-15202.
ISSN 1083-351X
DOI: https://doi.org/10.1074/jbc.270.25.15194

1994

Mücke, Matthias ; Schmid, Franz X.:
Folding mechanism of ribonuclease T1 in the absence of the disulfide bonds.
In: Biochemistry. Bd. 33 (1994) Heft 48 . - S. 14608-14619.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00252a029

Mayr, Lorenz M. ; Willbold, Dieter ; Rösch, Paul ; Schmid, Franz X.:
Generation of a non-prolyl cis peptide bond in ribonuclease T1.
In: Journal of Molecular Biology. Bd. 240 (1994) Heft 4 . - S. 288-293.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1994.1446

Mücke, Matthias ; Schmid, Franz X.:
Intact disulfide bonds decelerate the folding of ribonuclease T1.
In: Journal of Molecular Biology. Bd. 239 (1994) Heft 5 . - S. 713-725.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1994.1408

Mücke, Matthias ; Schmid, Franz X.:
A kinetic method to evaluate the two-state character of solvent-induced protein denaturation.
In: Biochemistry. Bd. 33 (1994) Heft 43 . - S. 12930-12935.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00209a025

Schmid, Franz X. ; Kiefhaber, Thomas ; Mayr, Lorenz M.:
Prolyl isomerizations as rate-determing steps in the folding of ribonuclease T1.
In: Friedel, Jacques ; Gros, François (Hrsg.): Organisation et processus dans les systèmes biologiques. - Paris : Tec et Doc , 1994 . - S. 87-93 . - (Actes de Colloques / Académie des Sciences, Paris )
ISBN 2743000023

Kern, Gunther ; Kern, Dorothee ; Schmid, Franz X. ; Fischer, Gunter:
Reassessment of the putative chaperone function of prolyl-cis/trans-isomerases.
In: FEBS Letters. Bd. 348 (1994) Heft 2 . - S. 145-148.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(94)00591-5

Mayr, Lorenz M. ; Willbold, Dieter ; Landt, Olfert ; Schmid, Franz X.:
Role of the Cys 2-Cys 10 disulfide bond for the structure, stability, and folding kinetics of ribonuclease T1.
In: Protein Science. Bd. 3 (1994) Heft 2 . - S. 227-239.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.5560030207

1993

Mayr, Lorenz M. ; Schmid, Franz X.:
Kinetic models for unfolding and refolding of ribonuclease T₁ with substitution of cis-proline 39 by alanine.
In: Journal of Molecular Biology. Bd. 231 (1993) Heft 3 . - S. 913-926.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1993.1337

Schmid, Franz X.:
Prolyl isomerase : enzymatic catalysis of slow protein-folding reactions.
In: Annual Review of Biophysics and Biomolecular Structure. Bd. 22 (1993) . - S. 123-142.
ISSN 1056-8700
DOI: https://doi.org/10.1146/annurev.bb.22.060193.001011

Schmid, Franz X. ; Mayr, Lorenz M. ; Mücke, Matthias ; Schönbrunner, Erhard Ralf:
Prolyl isomerases : role in protein folding.
In: Advances in Protein Chemistry. Bd. 44 (1993) . - S. 25-66.
ISSN 0065-3233
DOI: https://doi.org/10.1016/S0065-3233(08)60563-X

Schmid, Franz X. ; Kiefhaber, Thomas ; Mayr, Lorenz M.:
Prolyl isomerizations as rate-determing steps in the folding of ribonuclease T1.
In: Cleland, Jeffrey L. (Hrsg.): Protein Folding : in vivo and in vitro. - Washington, DC : ACS , 1993 . - S. 142-155 . - (ACS Symposium Series ; 526 )
ISBN 0-8412-2640-7

Mayr, Lorenz M. ; Schmid, Franz X.:
A purification method for labile variants of ribonuclease T1.
In: Protein Expression and Purification. Bd. 4 (1993) Heft 1 . - S. 52-58.
ISSN 1046-5928
DOI: https://doi.org/10.1006/prep.1993.1008

Mayr, Lorenz M. ; Landt, Olfert ; Hahn, Ulrich ; Schmid, Franz X.:
Stability and folding kinetics of ribonuclease T₁ are strongly altered by the replacement of cis-proline 39 with alanine.
In: Journal of Molecular Biology. Bd. 231 (1993) Heft 3 . - S. 897-912.
ISSN 0022-2836
DOI: https://doi.org/10.1006/jmbi.1993.1336

Mayr, Lorenz M. ; Schmid, Franz X.:
Stabilization of a protein by guanidinium chloride.
In: Biochemistry. Bd. 32 (1993) Heft 31 . - S. 7994-7998.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00082a021

1992

Schultz, David A. ; Schmid, Franz X. ; Baldwin, Robert L.:
Cis proline mutants of ribonuclease A. II. Elimination of the slow-folding forms by mutation.
In: Protein Science. Bd. 1 (1992) Heft 7 . - S. 917-924.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.5560010710

Mücke, Matthias ; Schmid, Franz X.:
Enzymatic catalysis of prolyl isomerization in an unfolding protein.
In: Biochemistry. Bd. 31 (1992) Heft 34 . - S. 7848-7854.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00149a015

Kiefhaber, Thomas ; Grunert, Hans Peter ; Hahn, Ulrich ; Schmid, Franz X.:
Folding of RNase T1 is decelerated by a specific tertiary contact in a folding intermediate.
In: Proteins. Bd. 12 (1992) Heft 2 . - S. 171-179.
ISSN 1097-0134
DOI: https://doi.org/10.1002/prot.340120210

Kiefhaber, Thomas ; Kohler, Hans-Helmut ; Schmid, Franz X.:
Kinetic coupling between protein folding and prolyl isomerization. I. Theoretical models.
In: Journal of Molecular Biology. Bd. 224 (1992) Heft 1 . - S. 217-229.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(92)90585-8

Kiefhaber, Thomas ; Schmid, Franz X.:
Kinetic coupling between protein folding and prolyl isomerization. II. Folding of ribonuclease A and ribonuclease T₁.
In: Journal of Molecular Biology. Bd. 224 (1992) Heft 1 . - S. 231-240.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(92)90586-9

Schmid, Franz X.:
Kinetics of unfolding and refolding of single-domain proteins.
In: Creighton, Thomas E. (Hrsg.): Protein Folding. - New York : Freeman , 1992 . - S. 197-241
ISBN 0-7167-7027-X

Schmid, Franz X.:
The mechanism of protein folding.
In: Current Opinion in Structural Biology. Bd. 2 (1992) Heft 1 . - S. 21-25.
ISSN 0959-440X
DOI: https://doi.org/10.1016/0959-440X(92)90171-3

Schönbrunner, Erhard Ralf ; Schmid, Franz X.:
Peptidyl-prolyl cis-trans isomerase improves the efficiency of protein disulfide isomerase as a catalyst of protein folding.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 89 (1992) Heft 10 . - S. 4510-4513.
ISSN 1091-6490

Kern, Gunther ; Schülke, Norbert ; Schmid, Franz X. ; Jaenicke, Rainer:
Stability, quaternary structure, and folding of internal, external, and core-glycosylated invertase from yeast.
In: Protein Science. Bd. 1 (1992) Heft 1 . - S. 120-131.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.5560010112

Kiefhaber, Thomas ; Schmid, Franz X. ; Willaert, Kathrien ; Engelborghs, Yves ; Chaffotte, Alain:
Structure of a rapidly formed intermediate in ribonuclease T1 folding.
In: Protein Science. Bd. 1 (1992) Heft 9 . - S. 1162-1172.
ISSN 1469-896X
DOI: https://doi.org/10.1002/pro.5560010910

1991

Schmid, Franz X.:
Catalysis and assistance of protein folding.
In: Current Opinion in Structural Biology. Bd. 1 (1991) Heft 1 . - S. 36-41.
ISSN 0959-440X
DOI: https://doi.org/10.1016/0959-440X(91)90008-H

Schönbrunner, Erhard Ralf ; Mayer, Sabine ; Tropschug, Maximilian ; Fischer, Gunter ; Takahashi, Nobuhiro ; Schmid, Franz X.:
Catalysis of protein folding by cyclophilins from different species.
In: The Journal of Biological Chemistry. Bd. 266 (1991) Heft 6 . - S. 3630-3635.
ISSN 1083-351X
DOI: https://doi.org/10.1016/S0021-9258(19)67841-5

Buchner, Johannes ; Schmidt, Marion ; Fuchs, Miriam ; Jaenicke, Rainer ; Rudolph, Rainer ; Schmid, Franz X. ; Kiefhaber, Thomas:
GroE facilitates refolding of citrate synthase by suppressing aggregation.
In: Biochemistry. Bd. 30 (1991) Heft 6 . - S. 1586-1591.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00220a020

Schmid, Franz X. ; Lang, Karl ; Kiefhaber, Thomas ; Mayer, Sabine ; Schönbrunner, Erhard Ralf:
Prolyl isomerase : role in protein folding and speculations on its function in the cell.
In: Nall, Barry T. ; Dill, K. A. (Hrsg.): Conformations and forces in Protein Folding. - Washington : AAAS Press , 1991 . - S. 198-203
ISBN 0-87168-394-6

1990

Kiefhaber, Thomas ; Quaas, Rainer ; Hahn, Ulrich ; Schmid, Franz X.:
Folding of ribonuclease T1. 1. Existence of multiple unfolded states created by proline isomerization.
In: Biochemistry. Bd. 29 (1990) Heft 12 . - S. 3053-3061.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00464a023

Kiefhaber, Thomas ; Quaas, Rainer ; Hahn, Ulrich ; Schmid, Franz X.:
Folding of ribonuclease T1. 2. Kinetic models for the folding and unfolding reactions.
In: Biochemistry. Bd. 29 (1990) Heft 12 . - S. 3061-3070.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00464a024

Tropschug, Maximilian ; Wachter, Elmar ; Mayer, Sabine ; Schönbrunner, Erhard Ralf ; Schmid, Franz X.:
Isolation and sequence of an FK506-binding protein from N. crassa which catalyses protein folding.
In: Nature. Bd. 346 (1990) Heft 6285 . - S. 674-677.
ISSN 1476-4687
DOI: https://doi.org/10.1038/346674a0

Kay, J. E. ; Moore, A. L. ; Doe, S. E. ; Benzie, C. R. ; Schönbrunner, Erhard Ralf ; Schmid, Franz X. ; Halestrap, A. P.:
The mechanism of action of FK 506.
In: Transplantation Proceedings. Bd. 22 (1990) Heft 1 . - S. 96-99.
ISSN 0041-1345

Fischer, Gunter ; Schmid, Franz X.:
The mechanism of protein folding : Implications of in vitro refolding models for de novo protein folding and translocation in the cell.
In: Biochemistry. Bd. 29 (1990) Heft 9 . - S. 2205-2212.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00461a001

Kiefhaber, Thomas ; Grunert, Hans Peter ; Hahn, Ulrich ; Schmid, Franz X.:
Replacement of a cis proline simplifies the mechanism of ribonuclease T1 folding.
In: Biochemistry. Bd. 29 (1990) Heft 27 . - S. 6475-6480.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00479a020

Lang, Kurt ; Schmid, Franz X.:
Role of two proline-containing turns in the folding of porcine ribonuclease.
In: Journal of Molecular Biology. Bd. 212 (1990) Heft 1 . - S. 185-196.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(90)90314-C

Kiefhaber, Thomas ; Schmid, Franz X. ; Renner, Michael ; Hinz, Hans J. ; Hahn, Ulrich ; Quaas, Rainer:
Stability of recombinant Lys25-ribonuclease T1.
In: Biochemistry. Bd. 29 (1990) Heft 36 . - S. 8250-8257.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00488a008

1989

Fischer, Gunter ; Wittmann-Liebold, Brigitte ; Lang, Kurt ; Kiefhaber, Thomas ; Schmid, Franz X.:
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins.
In: Nature. Bd. 337 (1989) Heft 6206 . - S. 476-478.
ISSN 1476-4687
DOI: https://doi.org/10.1038/337476a0

Schmid, Franz X.:
Spectral methods of characterizing protein conformation and conformational changes.
In: Creighton, Thomas E. (ed.): Protein Structure : a Practical Approach. - Oxford : IRL Press , 1989 . - S. 251-285 . - (The Practical Approach Series ; 45 )
ISBN 0-19-963001-1

1988

Schülke, Norbert ; Schmid, Franz X.:
Effect of glycosylation on the mechanism of renaturation of invertase from yeast.
In: The Journal of Biological Chemistry. Bd. 263 (1988) Heft 18 . - S. 8832-8837.
ISSN 1083-351X

Lang, Kurt ; Schmid, Franz X.:
Protein-disulphide isomerase and prolyl isomerase act differently and independently as catalysts of protein folding.
In: Nature. Bd. 331 (1988) Heft 6155 . - S. 453-455.
ISSN 1476-4687
DOI: https://doi.org/10.1038/331453a0

Schülke, Norbert ; Schmid, Franz X.:
The stability of yeast invertase is not significantly influenced by glycosylation.
In: The Journal of Biological Chemistry. Bd. 263 (1988) Heft 18 . - S. 8827-8831.
ISSN 1083-351X
DOI: https://doi.org/10.1016/S0021-9258(18)68381-4

1987

Lang, Kurt ; Schmid, Franz X. ; Fischer, Gunter:
Catalysis of protein folding by prolyl isomerase.
In: Nature. Bd. 329 (1987) Heft 6136 . - S. 268-270.
ISSN 1476-4687
DOI: https://doi.org/10.1038/329268a0

Grafl, Reinhard ; Lang, Kurt ; Vogl, H. ; Schmid, Franz X.:
The mechanism of folding of pancreatic ribonucleases is independent of the presence of covalently linked carbohydrate.
In: The Journal of Biological Chemistry. Bd. 262 (1987) Heft 22 . - S. 10624-10629.
ISSN 1083-351X
DOI: https://doi.org/10.1016/S0021-9258(18)61009-9

1986

Lang, Kurt ; Wrba, Alex ; Krebs, Herbert ; Schmid, Franz X. ; Beintema, Jaap J.:
Folding kinetics of mammalian ribonucleases.
In: FEBS Letters. Bd. 204 (1986) Heft 1 . - S. 135-9.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(86)81401-6

Grafl, Reinhard ; Lang, Kurt ; Wrba, Alex ; Schmid, Franz X.:
Folding mechanism of porcine ribonuclease.
In: Journal of Molecular Biology. Bd. 191 (1986) Heft 2 . - S. 281-293.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(86)90265-2

Schmid, Franz X.:
Proline isomerization during refolding of ribonuclease A is accelerated by the presence of folding intermediates.
In: FEBS Letters. Bd. 198 (1986) Heft 2 . - S. 217-220.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(86)80408-2

Schmid, Franz X. ; Grafl, Reinhard ; Wrba, Alex ; Beintema, Jaap J.:
Role of proline peptide bond isomerization in unfolding and refolding of ribonuclease.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 83 (1986) Heft 4 . - S. 872-876.
ISSN 1091-6490

Lang, Kurt ; Schmid, Franz X.:
Use of a trypsin-pulse method to study the refolding pathway of ribonuclease.
In: European Journal of Biochemistry. Bd. 159 (1986) Heft 2 . - S. 275-81.
ISSN 1432-1033
DOI: https://doi.org/10.1111/j.1432-1033.1986.tb09864.x

Schmid, Franz X.:
Fast-folding and slow-folding forms of unfolded proteins.
In: Hirs, Christophe H. W. (Hrsg.): Enzyme structure. Part L. - New York : Academic Press , 1986 . - S. 70-82 . - (Methods in Enzymology ; 131 )
ISBN 978-0-12-182031-2
DOI: https://doi.org/10.1016/0076-6879(86)31035-8

1985

Krebs, Herbert ; Schmid, Franz X. ; Jaenicke, Rainer:
Native-like folding intermediates of homologous ribonucleases.
In: Biochemistry. Bd. 24 (1985) Heft 15 . - S. 3846-3852.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00336a005

1984

Schmid, Franz X. ; Blaschek, Heidi:
An early intermediate in the folding of ribonuclease A is protected against cleavage by pepsin.
In: Biochemistry. Bd. 23 (1984) Heft 10 . - S. 2128-2133.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00305a004

Kuwajima, Kunihiro ; Schmid, Franz X.:
Experimental studies of folding kinetics and structural dynamics of small proteins.
In: Advances in Biophysics. Bd. 18 (1984) . - S. 43-74.
ISSN 1873-4618

Schmid, Franz X. ; Buonocore, Michael H. ; Baldwin, Robert L.:
Tests of the simple model of Lin and Brandts for the folding kinetics of ribonuclease A.
In: Biochemistry. Bd. 23 (1984) Heft 15 . - S. 3389-3394.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00310a002

1983

Krebs, Herbert ; Schmid, Franz X. ; Jaenicke, Rainer:
Folding of homologous proteinsm : The refolding of different ribonucleases is independent of sequence variations, proline content and glycosylation.
In: Journal of Molecular Biology. Bd. 169 (1983) Heft 2 . - S. 619-635.
ISSN 0022-2836
DOI: https://doi.org/10.1016/S0022-2836(83)80067-9

Schmid, Franz X.:
Mechanism of folding of ribonuclease A : Slow refolding is a sequential reaction via structural intermediates.
In: Biochemistry. Bd. 22 (1983) Heft 20 . - S. 4690-4696.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00289a013

1982

Schmid, Franz X.:
CD properties of the fast- and slow-folding forms of unfolded ribonuclease A.
In: FEBS Letters. Bd. 139 (1982) Heft 2 . - S. 190-192.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(82)80848-X

Rehage, Annette ; Schmid, Franz X.:
Fast- and slow-refolding forms of unfolded ribonuclease : A differ in tyrosine fluorescence.
In: Biochemistry. Bd. 21 (1982) Heft 7 . - S. 1499-1505.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00536a006

Schmid, Franz X.:
Proline isomerization in unfolded ribonuclease A : The equilibrium between fast-folding and slow-folding species is independent of temperature.
In: European Journal of Biochemistry. Bd. 128 (1982) Heft 1 . - S. 77-80.
ISSN 1432-1033
DOI: https://doi.org/10.1111/j.1432-1033.1982.tb06935.x

1981

Schmid, Franz X.:
A native-like intermediate on the ribonuclease A folding pathway 1 : Detection by tyrosine fluorescence changes.
In: European Journal of Biochemistry. Bd. 114 (1981) Heft 1 . - S. 105-109.
ISSN 1432-1033
DOI: https://doi.org/10.1111/j.1432-1033.1981.tb06179.x

Schmid, Franz X. ; Blaschek, Heidi:
A native-like intermediate on the ribonuclease A folding pathway 2 : Comparison of its properties to native ribonuclease A.
In: European Journal of Biochemistry. Bd. 114 (1981) Heft 1 . - S. 111-117.
ISSN 1432-1033

1979

Schmid, Franz X. ; Baldwin, Robert L.:
Detection of an early intermediate in the folding of ribonuclease A by protection of amide protons against exchange.
In: Journal of Molecular Biology. Bd. 135 (1979) Heft 1 . - S. 199-215.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(79)90347-4

Schmid, Franz X. ; Baldwin, Robert L.:
The rate of interconversion between the two unfolded forms of ribonuclease A does not depend on guanidinium chloride concentration.
In: Journal of Molecular Biology. Bd. 133 (1979) Heft 2 . - S. 285-287.
ISSN 0022-2836
DOI: https://doi.org/10.1016/0022-2836(79)90536-9

Hagerman, Paul J. ; Schmid, Franz X. ; Baldwin, Robert L.:
Refolding behavior of a kinetic intermediate observed in the low pH unfolding of ribonuclease A.
In: Biochemistry. Bd. 18 (1979) Heft 2 . - S. 293-297.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00569a009

Cook, Kem H. ; Schmid, Franz X. ; Baldwin, Robert L.:
Role of proline isomerization in folding of ribonuclease A at low temperatures.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 76 (1979) Heft 12 . - S. 6157-6161.
ISSN 1091-6490

Schmid, Franz X. ; Hinz, Hans J.:
Thermodynamic studies of the lactate dehydrogenase catalytic reaction.
In: Hoppe-Seyler's Zeitschrift für physiologische Chemie. Bd. 360 (1979) Heft 10 . - S. 1501-1504.
ISSN 0018-4888

1978

Schmid, Franz X. ; Baldwin, Robert L.:
Acid catalysis of the formation of the slow-folding species of RNase A : evidence that the reaction is proline isomerization.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 75 (1978) Heft 10 . - S. 4764-4768.
ISSN 1091-6490

Schmid, Franz X. ; Hinz, Hans J. ; Jaenicke, Rainer:
Studies on an energy structure-function relationship of dehydrogenases. I. Calorimetric investigations on the interaction of coenzyme fragments with horse liver alcohol dehydrogenase.
In: FEBS Letters. Bd. 87 (1978) Heft 1 . - S. 80-82.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(78)80138-0

Hinz, Hans J. ; Steininger, G. ; Schmid, Franz X. ; Jaenicke, Rainer:
Studies on an energy structure-function relationship of dehydrogenases. II. Calorimetric investigations on the interaction of coenzyme fragments with pig skeletal muscle lactate dehydrogenase.
In: FEBS Letters. Bd. 87 (1978) Heft 1 . - S. 83-86.
ISSN 1873-3468
DOI: https://doi.org/10.1016/0014-5793(78)80139-2

1976

Schmid, Franz X. ; Hinz, Hans J. ; Jaenicke, Rainer:
Detection of absorption changes of pig heart muscle lactate dehydrogenase in the wavelength range between 260 nm and 320 nm on ternary complex formation with NAD and oxalate.
In: Hoppe-Seyler's Zeitschrift für physiologische Chemie. Bd. 357 (1976) Heft 1 . - S. 241-245.
ISSN 0018-4888

Schmid, Franz X. ; Hinz, Hans J. ; Jaenicke, Rainer:
Thermodynamic studies of binary and ternary complexes of pig heart lactate dehydrogenase.
In: Biochemistry. Bd. 15 (1976) Heft 14 . - S. 3052-3059.
ISSN 1520-4995
DOI: https://doi.org/10.1021/bi00659a018