Institutionen der Universität Bayreuth
Lehrstuhl Biopolymere - Apl. Prof. Dr. Birgitta Wöhrl

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Anzahl der Einträge auf dieser Ebene: 165.

2023

Volltext
Hendrich, Julian ; Wangorsch, Andrea ; Rödel, Katharina ; Jacob, Thessa ; Mahler, Vera ; Wöhrl, Birgitta M.:
Allergenicity and IgE Recognition of New Dau c 1 Allergens from Carrot.
In: Molecular Nutrition & Food Research. Bd. 67 (2023) Heft 3 . - 2200421.
DOI: https://doi.org/10.1002/mnfr.202200421

Volltext
Zuber, Philipp:
Mechanistische Untersuchungen zur Regulation der bakteriellen Transkription durch NusG-Proteine.
Bayreuth , 2023 . - VI, 223 S.
( Dissertation, 2020 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00005246

Volltext
Adolph, Ramona S. ; Beck, Eileen ; Schweimer, Kristian ; Di Fonzo, Andrea ; Weyand, Michael ; Rösch, Paul ; Wöhrl, Birgitta M. ; Steegborn, Clemens:
Molecular Mechanism of Sirtuin 1 Inhibition by Human Immunodeficiency Virus 1 Tat Protein.
In: Life. Bd. 13 (2023) Heft 4 . - 949.
DOI: https://doi.org/10.3390/life13040949

2022

Zuber, Philipp ; Daviter, Tina ; Heißmann, Ramona ; Persau, Ulrike ; Schweimer, Kristian ; Knauer, Stefan H.:
Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins.
In: eLIFE. Bd. 11 (2022) . - e76630.
DOI: https://doi.org/10.7554/eLife.76630

2021

Volltext
Jacob, Thessa:
Biochemische und immunologische Charakterisierung der PR-10 Allergene Cor a 1 aus Hasel und Dau c 1 aus Karotte : Liganden, Stabilität, neue Isoallergene.
Bayreuth , 2021 . - I, 148 S.
( Dissertation, 2021 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00005423

Chruszcz, Maksymilian ; Chew, Fook Tim ; Hoffmann-Sommergruber, Karin ; Hurlburt, Barry K. ; Mueller, Geoffrey A. ; Pomés, Anna ; Rouvinen, Juha ; Villalba, Mayte ; Wöhrl, Birgitta M. ; Breiteneder, Heimo:
Allergens and their associated small molecule ligands : their dual role in sensitization.
In: Allergy European Journal Of Allergy And Clinical Immunology. Bd. 76 (2021) Heft 8 . - S. 2367-2382.
DOI: https://doi.org/10.1111/all.14861

Raynal, Betrand ; Brûlé, Sébastien ; Uebel, Stephan ; Knauer, Stefan H.:
Assessing and Improving Protein Sample Quality.
In: Daviter, Tina ; Johnson, Christopher M. ; McLaughlin, Stephen H. ; Williams, Mark A. (Hrsg.): Protein-Ligand Interactions : Methods and Applications. - New York : Springer, 2021 . - S. 3-46 . - (Methods in Molecular Biology ; 2263 )
DOI: https://doi.org/10.1007/978-1-0716-1197-5_1

Kröger, Pascal ; Shanmugaratnam, Sooruban ; Ferruz, Noelia ; Schweimer, Kristian ; Höcker, Birte:
A comprehensive binding study illustrates ligand recognition in the periplasmic binding protein PotF.
In: Structure. Bd. 29 (2021) Heft 5 . - S. 433-443.
DOI: https://doi.org/10.1016/j.str.2020.12.005

Volltext
Jacob, Thessa ; Wangorsch, Andrea ; Vogel, Lothar ; Reuter, Andreas ; Mahler, Vera ; Wöhrl, Birgitta M.:
A Novel Isoallergen Dau c 1.0401 in Carrot : Stability, Allergenicity, and Comparison with Other Isoallergens.
In: Molecular Nutrition & Food Research. Bd. 65 (2021) Heft 7 . - 2001110.
DOI: https://doi.org/10.1002/mnfr.202001110

Volltext
Boritzki, Vanessa ; Hübner, Harald ; Allikalt, Anni ; Gmeiner, Peter ; Wöhrl, Birgitta M.:
Optimizing the Expression of Human Dopamine Receptors in Escherichia coli.
In: International Journal of Molecular Sciences. Bd. 22 (2021) Heft 16 . - 8647.
DOI: https://doi.org/10.3390/ijms22168647

de Marco, Ario ; Berrow, Nick ; Lebendiker, Mario ; Garcia-Alai, Maria ; Knauer, Stefan H. ; Lopez-Mendez, Blanca ; Matagne, André ; Parret, Annabel ; Remans, Kim ; Uebel, Stephan ; Raynal, Bertrand:
Quality control of protein reagents for the improvement of research data reproducibility.
In: Nature Communications. Bd. 12 (2021) . - 2795.
DOI: https://doi.org/10.1038/s41467-021-23167-z

Berrow, Nick ; de Marco, Ario ; Lebendiker, Mario ; Garcia-Alai, Maria ; Knauer, Stefan H. ; Lopez-Mendetz, Blanca ; Matagne, André ; Parret, Annabel ; Remans, Kim ; Uebel, Stephan ; Raynal, Bertrand:
Quality control of purified proteins to improve data quality and reproducibility : results from a large-scale survey.
In: European Biophysics Journal with Biophysics Letters. Bd. 50 (2021) . - S. 453-460.
DOI: https://doi.org/10.1007/s00249-021-01528-2

López-Méndez, Blanca ; Baron, Bruno ; Brautigam, Chad A. ; Jowitt, Thomas A. ; Knauer, Stefan H. ; Uebel, Stephan ; Williams, Mark A. ; Sedivy, Arthur ; Abian, Olga ; Abreu, Celeste ; Adamczyk, Malgorzata ; Bal, Wojciech ; Berger, Sylvie ; Buell, Alexander K. ; Carolis, Carlo ; Daviter, Tina ; Fish, Alexander ; Garcia-Alai, Maria ; Guenther, Christian ; Hamacek, Josef ; Hoková, Jitka ; Houser, Josef ; Johnson, Chris ; Kelly, Sharon ; Leech, Andrew ; Mas, Caroline ; Matulis, Daumantas ; McLaughlin, Stephen H. ; Montserret, Roland ; Nasreddine, Rouba ; Nehmé, Reine ; Nguyen, Quyen ; Ortega-Alarcón, David ; Perez, Kathryn ; Pirc, Katja ; Piszczek, Grzegorz ; Podobnik, Marjetka ; Rodrigo, Natalia ; Rokov-Plavec, Jasmina ; Schäfer, Susanne ; Sharpe, Tim ; Southall, June ; Staunton, David ; Tavares, Pedro ; Vanek, Ondrej ; Weyand, Michael ; Wu, Di:
Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith : a multi laboratory benchmark study.
In: European Biophysics Journal with Biophysics Letters. Bd. 50 (2021) . - S. 411-427.
DOI: https://doi.org/10.1007/s00249-021-01532-6

Nowacka, Marzena ; Nowak, Elzbieta ; Czarnocki-Cieciura, Mariusz ; Jackiewicz, Justyna ; Skowronek, Krzysztof ; Szczepanowski, Roman H. ; Wöhrl, Birgitta M. ; Nowotny, Marcin:
Structures of substrate complexes of foamy viral protease-reverse transcriptase.
In: Journal of Virology. Bd. 95 (2021) Heft 18 . - e00848-21.
DOI: https://doi.org/10.1128/JVI.00848-21

2020

Liess, Anna K. L. ; Kucerova, Alena ; Schweimer, Kristian ; Schlesinger, Dörte ; Dybkov, Olexandr ; Urlaub, Henning ; Mansfeld, Jörg ; Lorenz, Sonja:
Dimerization regulates the human APC/C-associated ubiquitin-conjugating enzyme UBE2S.
In: Science Signaling. Bd. 13 (20 Oktober 2020) Heft 654 . - No. 8208.
DOI: https://doi.org/10.1126/scisignal.aba8208

Volltext
Boritzki, Vanessa:
Etablierung und Optimierung von in vivo- und in vitro-Systemen zur Erhöhung der Produktion sowie zur Stabilisierung der humanen Dopaminrezeptoren D2 und D3.
Bayreuth , 2020 . - V, 186 S.
( Dissertation, 2020 , Universität Bayreuth, Bayreuther Graduiertenschule für Mathematik und Naturwissenschaften - BayNAT)
DOI: https://doi.org/10.15495/EPub_UBT_00005145

Hartl, Frederike A. ; Beck-García, Esmeralda ; Woessner, Nadine M. ; Flachsmann, Lea J. ; Velasco Cárdenas, Rubí M.-H. ; Brandl, Simon M. ; Taromi, Sanaz ; Fiala, Gina J. ; Morath, Anna ; Mishra, Pankaj ; Yousefi, O. Sascha ; Zimmermann, Julia ; Hoefflin, Nico ; Köhn, Maja ; Wöhrl, Birgitta M. ; Zeiser, Robert ; Schweimer, Kristian ; Günther, Stefan ; Schamel, Wolfgang W. ; Minguet, Susana:
Noncanonical binding of Lck to CD3ε promotes TCR signaling and CAR function.
In: Nature Immunology. Bd. 21 (Juli 2020) . - S. 902-913.
DOI: https://doi.org/10.1038/s41590-020-0732-3

Galaz-Davison, Pablo ; Molina, José Alejandro ; Silletti, Steve ; Komives, Elizabeth A. ; Knauer, Stefan H. ; Artsimovitch, Irina ; Ramírez-Sarmiento, César A.:
Differential local stability governs the metamorphic fold-switch of bacterial virulence factor RfaH.
In: Biophysical Journal. Bd. 118 (2020) Heft 1 . - S. 96-104.
DOI: https://doi.org/10.1016/j.bpj.2019.11.014

Volltext
Washburn, Robert S. ; Zuber, Philipp ; Sun, Ming ; Hashem, Yaser ; Shen, Bingxin ; Li, Wen ; Harvey, Sho ; Reyes, Francisco J. Acosta ; Gottesman, Max E. ; Knauer, Stefan H. ; Frank, Joachim:
Escherichia coli NusG links the lead ribosome with the transcription elongation complex.
In: iScience. Bd. 23 (2020) Heft 8 . - 101352.
DOI: https://doi.org/10.1016/j.isci.2020.101352

Volltext
Jacob, Thessa ; Vogel, Lothar ; Reuter, Andreas ; Wangorsch, Andrea ; Kring, Carolin ; Mahler, Vera ; Wöhrl, Birgitta M.:
Food Processing does not Abolish the Allergenicity of the Carrot Allergen Dau c 1 : Influence of pH, Temperature and the Food Matrix.
In: Molecular Nutrition & Food Research. Bd. 64 (2020) Heft 18 . - 2000334.
DOI: https://doi.org/10.1002/mnfr.202000334

Volltext
Dudenhöffer, Benjamin R. ; Borggräfe, Jan ; Schweimer, Kristian ; Knauer, Stefan H.:
NusA directly interacts with antitermination factor Q from phage λ.
In: Scientific Reports. Bd. 10 (2020) . - 6607.
DOI: https://doi.org/10.1038/s41598-020-63523-5

2019

Liess, Anna K. L. ; Kucerova, Alena ; Schweimer, Kristian ; Yu, Lu ; Roumeliotis, Theodoros I. ; Diebold, Mathias ; Dybkov, Olexandr ; Sotriffer, Christoph ; Urlaub, Henning ; Choudhary, Jyoti S. ; Mansfeld, Jörg ; Lorenz, Sonja:
Autoinhibition Mechanism of the Ubiquitin-Conjugating Enzyme UBE2S by Autoubiquitination.
In: Structure. Bd. 27 (August 2019) Heft 8 . - S. 1195-1210.
DOI: https://doi.org/10.1016/j.str.2019.05.008

Artsimovitch, Irina ; Knauer, Stefan H.:
Ancient Transcription Factors in the News.
In: mBio. Bd. 10 (2019) Heft 1 . - e01547-18.
DOI: https://doi.org/10.1128/mBio.01547-18

Brinson, Robert G. ; Marino, John P. ; Delaglio, Frank ; Arbogast, Luke W. ; Evans, Ryan M. ; Kearsley, Anthony ; Gingras, Geneviève ; Ghasriani, Houman ; Aubin, Yves ; Pierens, Gregory K. ; Jia, Xinying ; Mobli, Mehdi ; Grant, Hamish G. ; Keizer, David W. ; Schweimer, Kristian ; Ståhle, Jonas ; Widmalm, Göran ; Zartler, Edward R. ; Lawrence, Chad W. ; Reardon, Patrick N. ; Cort, John R. ; Xu, Ping ; Ni, Feng ; Yanaka, Saeko ; Kato, Koichi ; Parnham, Stuart R. ; Tsao, Desiree ; Blomgren, Andreas ; Rundlöf, Torgny ; Trieloff, Nils ; Schmieder, Peter ; Ross, Alfred ; Skidmore, Ken ; Chen, Kang ; Keire, David ; Freedberg, Darón I. ; Suter-Stahel, Thea ; Wider, Gerhard ; Ilc, Gregor ; Plavec, Janez ; Bradley, Scott A. ; Baldisseri, Donna M. ; Sforça, Mauricio Luis ; Zeri, Ana Carolina de Mattos ; Wei, Julie Yu ; Szabo, Christina M. ; Amezcua, Carlos A. ; Jordan, John B. ; Wikström, Mats:
Enabling adoption of 2D-NMR for the higher order structure assessment of monoclonal antibody therapeutics.
In: mAbs. Bd. 11 (2019) Heft 1 . - S. 94-105.
DOI: https://doi.org/10.1080/19420862.2018.1544454

Volltext
Jacob, Thessa ; Seutter von Loetzen, Christian ; Reuter, Andreas ; Lacher, Ulrike ; Schiller, Dirk ; Schobert, Rainer ; Mahler, Vera ; Vieths, Stefan ; Rösch, Paul ; Schweimer, Kristian ; Wöhrl, Birgitta M.:
Identification of a natural ligand of the hazel allergen Cor a 1.
In: Scientific Reports. Bd. 9 (2019) . - 8714.
DOI: https://doi.org/10.1038/s41598-019-44999-2

Zuber, Philipp ; Schweimer, Kristian ; Rösch, Paul ; Artsimovitch, Irina ; Knauer, Stefan H.:
Reversible fold-switching controls the functional cycle of the antitermination factor RfaH.
In: Nature Communications. Bd. 10 (2019) . - 702.
DOI: https://doi.org/10.1038/s41467-019-08567-6

Volltext

Volltext
Dudenhöffer, Benjamin R. ; Schneider, Hans ; Schweimer, Kristian ; Knauer, Stefan H.:
SuhB is an integral part of the ribosomal antitermination complex and interacts with NusA.
In: Nucleic Acids Research. Bd. 47 (2019) Heft 12 . - S. 6504-6518.
DOI: https://doi.org/10.1093/nar/gkz442

2018

Zuber, Philipp ; Hahn, Lukas ; Reinl, Anne ; Schweimer, Kristian ; Knauer, Stefan H. ; Gottesman, Max E. ; Rösch, Paul ; Wöhrl, Birgitta M.:
Structure and nucleic acid binding properties of KOW domains 4 and 6–7 of human transcription elongation factor DSIF.
In: Scientific Reports. Bd. 8 (2018) . - 11660.
DOI: https://doi.org/10.1038/s41598-018-30042-3

Zuber, Philipp ; Artsimovitch, Irina ; NandyMazumdar, Monali ; Liu, Zhaokun ; Nedialkov, Yuri ; Schweimer, Kristian ; Rösch, Paul ; Knauer, Stefan H.:
The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand.
In: eLIFE. Bd. 7 (2018) . - e36349.
DOI: https://doi.org/10.7554/eLife.36349

2017

Drögemüller, Johanna ; Schneider, Christin ; Schweimer, Kristian ; Strauß, Martin ; Wöhrl, Birgitta M. ; Rösch, Paul ; Knauer, Stefan H.:
Thermotoga maritima NusG : domain interaction mediates autoinhibition and thermostability.
In: Nucleic Acids Research. Bd. 45 (2017) Heft 1 . - S. 446-460.
DOI: https://doi.org/10.1093/nar/gkw1111

2016

Volltext
Schneider, Anna ; Corona, Angela ; Spöring, Imke ; Jordan, Mareike ; Buchholz, Bernd ; Maccioni, Elias ; di Santo, Roberto ; Bodem, Jochen ; Tramontano, Enzo ; Wöhrl, Birgitta M.:
Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase : antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
In: Nucleic Acids Research. (4 Februar 2016) Heft 1 . - 13 S..
DOI: https://doi.org/10.1093/nar/gkw060

Bauer, Joschka ; Schaal, Daniel ; Eisoldt, Lukas ; Schweimer, Kristian ; Schwarzinger, Stephan ; Scheibel, Thomas:
Acidic Residues Control the Dimerization of the N-terminal Domain of Black Widow Spiders' Major Ampullate Spidroin 1.
In: Scientific Reports. Bd. 6 (2016) . - 34442.
DOI: https://doi.org/10.1038/srep34442

Schaal, Daniel ; Bauer, Joschka ; Schweimer, Kristian ; Scheibel, Thomas ; Rösch, Paul ; Schwarzinger, Stephan:
Resonance assignment of an engineered amino-terminal domain of a major ampullate spider silk with neutralized charge cluster.
In: Biomolecular NMR Assignments. Bd. 10 (2016) . - S. 199-202.
DOI: https://doi.org/10.1007/s12104-016-9666-y

Strauß, Martin ; Vitiello, Christal ; Schweimer, Kristian ; Gottesman, Max E. ; Rösch, Paul ; Knauer, Stefan H.:
Transcription is regulated by NusA:NusG interaction.
In: Nucleic Acids Research. Bd. 44 (2016) Heft 12 . - S. 5971-5982.
DOI: https://doi.org/10.1093/nar/gkw423

Volltext
Strauß, Martin ; Schweimer, Kristian ; Burmann, Björn M. ; Richter, Anne ; Güttler, Stephanie ; Wöhrl, Birgitta M. ; Rösch, Paul:
The two domains of Mycobacterium tuberculosis NusG protein are dynamically independent.
In: Journal of Biomolecular Structure & Dynamics. Bd. 34 (2016) Heft 2 . - S. 352-361.
DOI: https://doi.org/10.1080/07391102.2015.1031700

2015

Volltext
Schneider, Anna ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
AZT resistance alters enzymatic properties and creates an ATP-binding site in SFVmac reverse transcriptase.
In: Retrovirology. Bd. 12 (2015) . - 21.
DOI: https://doi.org/10.1186/s12977-015-0147-7

Drögemüller, Johanna ; Strauß, Martin ; Schweimer, Kristian ; Jurk, Marcel ; Rösch, Paul ; Knauer, Stefan H.:
Determination of RNA polymerase binding surfaces of transcription factors by NMR spectroscopy.
In: Scientific Reports. Bd. 5 (2015) . - 16428.
DOI: https://doi.org/10.1038/srep16428

Volltext
Drögemüller, Johanna ; Strauß, Martin ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Knauer, Stefan H. ; Rösch, Paul:
Exploring RNA polymerase regulation by NMR spectroscopy.
In: Scientific Reports. Bd. 5 (2015) . - 10825.
DOI: https://doi.org/10.1038/srep10825

Husslik, Felix ; Hanschmann, Kay-Martin ; Krämer, Ariane ; Seutter von Loetzen, Christian ; Schweimer, Kristian ; Bellinghausen, Iris ; Treudler, Regina ; Simon, Jan C. ; Vogel, Lothar ; Völker, Elke ; Randow, Stefanie ; Reuter, Andreas ; Rösch, Paul ; Vieths, Stefan ; Holzhauser, Thomas ; Schiller, Dirk:
Folded or Not? Tracking Bet v 1 Conformation in Recombinant Allergen Preparations.
In: PLoS One. Bd. 10 (2015) Heft 7 . - e0132956.
DOI: https://doi.org/10.1371/journal.pone.0132956

Volltext
Seutter von Loetzen, Christian ; Jacob, Thessa ; Hartl-Spiegelhauer, Olivia ; Vogel, Lothar ; Schiller, Dirk ; Spörlein-Güttler, Cornelia ; Schobert, Rainer ; Vieths, Stefan ; Hartl, Maximilian J. ; Rösch, Paul:
Ligand Recognition of the Major Birch Pollen Allergen Bet v 1 is Isoform Dependent.
In: PLoS One. Bd. 10 (2015) Heft 6 . - e0128677.
DOI: https://doi.org/10.1371/journal.pone.0128677

2014

Volltext
Corona, Angela ; Schneider, Anna ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M. ; Tramontano, Enzo:
Inhibition of foamy virus reverse transcriptase by human immunodeficiency virus type 1 ribonuclease H inhibitors.
In: Antimicrobial Agents and Chemotherapy. Bd. 58 (2014) Heft 7 . - S. 4086-4093.
DOI: https://doi.org/10.1128/AAC.00056-14

Weiglmeier, Philipp Richard ; Berkner, Hanna ; Seebahn, Angela ; Vogel, Nico ; Schreiber, Rainer ; Wöhrl, Birgitta M. ; Schwarzinger, Stephan ; Rösch, Paul:
Prosequence switching : An effective strategy to produce biologically active E. coli heat-stable enterotoxin STh.
In: Journal of Biomolecular Structure & Dynamics. Bd. 32 (2014) Heft 10 . - S. 1-9.
DOI: https://doi.org/10.1080/07391102.2013.825758

Seutter von Loetzen, Christian ; Hoffmann, Thomas ; Hartl, Maximilian J. ; Schweimer, Kristian ; Schwab, Wilfried ; Rösch, Paul ; Hartl-Spiegelhauer, Olivia:
Secret of the major birch pollen allergen Bet v 1 : identification of the physiological ligand.
In: Biochemical Journal. Bd. 457 (2014) Heft 3 . - S. 379-390.
DOI: https://doi.org/10.1042/BJ20130413

Volltext
Schneider, Anna ; Peter, Daniel ; Schmitt, Jessica ; Leo, Berit ; Richter, Franziska ; Rösch, Paul ; Wöhrl, Birgitta M. ; Hartl, Maximilian J.:
Structural requirements for enzymatic activities of foamy virus protease-reverse transcriptase.
In: Proteins. Bd. 82 (2014) Heft 3 . - S. 375-385.
DOI: https://doi.org/10.1002/prot.24394

2013

Volltext
Drögemüller, Johanna ; Stegmann, Christian M. ; Mandal, Angshuman ; Steiner, Thomas ; Burmann, Björn M. ; Gottesman, Max E. ; Wöhrl, Birgitta M. ; Rösch, Paul ; Wahl, Markus C. ; Schweimer, Kristian:
An Autoinhibited State in the Structure of Thermotoga maritima NusG.
In: Structure. Bd. 21 (2013) Heft 3 . - S. 365-375.
DOI: https://doi.org/10.1016/j.str.2012.12.015

Volltext
Spannaus, Ralf ; Schneider, Anna ; Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Bodem, Jochen:
Foamy Virus Gag p71-p68 Cleavage Is Required for Template Switch of the Reverse Transcriptase.
In: Journal of Virology. Bd. 87 (2013) Heft 13 . - S. 7774-7776.
DOI: https://doi.org/10.1128/JVI.00833-13

Tomar, Sushil Kumar ; Knauer, Stefan H. ; NandyMazumdar, Monali ; Rösch, Paul ; Artsimovitch, Irina:
Interdomain contacts control folding of transcription factor RfaH.
In: Nucleic Acids Research. Bd. 41 (2013) Heft 22 . - S. 10077-10085.
DOI: https://doi.org/10.1093/nar/gkt779

Knauer, Stefan H. ; Rösch, Paul ; Artsimovitch, Irina:
Transformers : the science, not the fiction.
In: Protein Data Bank in Europe.
2013

Volltext
Schrom, Eva-Maria ; Moschall, Rebecca ; Hartl, Maximilian J. ; Weitner, Helena ; Fecher, David ; Langemeier, Jörg ; Bohne, Jens ; Wöhrl, Birgitta M. ; Bodem, Jochen:
U1snRNP-mediated suppression of polyadenylation in conjunction with the RNA structure controls poly (A) site selection in foamy viruses.
In: Retrovirology. Bd. 10 (2013) Heft 1 . - S. 55.
DOI: https://doi.org/10.1186/1742-4690-10-55

2012

Camilloni, Carlo ; Schaal, Daniel ; Schweimer, Kristian ; Schwarzinger, Stephan ; de Simone, Alfonso:
Energy landscape of the prion protein helix 1 probed by metadynamics and NMR.
In: Biophysical Journal. Bd. 102 (2012) Heft 1 . - S. 158-167.
DOI: https://doi.org/10.1016/j.bpj.2011.12.003

Hartl, Maximilian J. ; Burmann, Björn M. ; Prasch, Stefan J. ; Schwarzinger, Clemens ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Rösch, Paul ; Schwarzinger, Stephan:
Fast Mapping of Biomolecular Interfaces by Random Spin Labeling (RSL).
In: Journal of Biomolecular Structure & Dynamics. Bd. 29 (2012) Heft 4 . - S. 793-798.

Knauer, Stefan H. ; Hartl-Spiegelhauer, Olivia ; Schwarzinger, Stephan ; Hänzelmann, Petra ; Dobbek, Holger:
The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers.
In: The FEBS Journal. Bd. 279 (2012) Heft 5 . - S. 816-831.
DOI: https://doi.org/10.1111/j.1742-4658.2012.08473.x

Volltext
Burmann, Björn M. ; Knauer, Stefan H. ; Sevostyanova, Anastasia ; Schweimer, Kristian ; Mooney, Rachel A. ; Landick, Robert ; Artsimovitch, Irina ; Rösch, Paul:
An α helix to β barrel domain switch transforms the transcription factor RfaH into a translation factor.
In: Cell. Bd. 150 (2012) Heft 2 . - S. 291-303.
DOI: https://doi.org/10.1016/j.cell.2012.05.042

Volltext
Härteis, Silke ; Schaal, Daniel ; Brauer, Felix ; Brüschke, Stefan ; Schweimer, Kristian ; Rauh, Robert ; Sticht, Heinrich ; Rösch, Paul ; Schwarzinger, Stephan ; Korbmacher, Christoph:
An inhibitory peptide derived from the alpha-subunit of the epithelial sodium channel (ENaC) shows a helical conformation.
In: Cellular Physiology and Biochemistry. Bd. 29 (2012) . - S. 761-774.
DOI: https://doi.org/10.1159/000312590

Volltext
Leo, Berit ; Hartl, Maximilian J. ; Schweimer, Kristian ; Mayr, Florian ; Wöhrl, Birgitta M.:
Insights into the structure and activity of prototype foamy virus RNase H.
In: Retrovirology. Bd. 9 (2012) Heft 1 .
DOI: https://doi.org/10.1186/1742-4690-9-14

Knauer, Stefan H. ; Buckel, Wolfgang ; Dobbek, Holger:
On the ATP-dependent activation of the radical enzyme (R)-2-hydroxyisocaproyl-CoA dehydratase.
In: Biochemistry. Bd. 51 (2012) Heft 33 . - S. 6609-6622.
DOI: https://doi.org/10.1021/bi300571z

Volltext
Spannaus, Ralf ; Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Rethwilm, Axel ; Bodem, Jochen:
The prototype foamy virus protease is active independently of the integrase domain.
In: Retrovirology. Bd. 9 (2012) Heft 1 .
DOI: https://doi.org/10.1186/1742-4690-9-41

Leo, Berit ; Schweimer, Kristian ; Rösch, Paul ; Hartl, Maximilian J. ; Wöhrl, Birgitta M.:
The solution structure of the prototype foamy virus RNase H domain indicates an important role of the basic loop in substrate binding.
In: Retrovirology. Bd. 9 (2012) . - 73.
DOI: https://doi.org/10.1186/1742-4690-9-73

Seutter von Loetzen, Christian ; Schweimer, Kristian ; Schwab, Wilfried ; Rösch, Paul ; Hartl-Spiegelhauer, Olivia:
Solution structure of the strawberry allergen Fra a 1.
In: Bioscience Reports. Bd. 32 (2012) Heft 6 . - S. 567-575.
DOI: https://doi.org/10.1042/BSR20120058

Volltext
Knauer, Stefan H. ; Rösch, Paul ; Artsimovitch, Irina:
Transformation : The next level of regulation.
In: RNA Biology. Bd. 9 (2012) Heft 12 . - S. 1418-1423.
DOI: https://doi.org/10.4161/rna.22724

Knauer, Stefan H. ; Artsimovitch, Irina ; Rösch, Paul:
Transformer proteins.
In: Cell Cycle. Bd. 11 (2012) Heft 23 . - S. 4289-4290.
DOI: https://doi.org/10.4161/cc.22468

2011

Volltext
Unal, Can ; Schwedhelm, Kai F. ; Thiele, Alexandra ; Weiwad, Matthias ; Schweimer, Kristian ; Frese, Frederike ; Fischer, Gunter ; Hacker, Jörg ; Faber, Cornelius ; Steinert, Michael:
Collagen IV-derived peptide binds hydrophobic cavity of Legionella pneumophila Mip and interferes with bacterial epithelial transmigration.
In: Cellular Microbiology. Bd. 13 (2011) Heft 10 . - S. 1558-1572.
DOI: https://doi.org/10.1111/j.1462-5822.2011.01641.x

Burmann, Björn M. ; Scheckenhofer, Ulrich ; Schweimer, Kristian ; Rösch, Paul:
Domain interactions of the transcription-translation coupling factor Escherichia coli NusG are intermolecular and transient.
In: Biochemical Journal. Bd. 435 (2011) Heft 3 . - S. 783-789.
DOI: https://doi.org/10.1042/BJ20101679

Volltext
Schweimer, Kristian ; Prasch, Stefan J. ; Sujatha, Pagadala Santhanam ; Bubunenko, Mikhail ; Gottesman, Max E. ; Rösch, Paul:
NusA Interaction with the α Subunit of E. coli RNA Polymerase Is via the UP Element Site and Releases Autoinhibition.
In: Structure. Bd. 19 (2011) Heft 7 . - S. 945-954.
DOI: https://doi.org/10.1016/j.str.2011.03.024

Volltext
Juli, Christina ; Sippel, Martin ; Jäger, Jens ; Thiele, Alexandra ; Weiwad, Matthias ; Schweimer, Kristian ; Rösch, Paul ; Steinert, Michael ; Sotriffer, Christoph ; Holzgrabe, Ulrike:
Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein.
In: Journal of Medicinal Chemistry. Bd. 54 (2011) Heft 1 . - S. 277-283.
DOI: https://doi.org/10.1021/jm101156y

Polzien, Lisa ; Baljuls, Angela ; Roth, Heide-Marie ; Kuper, Jochen ; Benz, Roland ; Schweimer, Kristian ; Hekman, Mirko ; Rapp, Ulf R.:
Pore-forming activity of BAD is regulated by specific phosphorylation and structural transitions of the C-terminal part.
In: Biochimica et Biophysica Acta : General Subjects. Bd. 1810 (2011) Heft 2 . - S. 162-169.
DOI: https://doi.org/10.1016/j.bbagen.2010.11.002

Volltext
Hartl, Maximilian J. ; Bodem, Jochen ; Jochheim, Fabian ; Rethwilm, Axel ; Rösch, Paul ; Wöhrl, Birgitta M.:
Regulation of foamy virus protease activity by viral RNA.
In: Journal of Virology. Bd. 85 (2011) Heft 9 . - S. 4462-4469.
DOI: https://doi.org/10.1128/JVI.02211-10

Knauer, Stefan H. ; Buckel, Wolfgang ; Dobbek, Holger:
Structural Basis for Reductive Radical Formation and Electron Recycling in (R)-2-Hydroxyisocaproyl-CoA Dehydratase.
In: Journal of the American Chemical Society. Bd. 133 (2011) Heft 12 . - S. 4342-4347.
DOI: https://doi.org/10.1021/ja1076537

2010

Volltext
Hartl, Maximilian J. ; Mayr, Florian ; Rethwilm, Axel ; Wöhrl, Birgitta M.:
Biophysical and enzymatic properties of the simian and prototype foamy virus reverse transcriptases.
In: Retrovirology. Bd. 7 (29 Januar 2010) Heft 1 . - 10 S.
DOI: https://doi.org/10.1186/1742-4690-7-5

Wenzel, Sabine ; Martins, Berta M. ; Rösch, Paul ; Wöhrl, Birgitta M.:
Crystal structure of the human transcription elongation factor DSIF hSpt4 subunit in complex with the hSpt5 dimerization interface.
In: Biochemical Journal. Bd. 425 (2010) Heft 2 . - S. 373-380.
DOI: https://doi.org/10.1042/BJ20091422

Spiegelhauer, Olivia ; Mende, Sophia ; Dickert, Frank ; Knauer, Stefan H. ; Ullmann, G. Matthias ; Dobbek, Holger:
Cysteine as a modulator residue in the active site of xenobiotic reductase A : a structural, thermodynamic and kinetic study.
In: Journal of Molecular Biology. Bd. 398 (2010) Heft 1 . - S. 66-82.
DOI: https://doi.org/10.1016/j.jmb.2010.02.044

Spiegelhauer, Olivia ; Werther, T. ; Mende, Sophia ; Knauer, Stefan H. ; Dobbek, Holger:
Determinants of Substrate Binding and Protonation in the Flavoenzyme Xenobiotic Reductase A.
In: Journal of Molecular Biology. Bd. 403 (2010) Heft 2 . - S. 286-298.
DOI: https://doi.org/10.1016/j.jmb.2010.08.047

Hartl, Maximilian J. ; Schweimer, Kristian ; Reger, Martin ; Schwarzinger, Stephan ; Bodem, Jochen ; Rösch, Paul ; Wöhrl, Birgitta M.:
Formation of transient dimers by a retroviral protease.
In: Biochemical Journal. Bd. 427 (2010) Heft 2 . - S. 197-203.
DOI: https://doi.org/10.1042/BJ20091451

Burmann, Björn M. ; Schweimer, Kristian ; Luo, Xiao ; Wahl, Markus C. ; Stitt, Barbara L. ; Gottesman, Max E. ; Rösch, Paul:
A NusE:NusG complex links transcription and translation.
In: Science. Bd. 328 (2010) Heft 5977 . - S. 501-504.
DOI: https://doi.org/10.1126/science.1184953

2009

Mangels, Christian ; Frank, Andreas ; Ziegler, Jan ; Klingenstein, R. ; Schweimer, Kristian ; Willbold, Dieter ; Korth, Carsten ; Rösch, Paul ; Schwarzinger, Stephan:
Binding of TCA to the Prion Protein : Mechanism, Implication for Therapy, and Application as Probe for Complex Formation of Bio-macromolecules.
In: Journal of Biomolecular Structure & Dynamics. Bd. 27 (2009) Heft 2 . - S. 163-170.
DOI: https://doi.org/10.1080/07391102.2009.10507306

Berkner, Hanna ; Neudecker, Philipp ; Mittag, Diana ; Ballmer-Weber, Barbara K. ; Schweimer, Kristian ; Vieths, Stefan ; Rösch, Paul:
Cross-reactivity of pollen and food allergens : soybean Gly m 4 is a member of the Bet v 1 superfamily and closely resembles yellow lupine proteins.
In: Bioscience Reports. Bd. 29 (2009) Heft 3 . - S. 183-192.
DOI: https://doi.org/10.1042/BSR20080117

Knake, Claudia ; Burmann, Björn M. ; Schweimer, Kristian ; Matecko, Irena ; Rösch, Paul:
The Membrane Proximal Extracellular Domain of Human hGC-B Folds Independently.
In: Journal of Biomolecular Structure & Dynamics. Bd. 26 (2009) Heft 4 . - S. 465-72.
DOI: https://doi.org/10.1080/07391102.2009.10507261

Weininger, Ulrich ; Haupt, Caroline ; Schweimer, Kristian ; Graubner, Wenke ; Kovermann, Michael ; Brüser, Thomas ; Scholz, Christian ; Schaarschmidt, Peter ; Zoldák, Gabriel ; Schmid, Franz X. ; Balbach, Jochen:
NMR solution structure of SlyD from Escherichia coli : spatial separation of prolyl isomerase and chaperone function.
In: Journal of Molecular Biology. Bd. 387 (2009) Heft 2 . - S. 295-305.
DOI: https://doi.org/10.1016/j.jmb.2009.01.034

Volltext
Weininger, Ulrich ; Jakob, Roman P. ; Eckert, Barbara ; Schweimer, Kristian ; Schmid, Franz X. ; Balbach, Jochen:
A remote prolyl isomerization controls domain assembly via a hydrogen bonding network.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 106 (2009) Heft 30 . - 12335 -12340.
DOI: https://doi.org/10.1073/pnas.0902102106

Prasch, Stefan J. ; Jurk, Marcel ; Washburn, Robert S. ; Gottesman, Max E. ; Wöhrl, Birgitta M. ; Rösch, Paul:
RNA-binding specificity of E. coli NusA.
In: Nucleic Acids Research. Bd. 37 (2009) Heft 14 . - S. 4736-4742.
DOI: https://doi.org/10.1093/nar/gkp452

Volltext
Kellner, Ruth ; Mangels, Christian ; Schweimer, Kristian ; Prasch, Stefan J. ; Weiglmeier, Philipp Richard ; Rösch, Paul ; Schwarzinger, Stephan:
SEMPRE: Spectral Editing Mediated by Paramagnetic Relaxation Enhancement.
In: Journal of the American Chemical Society. Bd. 131 (2009) Heft 50 . - S. 18016-18017.
DOI: https://doi.org/10.1021/ja905412z

Volltext
Mooney, Rachel A. ; Schweimer, Kristian ; Rösch, Paul ; Gottesman, Max E. ; Landick, Robert:
Two Structurally Independent Domains of E. coli NusG Create Regulatory Plasticity via Distinct Interactions with RNA Polymerase and Regulators.
In: Journal of Molecular Biology. Bd. 391 (2009) Heft 2 . - S. 341-358.
DOI: https://doi.org/10.1016/j.jmb.2009.05.078

2008

Hartl, Maximilian J. ; Kretzschmar, Benedikt ; Frohn, Anne ; Nowrouzi, Ali ; Rethwilm, Axel ; Wöhrl, Birgitta M.:
AZT resistance of simian foamy virus reserve transcriptase is based on the excision of AZTMP in the presence of ATP.
In: Nucleic Acids Research. Bd. 36 (Februar 2008) Heft 3 . - S. 1009-1016.
DOI: https://doi.org/10.1093/nar/gkm1087 PMCID: PMC2241919

Kretzschmar, Benedikt ; Nowrouzi, Ali ; Hartl, Maximilian J. ; Gärtner, Kathleen ; Wiktorowicz, Tatiana ; Herchenröder, Ottmar ; Kanzler, Sylvia ; Rudolph, Wolfram ; Mergia, Ayalew ; Wöhrl, Birgitta M. ; Rethwilm, Axel:
AZT-resistant foamy virus.
In: Virology. Bd. 370 (Januar 2008) Heft 1 . - S. 151-157.
DOI: https://doi.org/10.1016/j.virol.2007.08.025

Berkner, Hanna ; Schweimer, Kristian ; Matecko, Irena ; Rösch, Paul:
Conformation, catalytic site, and enzymatic mechanism of the PR10 allergen-related enzyme norcoclaurine synthase.
In: Biochemical Journal. Bd. 413 (2008) Heft 2 . - S. 281-290.
DOI: https://doi.org/10.1042/BJ20080306

Rao Jampani, Nageswara ; Schweimer, Kristian ; Wenzel, Sabine ; Wöhrl, Birgitta M. ; Rösch, Paul:
NELF-E RRM undergoes major structural changes in flexible protein regions on target RNA binding.
In: Biochemistry. Bd. 47 (2008) Heft 12 . - S. 3756-3761.
DOI: https://doi.org/10.1021/bi702429m

Wenzel, Sabine ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
The small hSpt4 subunit of the human transcription elongation factor DSIF is a Zn-finger protein with α/β type topology.
In: Biochemical and Biophysical Research Communications. Bd. 370 (2008) Heft 3 . - S. 414-418.
DOI: https://doi.org/10.1016/j.bbrc.2008.03.080

Schweimer, Kristian ; Petersen, Arnd ; Suck, Roland ; Becker, Wolf-Meinhard ; Rösch, Paul ; Matecko, Irena:
Solution structure of Phl p 3, a major allergen from timothy grass pollen.
In: Biological Chemistry. Bd. 389 (2008) Heft 7 . - S. 919-923.
DOI: https://doi.org/10.1515/BC.2008.102

Ceymann, Andreas ; Horstmann, Martin ; Ehses, Philipp ; Schweimer, Kristian ; Paschke, Anne-Katrin ; Steinert, Michael ; Faber, Cornelius:
Solution structure of the Legionella pneumophila Mip-rapamycin complex.
In: BMC Structural Biology. Bd. 8 (2008) . - 17.
DOI: https://doi.org/10.1186/1472-6807-8-17

Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Rösch, Paul ; Schweimer, Kristian:
The Solution Structure of the Simian Foamy Virus Protease Reveals a Monomeric Protein.
In: Journal of Molecular Biology. Bd. 381 (2008) Heft 1 . - S. 141-149.
DOI: https://doi.org/10.1016/j.jmb.2008.05.064

Matecko, Irena ; Burmann, Björn M. ; Schweimer, Kristian ; Kalbacher, Hubert ; Einsiedel, Jürgen ; Gmeiner, Peter ; Rösch, Paul:
Structural characterisation of the E.coli heat stable enterotoxin STh.
In: The Open Spectroscopy Journal. Bd. 2 (2008) . - S. 34-39.
DOI: https://doi.org/10.2174/1874383800802010034

Löw, Christian ; Weininger, Ulrich ; Lee, Hwankyu ; Schweimer, Kristian ; Neundorf, Ines ; Beck-Sickinger, Annette G. ; Pastor, Richard W. ; Balbach, Jochen:
Structure and dynamics of Helix-0 of the N-BAR domain in Lipid Micelles and Bilayers.
In: Biophysical Journal. Bd. 95 (2008) Heft 9 . - S. 4315-4323.
DOI: https://doi.org/10.1529/biophysj.108.134155

Schmalz, Holger ; Schmelz, Joachim ; Drechsler, Markus ; Yuan, Jiayin ; Walther, Andreas ; Schweimer, Kristian ; Mihut, Adriana M.:
Thermo-reversible formation of wormlike micelles with a microphase-separated corona from a semicrystalline triblock terpolymer.
In: Macromolecules. Bd. 41 (2008) Heft 9 . - S. 3235-3242.
DOI: https://doi.org/10.1021/ma702417y

Burmann, Björn M. ; Uc-Mass, Augusto ; Schweimer, Kristian ; Gottesman, Max E. ; Rösch, Paul:
The Y39A mutation of HK022 Nun disrupts a boxB interaction but preserves termination activity.
In: Biochemistry. Bd. 47 (2008) Heft 28 . - S. 7335-7341.
DOI: https://doi.org/10.1021/bi8004347

2007

Berkner, Hanna ; Engelhorn, Julia ; Liscombe, David K. ; Schweimer, Kristian ; Wöhrl, Birgitta M. ; Facchini, Peter J. ; Rösch, Paul ; Matecko, Irena:
High-yield expression and purification of isotopically labeled norcoclaurine synthase, a Bet v 1-homologous enzyme, from Thalictrum flavum for NMR studies.
In: Protein Expression and Purification. Bd. 56 (2007) Heft 2 . - S. 197-204.
DOI: https://doi.org/10.1016/j.pep.2007.07.010

Hartl, Maximilian J. ; Wöhrl, Birgitta M. ; Schweimer, Kristian:
Sequence-specific ¹H, ¹³C and ¹⁵N resonance assignments and secondary structure of a truncated protease from Simian Foamy Virus.
In: Biomolecular NMR Assignments. Bd. 1 (2007) . - S. 175-177.
DOI: https://doi.org/10.1007/s12104-007-9048-6

Bollig, Klaus ; Lamshöft, Marc ; Schweimer, Kristian ; Marner, Franz-Josef ; Budzikiewicz, Herbert ; Waffenschmidt, Sabine:
Structural analysis of linear hydroxyproline-bound O-glycans of Chlamydomonas reinhardtii : conservation of the inner core in Chlamydomonas and land plants.
In: Carbohydrate Research. Bd. 342 (2007) Heft 17 . - S. 2557-2566.
DOI: https://doi.org/10.1016/j.carres.2007.08.008

2006

Horstmann, Martin ; Ehses, Philipp ; Schweimer, Kristian ; Steinert, Michael ; Kamphausen, Thilo ; Fischer, Gunter ; Hacker, Jörg ; Rösch, Paul ; Faber, Cornelius:
Domain Motions of the Mip Protein from Legionella pneumophila.
In: Biochemistry. Bd. 45 (2006) Heft 40 . - S. 12303-12311.
DOI: https://doi.org/10.1021/bi060818i

Prasch, Stefan J. ; Schwarz, Sabine ; Eisenmann, Anke ; Wöhrl, Birgitta M. ; Schweimer, Kristian ; Rösch, Paul:
Interaction of the Intrinsically Unstructured Phage λ N Protein with Escherichia coli NusA.
In: Biochemistry. Bd. 45 (2006) Heft 14 . - S. 4542-4549.
DOI: https://doi.org/10.1021/bi0523411

Rao Jampani, Nageswara ; Neumann, Liane ; Wenzel, Sabine ; Schweimer, Kristian ; Rösch, Paul ; Wöhrl, Birgitta M.:
Structural studies on the RNA-recognition motif of NELF E, a cellular negative transcription elongation factor involved in the regulation of HIV transcription.
In: Biochemical Journal. Bd. 400 (2006) Heft 3 . - S. 449-456.
DOI: https://doi.org/10.1042/BJ20060421

Lehmann, Katrin ; Schweimer, Kristian ; Reese, Gerald ; Randow, Stefanie ; Suhr, Martin ; Becker, Wolf-Meinhard ; Vieths, Stefan ; Rösch, Paul:
Structure and stability of 2s albumin-type peanut allergens : implications for the severity of peanut allergic reactions.
In: Biochemical Journal. Bd. 395 (2006) Heft 3 . - S. 463-472.
DOI: https://doi.org/10.1042/BJ20051728

2005

Hofmann, Gregor ; Schweimer, Kristian ; Kiessling, Anke ; Hofinger, Edith ; Bauer, Finn ; Hoffmann, Silke ; Rösch, Paul ; Campbell, Iain D. ; Werner, Jörn M. ; Sticht, Heinrich:
Binding, domain orientation and dynamics of the Lck SH3-SH2 domain pair and comparison with other Src-family kinases.
In: Biochemistry. Bd. 44 (2005) Heft 39 . - S. 13043-13050.
DOI: https://doi.org/10.1021/bi050814y

Eisenmann, Anke ; Schwarz, Sabine ; Prasch, Stefan J. ; Schweimer, Kristian ; Rösch, Paul:
The E. coli NusA carboxy-terminal domains are structurally similar and show specific RNAP- and λN interaction.
In: Protein Science. Bd. 14 (2005) Heft 8 . - S. 2018-2019.
DOI: https://doi.org/10.1110/ps.051372205

Wöhrl, Birgitta M. ; Loubière, Laurence ; Brundiers, Ralf ; Goody, Roger S. ; Klatzmann, David ; Konrad, Manfred:
Expressing engineered thymidylate kinase variants in human cells to improve AZT phosphorylation and human immunodeficiency virus inhibition.
In: Journal of General Virology. Bd. 86 (2005) Heft 3 . - S. 757-764.
DOI: https://doi.org/10.1099/vir.0.80529-0

Horstmann, Martin ; Kamphausen, Thilo ; Schweimer, Kristian ; Steinert, Michael ; Hacker, Jörg ; Haase, Axel ; Rösch, Paul ; Schweimer, Gunter ; Faber, Cornelius:
¹H, ¹³C, ¹⁵N backbone and sidechain resonance assignment of Mip⁽⁷⁷⁻²¹³⁾ the PPIase domain of the Legionella pneumophila Mip protein.
In: Journal of Biomolecular NMR. Bd. 31 (2005) Heft 1 . - S. 77-78.
DOI: https://doi.org/10.1007/s10858-004-6041-6

Bauer, Finn ; Schweimer, Kristian ; Meiselbach, Heike ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich:
Structural characterization of Lyn-SH3 domain in complex with a herpesviral protein reveals an extended recognition motif that enhances binding affinity.
In: Protein Science. Bd. 14 (2005) Heft 10 . - S. 2487-2498.
DOI: https://doi.org/10.1110/ps.051563605

Marg, Bianca-Lucia ; Schweimer, Kristian ; Sticht, Heinrich ; Oesterhelt, Dieter:
A Two-α-Helix Extra Domain Mediates the Halophilic Character of a Plant-Type Ferredoxin from Halophilic Archaea.
In: Biochemistry. Bd. 44 (2005) Heft 1 . - S. 29-39.
DOI: https://doi.org/10.1021/bi0485169

2004

Bauer, Finn ; Hofinger, Edith ; Hoffmann, Silke ; Rösch, Paul ; Schweimer, Kristian ; Sticht, Heinrich:
Characterization of Lck-binding elements in the herpesviral regulatory Tip protein.
In: Biochemistry. Bd. 43 (2004) Heft 47 . - S. 14932-14939.
DOI: https://doi.org/10.1021/bi0485068

Faltz, Heike ; Bender, Christoph ; Wöhrl, Birgitta M. ; Vogel‐Bachmayr, Karin ; Hübscher, Ullrich ; Ramadan, Kristijan ; Liebscher, Jürgen:
Double Cyclization of Bis(α‐hetarylmethyl)amino Esters to Optically Active Bridged N‐Heterocycles of HIV‐Inhibiting Activitv.
In: European Journal of Organic Chemistry. (2004) Heft 16 . - S. 3484-3496.
DOI: https://doi.org/10.1002/ejoc.200400136

Eisenmann, Anke ; Schwarz, Sabine ; Rösch, Paul ; Schweimer, Kristian:
Sequence-Specific ¹H, ¹³C, ¹⁵N Resonance Assignments and Secondary Structure of the Carboxyterminal Domain of the E. coli Transcription Factor NusA.
In: Journal of Biomolecular NMR. Bd. 28 (2004) Heft 2 . - S. 193-194.
DOI: https://doi.org/10.1023/B:JNMR.0000013819.55179.13

Lehmann, Katrin ; Schweimer, Kristian ; Neudecker, Philipp ; Rösch, Paul:
Sequence-specific ¹H,¹³C and ¹⁵N resonance assignments of Ara h 6, an allergenic 2S albumin from peanut.
In: Journal of Biomolecular NMR. Bd. 29 (2004) Heft 1 . - S. 93-94.
DOI: https://doi.org/10.1023/B:JNMR.0000019459.57344.ce

Neudecker, Philipp ; Nerkamp, Jörg ; Eisenmann, Anke ; Nourse, Amanda ; Lauber, Thomas ; Schweimer, Kristian ; Lehmann, Katrin ; Schwarzinger, Stephan ; Ferreira, Fátima ; Rösch, Paul:
Solution structure, dynamics, and hydrodynamics of the calcium-bound cross-reactive birch pollen allergen Bet v 4 reveal a canonical monomeric two EF-hand assembly with a regulatory function.
In: Journal of Molecular Biology. Bd. 336 (2004) Heft 5 . - S. 1141-1157.
DOI: https://doi.org/10.1016/j.jmb.2003.12.070

2003

Wöhrl, Birgitta M.:
Antiterminationskomplexe als Ziel neuer Therapeutika.
In: Retrovirus-Bulletin. (2003) Heft 2 . - S. 4-6.

Lauber, Thomas ; Schulz, Axel ; Schweimer, Kristian ; Adermann, Knut ; Marx, Ute C.:
Homologous Proteins with Different Folds : The Three-Dimensional Structures of Domains 1 and 6 of the Multiple Kazal-Type Inhibitor LEKTI.
In: Journal of Molecular Biology. Bd. 328 (2003) Heft 1 . - S. 205-219.
DOI: https://doi.org/10.1016/S0022-2836(03)00245-6

Rothwell, P. J. ; Berger, S. ; Kensch, O. ; Felekyan, S. ; Antonik, M. ; Wöhrl, Birgitta M. ; Restle, Tobias ; Goody, Roger S. ; Seidel, C. A. M.:
Multiparameter single-molecule fluorescence spectroscopy reveals heterogeneity of HIV-1 reverse transcriptase:primer/template complexes.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 100 (2003) Heft 4 . - S. 1655-1660.
DOI: https://doi.org/10.1073/pnas.0434003100

Roda, Ricardo H. ; Balakrishnan, Mini ; Hanson, Mark N. ; Wöhrl, Birgitta M. ; Le Grice, Stuart F. J. ; Roques, Bernhard P. ; Gorelick, Robert J. ; Bambara, Robert A.:
Role of the reverse transcriptase, nucleocapsid protein and template structure in the two-step transfer mechanism in retroviral recombination.
In: The Journal of Biological Chemistry. Bd. 278 (2003) Heft 34 . - S. 31536-31546.
DOI: https://doi.org/10.1074/jbc.M304608200

Schweimer, Kristian ; Kiessling, Anke ; Bauer, Finn ; Hör, Simon ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich:
Sequence-specific ¹H, ¹³C and ¹⁵N resonance assignments of the SH3-SH2 domain pair from the human tyrosine kinase Lck.
In: Journal of Biomolecular NMR. Bd. 27 (2003) Heft 4 . - S. 405-406.
DOI: https://doi.org/10.1023/A:1025861326222

2002

Hollinderbäumer, Britta ; Wöhrl, Birgitta M.:
Resistenzmechanismen von HIV.
In: Bioforum. Bd. 25 (2002) . - S. 406-408.

Schweimer, Kristian ; Hoffmann, Silke ; Bauer, Finn ; Friedrich, Ute ; Kardinal, Christian ; Feller, Stephan M. ; Biesinger, Brigitte ; Sticht, Heinrich:
Structural investigation of the binding of a herpesviral protein to the SH3 domain of tyrosine kinase Lck.
In: Biochemistry. Bd. 41 (2002) Heft 16 . - S. 5120-5130.
DOI: https://doi.org/10.1021/bi015986j

Werner, Susanne ; Hindmarsh, Patrick ; Napirei, Markus ; Vogel-Bachmayr, Karin ; Wöhrl, Birgitta M.:
Subcellular localization and integration activities of Rous Sarcoma Virus reverse transcriptase.
In: Journal of Virology. Bd. 76 (2002) Heft 12 . - S. 6205-6212.
DOI: https://doi.org/10.1128/JVI.76.12.6205-6212.2002

2001

Neudecker, Philipp ; Schweimer, Kristian ; Nerkamp, Jörg ; Scheurer, Stephan ; Vieths, Stefan ; Sticht, Heinrich ; Rösch, Paul:
Allergic cross-reactivity made visible : solution structure of the major cherry allergen Pru av 1.
In: The Journal of Biological Chemistry. Bd. 276 (2001) Heft 25 . - S. 22756-22763.
DOI: https://doi.org/10.1074/jbc.M101657200

Heger, Peter ; Lohmaier, Jens ; Schneider, Grit ; Schweimer, Kristian ; Stauber, Roland H.:
Qualitative highly divergent nuclear export signals can regulate export by the competition for transport cofactors in vivo.
In: Traffic. Bd. 2 (2001) Heft 8 . - S. 544-555.
DOI: https://doi.org/10.1034/j.1600-0854.2001.20804.x

Werner, Susanne ; Vogel-Bachmayr, Karin ; Hollinderbäumer, Britta ; Wöhrl, Birgitta M.:
Requirements for Minus-Strand Transfer Catalyzed by Rous Sarcoma Virus Reverse Transcriptase.
In: Journal of Virology. Bd. 75 (2001) Heft 21 . - S. 10132-10138.
DOI: https://doi.org/10.1128/JVI.75.21.10132-10138.2001

Bauer, Finn ; Schweimer, Kristian ; Klüver, Enno ; Conejo-Garcia, Jose-Ramon ; Forssmann, Wolf-Georg ; Rösch, Paul ; Adermann, Knut ; Sticht, Heinrich:
Structure determination of human and murine β-defensins reveals structural conservation in the absence of significant sequence similarity.
In: Protein Science. Bd. 10 (2001) Heft 12 . - S. 2470-2479.
DOI: https://doi.org/10.1110/ps.24401

2000

Schärpf, Manuela ; Sticht, Heinrich ; Schweimer, Kristian ; Boehm, Markus ; Hoffmann, Silke ; Rösch, Paul:
Antitermination in bacteriophage λ : the structure of the N36 peptide-boxB RNA complex.
In: European Journal of Biochemistry. Bd. 267 (2000) Heft 8 . - S. 2397-2408.
DOI: https://doi.org/10.1046/j.1432-1327.2000.01251.x

Schweimer, Kristian ; Marg, Bianca-Lucia ; Oesterhelt, Dieter ; Rösch, Paul ; Sticht, Heinrich:
Sequence-specific 1H, 13C and 15N resonance assignments and secondary structure of [2Fe-2S] ferredoxin from Halobacterium salinarum.
In: Journal of Biomolecular NMR. Bd. 16 (2000) Heft 4 . - S. 347-348.
DOI: https://doi.org/10.1023/A:1008381016258

Neudecker, Philipp ; Schweimer, Kristian ; Nerkamp, Jörg ; Boehm, Markus ; Scheurer, Stephan ; Vieths, Stefan ; Sticht, Heinrich ; Rösch, Paul:
Sequence-specific 1H, 13C and 15N resonance assignments of the major cherry allergen Pru a 1.
In: Journal of Biomolecular NMR. Bd. 18 (2000) Heft 1 . - S. 71-72.
DOI: https://doi.org/10.1023/A:1008357100592

Schweimer, Kristian ; Hoffmann, Silke ; Rösch, Paul ; Sticht, Heinrich ; Wastl, Jürgen ; Maier, Uwe-G.:
Solution structure of a zinc substituted eukaryotic rubredoxin from the cryptomonad alga Guillardia theta.
In: Protein Science. Bd. 9 (2000) Heft 8 . - S. 1474-1486.
DOI: https://doi.org/10.1110/ps.9.8.1474

Faber, Cornelius ; Sticht, Heinrich ; Schweimer, Kristian ; Rösch, Paul:
Structural Rearrangements of HIV-1 Tat-responsive RNA upon Binding of Neomycin B.
In: The Journal of Biological Chemistry. Bd. 275 (2000) Heft 27 . - S. 20660-20666.
DOI: https://doi.org/10.1074/jbc.M000920200

Kensch, Oliver ; Restle, Tobias ; Wöhrl, Birgitta M. ; Goody, Roger S. ; Steinhoff, Heinz-Jürgen:
Temperature-dependent equilibrium between the open and closed conformation of the p66 subunit of the HIV-1 reverse transcriptase revealed by site-directed spin labelling.
In: Journal of Molecular Biology. Bd. 301 (2000) Heft 4 . - S. 1029-1039.
DOI: https://doi.org/10.1006/jmbi.2000.3998

1999

Schweimer, Kristian ; Sticht, Heinrich ; Nerkamp, Jörg ; Boehm, Markus ; Breitenbach, Michael ; Vieths, Stefan ; Rösch, Paul:
NMR Spectroscopy Reveals Common Structural Features of the Birch Pollen Allergen Bet v 1 and the Cherry Allergen Pru a 1.
In: Applied Magnetic Resonance. Bd. 17 (1999) . - S. 449-464.
DOI: https://doi.org/10.1007/BF03162177

Sticht, Heinrich ; Escher, Sylvia E. ; Schweimer, Kristian ; Forssmann, Wolf-Georg ; Rösch, Paul ; Adermann, Knut:
Solution structure of the human CC chemokine 2 : A monomeric representative of the CC chemokine subtype.
In: Biochemistry. Bd. 38 (1999) Heft 19 . - S. 5995-6002.
DOI: https://doi.org/10.1021/bi990065i

1998

Souquet, Manfred ; Restle, Tobias ; Krebs, Ruth ; Le Grice, Stuart F.J. ; Goody, Roger S. ; Wöhrl, Birgitta M.:
Analysis of the polymerization kinetics of homodimeric EIAV p51/51 reverse transcriptase implies the formation of a polymerase active site identical to heterodimeric EIAV p66/51 reverse transcriptase.
In: Biochemistry. Bd. 37 (1998) Heft 35 . - S. 12144-12152.
DOI: https://doi.org/10.1021/bi9731596

Sieber, Petra ; Lindemann, Almut ; Boehm, Markus ; Seidel, Gabi ; Herzing, Ulrike ; van der Heusen, Peter ; Müller, Rainer ; Rüger, Wolfgang ; Jaenicke, Rainer ; Rösch, Paul:
Overexpression and structural characterization of the phage T4 protein DsbA.
In: Biological Chemistry. Bd. 379 (1998) Heft 1 . - S. 51-58.
DOI: https://doi.org/10.1515/bchm.1998.379.1.51

Krebs, Ruth ; Wöhrl, Birgitta M. ; Cellai, Luciano ; Goody, Roger S. ; Restle, Tobias:
Pre-steady-state kinetic characterization of RNA-primed initiation of transcription by HIV-1 reverse transcriptase and analysis of the transition to a processive DNA-primed polymerization mode.
In: Biochemistry. Bd. 37 (1998) Heft 38 . - S. 13349-13358.
DOI: https://doi.org/10.1021/bi981102t

1997

Wöhrl, Birgitta M. ; Krebs, Ruth ; Thrall, Sara H. ; Le Grice, Stuart F.J. ; Scheidig, Axel J. ; Goody, Roger S.:
Kinetic analysis of four HIV-1 reverse transcriptase enzymes mutated in the primer grip grip region of p66 : implications for DNA synthesis and dimerization.
In: The Journal of Biological Chemistry. Bd. 272 (1997) . - S. 17581-17587.
DOI: https://doi.org/10.1074/jbc.272.28.17581

Krebs, Ruth ; Immendörfer, Ulrike ; Thrall, Sara H. ; Wöhrl, Birgitta M. ; Goody, Roger S.:
Single-Step Kinetics of HIV-1 Reverse Transcriptase Mutants Responsible for Virus Resistance to Nucleoside Inhibitors Zidovudine and 3-TC.
In: Biochemistry. Bd. 36 (1997) Heft 33 . - S. 10292-10300.
DOI: https://doi.org/10.1021/bi970512z

1996

Arts, Eric J. ; Stetor, S. R. ; Li, X. ; Rausch, J. W. ; Howard, K. J. ; Ehresmann, Bernard ; North, T. W. ; Wöhrl, Birgitta M. ; Goody, Roger S. ; Wainberg, M. A. ; Grice, S. F. J.:
Initiation of (-) strand DNA synthesis from tRNA(3Lys) on lentiviral RNAs : Implications of specific HIV-1 RNA-tRNA(3Lys) interactions inhibiting primer utilization by retroviral reverse transcriptases.
In: Proceedings of the National Academy of Sciences of the United States of America. Bd. 93 (1996) Heft 19 . - S. 10063-10068.
DOI: https://doi.org/10.1073/pnas.93.19.10063

Rausch, Jason W. ; Arts, Eric J. ; Wöhrl, Birgitta M. ; Le Grice, Stuart F.J.:
Involvement of C-terminal structural elements of Equine Infectious Anemia Virus reverse transcriptase in DNA polymerase and ribonuclease H activities.
In: Journal of Molecular Biology. Bd. 257 (1996) Heft 3 . - S. 500-511.
DOI: https://doi.org/10.1006/jmbi.1996.0181

Metzger, Armin U. ; Schindler, Thomas ; Willbold, Dieter ; Kraft, Margot ; Steegborn, Clemens ; Volkmann, Andrea ; Frank, Rainer W. ; Rösch, Paul:
Structural rearrangements on HIV-1 Tat (32-72) TAR complex formation.
In: FEBS Letters. Bd. 384 (1996) Heft 3 . - S. 255-259.
DOI: https://doi.org/10.1016/0014-5793(96)00314-6

Willbold, Dieter ; Volkmann, Andrea ; Metzger, Armin U. ; Sticht, Heinrich ; Rosin-Arbesfeld, Rina ; Gazit, Arnona ; Yaniv, Abraham ; Frank, Rainer W. ; Rösch, Paul:
Structural Studies of the Equine Infectious Anemia Virus trans-activator Protein.
In: European Journal of Biochemistry. Bd. 240 (1996) Heft 1 . - S. 45-52.
DOI: https://doi.org/10.1111/j.1432-1033.1996.0045h.x

1995

Wöhrl, Birgitta M. ; Tantillo, Chris ; Arnold, Edward ; Le Grice, Stuart F.J.:
An Expanded Model of Replicating Human Immunodeficiency Virus Reverse Transcriptase.
In: Biochemistry. Bd. 34 (1995) Heft 16 . - S. 5343-5350.
DOI: https://doi.org/10.1021/bi00016a005

Wöhrl, Birgitta M. ; Georgiadis, M. M. ; Telesnitsky, A. ; Hendrickson, W. A. ; Le Grice, Stuart F. J.:
Footprint analysis of replicating murine leukemia virus reverse transcriptase.
In: Science. Bd. 267 (1995) Heft 5194 . - S. 96-99.
DOI: https://doi.org/10.1126/science.7528942

Wildegger, Gudrun ; Bentrop, Detlef ; Ejchart, Andrzej ; Alber, Markus ; Hage, Andrea ; Sterner, Reinhard ; Rösch, Paul:
¹H Nuclear‐Magnetic‐Resonance Investigation of Oxidized Fe₄S₄ Ferredoxin from Thermotoga maritima : Hyperfine‐Shifted Resonances, Sequence‐Specific Assignments and Secondary Structure.
In: European Journal of Biochemistry. Bd. 229 (1995) Heft 3 . - S. 658-668.
DOI: https://doi.org/10.1111/j.1432-1033.1995.0658j.x

Wehmeier, Udo F. ; Wöhrl, Birgitta M. ; Lengeler, Joseph W.:
Molecular analysis of the phosphoenolpyruvate-dependent L-sorbose : phosphotransferase system from Klebsiella pneumoniae and of its multidomain structure.
In: Molecular and General Genetics. Bd. 246 (1995) Heft 5 . - S. 610-618.
DOI: https://doi.org/10.1007/BF00298968

1994

Volltext
Wöhrl, Birgitta M. ; Howard, Kathryn J. ; Jacques, Pamela S. ; Le Grice, Stuart F.J.:
Alternative modes of polymerization distinguish the subunits of equine infectious anemia virus reverse transcriptase.
In: The Journal of Biological Chemistry. Bd. 269 (1994) Heft 11 . - S. 8541-8548.

Volltext
Jacques, Pamela S. ; Wöhrl, Birgitta M. ; Howard, Kathryn J. ; Le Grice, Stuart F.J.:
Modulation of HIV-1 reverse transcriptase function in "selectively deleted" p66/p51 heterodimers.
In: The Journal of Biological Chemistry. Bd. 269 (1994) Heft 2 . - S. 1388-1393.

Volltext
Jacques, Pamela S. ; Wöhrl, Birgitta M. ; Ottmann, Michele ; Darlix, Jean-Luc ; Le Grice, Stuart F.J.:
Mutating the "primer grip" of p66 HIV-1 reverse transcriptase implicates Tryptophan-229 in template-primer utilization.
In: The Journal of Biological Chemistry. Bd. 269 (1994) Heft 42 . - S. 26472-26478.

1993

Volltext
Volkmann, Silke ; Wöhrl, Birgitta M. ; Tisdale, Margaret ; Moelling, Karin:
Enzymatic analysis of two HIV-1 reverse transcriptase mutants with mutations in carboxyl-terminal amino acid residues conserved among retroviral ribonucleases H.
In: The Journal of Biological Chemistry. Bd. 268 (1993) Heft 4 . - S. 2674-2683.

Volltext
Wöhrl, Birgitta M. ; Ehresmann, Bernard ; Keith, Gerhard ; Le Grice, Stuart F.J.:
Nuclease footprinting of human immunodeficiency virus reverse transcriptase/tRNA(Lys-3) complexes.
In: The Journal of Biological Chemistry. Bd. 268 (1993) Heft 18 . - S. 13617-13624.

1992

Volltext
Richter-Cook, Nancy J. ; Howard, Kathryn J. ; Cirino, Nick M. ; Wöhrl, Birgitta M. ; Le Grice, Stuart F.J.:
Interaction of tRNA(Lys-3) with multiple forms of human immunodeficiency virus reverse transcriptase.
In: The Journal of Biological Chemistry. Bd. 267 (1992) Heft 22 . - S. 15952-15957.

Le Grice, Stuart F. J. ; Richter-Cook, Nancy J. ; Cirino, Nick M. ; Howard, K. J. ; Wöhrl, Birgitta M. ; Barat, C. ; Naas, T. ; Schatz, O. ; Darlix, J.-L.:
Role of HIV reverse transcriptase subunits in enzyme structure and function.
In: Lilley, David M.J. ; Heumann, Hermann ; Suck, Dietrich (Hrsg.): Structural tools for the analysis of protein-nucleic acid complexes editor. - Basel : Birkhäuser Verlag, 1992 . - S. 369-390

1991

Wöhrl, Birgitta M. ; Volkmann, Silke ; Moelling, Karin:
Mutations of a conserved residue within HIV-1 ribonuclease H affect its exo- and endonuclease activities.
In: Journal of Molecular Biology. Bd. 220 (1991) Heft 3 . - S. 801-818.
DOI: https://doi.org/10.1016/0022-2836(91)90119-Q

Moelling, Karin ; Wöhrl, Birgitta M. ; Tisdale, Margaret ; Volkmann, Silke ; Goren, I.:
RNase H as potential target for antiviral drugs.
In: Wissenschaftliche Zeitschrift der Humboldt-Universität zu Berlin : Reihe Medizin. (1991) Heft 4 . - S. 15-19.

1990

Wöhrl, Birgitta M. ; Lengeler, Joseph W.:
Cloning and physical mapping of the sor genes for L‐sorbose transport and metabolism from Klebsiella pneumoniae.
In: Molecular Microbiology. Bd. 4 (1990) Heft 9 . - S. 1557-1565.
DOI: https://doi.org/10.1111/j.1365-2958.1990.tb02067.x

Wöhrl, Birgitta M. ; Sprenger, Georg A. ; Lengeler, Joseph W.:
Construction of a new catabolic pathway for D-fructose in Escherichia coli K12 using an L-sorbose-specific enzyme from Klebsiella pneumoniae.
In: Archives of Microbiology. Bd. 154 (1990) Heft 2 . - S. 162-167.
DOI: https://doi.org/10.1007/BF00423327

Wöhrl, Birgitta M. ; Moelling, Karin:
Interaction of HIV-1 ribonuclease H with polypurine tract containing RNA-DNA hybrids.
In: Biochemistry. Bd. 29 (1990) Heft 44 . - S. 10141-10147.
DOI: https://doi.org/10.1021/bi00496a001

Wöhrl, Birgitta M. ; Wehmeier, Udo F. ; Lengeler, Joseph W.:
Positive and negative regulation of expression of the L-sorbose (sor) operon by SorC in Klebsiella pneumoniae.
In: Molecular and General Genetics. Bd. 224 (1990) Heft 2 . - S. 193-200.
DOI: https://doi.org/10.1007/BF00271552

Lengeler, Joseph W. ; Titgemeyer, F. ; Vogler, A. P. ; Wöhrl, Birgitta M.:
Structure and homologies of carbohydrate : phosphotransferase system (PTS) proteins.
In: Philosophical Transactions of the Royal Society B: Biological Sciences. Bd. 326 (1990) Heft 1236 . - S. 489-504.
DOI: https://doi.org/10.1098/rstb.1990.0027

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