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Faculties > Faculty of Biology, Chemistry and Earth Sciences > Department of Chemistry > Chair Biochemistry > Chair Biochemistry - Univ.-Prof. Dr. Andreas Möglich

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Article in a journal

Volltext
Möglich, Andreas:
Signal transduction in photoreceptor histidine kinases.
In: Protein Science. (9 August 2019) .
DOI: https://doi.org/10.1002/pro.3705

Stüven, Birthe ; Stabel, Robert ; Ohlendorf, Robert ; Beck, Julian ; Schubert, Roman ; Möglich, Andreas:
Characterization and engineering of photoactivated adenylyl cyclases.
In: Biological Chemistry. Vol. Online first (9 January 2019) .
DOI: https://doi.org/10.1515/hsz-2018-0375

Weber, Anna M. ; Kaiser, Jennifer ; Ziegler, Thea ; Pilsl, Sebastian ; Renzl, Christian ; Sixt, Lisa ; Pietruschka, Georg ; Moniot, Sébastien ; Kakoti, Ankana ; Juraschitz, Marc ; Schrottke, Stefanie ; Lledo Bryant, Laura ; Steegborn, Clemens ; Bittl, Robert ; Mayer, Günter ; Möglich, Andreas:
A blue light receptor that mediates RNA binding and translational regulation.
In: Nature Chemical Biology. (2019) .
DOI: https://doi.org/10.1038/s41589-019-0346-y

Baumann, Tobias ; Hauf, Matthias ; Richter, Florian ; Albers, Suki ; Möglich, Andreas ; Ignatova, Zoya ; Budisa, Nediljko:
Computational Aminoacyl-tRNA Synthetase Library Design for Photocaged Tyrosine.
In: International Journal of Molecular Sciences. Vol. 20 (2019) Issue 9 . - p. 2343.
DOI: https://doi.org/10.3390/ijms20092343

Raju, Diana N. ; Hansen, Jan N. ; Rassmann, Sebastian ; Stüven, Birthe ; Jikeli, Jan F. ; Strünker, Timo ; Körschen, Heinz G. ; Möglich, Andreas ; Wachten, Dagmar:
Cyclic Nucleotide-Specific Optogenetics Highlights Compartmentalization of the Sperm Flagellum into cAMP Microdomains.
In: Cells. Vol. 8 (2019) Issue 7 . - p. 648.
DOI: https://doi.org/10.3390/cells8070648

Golonka, David ; Fischbach, Patrick ; Jena, Siddhartha G. ; Kleeberg, Julius R. W. ; Essen, Lars-Oliver ; Toettcher, Jared E. ; Zurbriggen, Matias D. ; Möglich, Andreas:
Deconstructing and repurposing the light-regulated interplay between Arabidopsis phytochromes and interacting factors.
In: Communications Biology. Vol. 2 (2019) . - Art.Nr. 448.
DOI: https://doi.org/10.1038/s42003-019-0687-9

Möglich, Andreas ; Janovjak, Harald:
Editorial overview : Synthetic sensors and signals : new tools for a new trade.
In: Current Opinion in Structural Biology. Vol. 57 (2019) . - S. iii-v.
DOI: https://doi.org/10.1016/j.sbi.2019.07.005

Dietler, Julia ; Stabel, Robert ; Möglich, Andreas:
Pulsatile illumination for photobiology and optogenetics.
In: Methods in Enzymology. (2019) .
DOI: https://doi.org/10.1016/bs.mie.2019.04.005

Stabel, Robert ; Stüven, Birthe ; Hansen, Jan Niklas ; Körschen, Heinz G. ; Wachten, Dagmar ; Möglich, Andreas:
Revisiting and Redesigning Light-Activated Cyclic-Mononucleotide Phosphodiesterases.
In: Journal of Molecular Biology. (2019) .
DOI: https://doi.org/10.1016/j.jmb.2019.07.011

Möglich, Andreas:
An Open-Source, Cross-Platform Resource for Nonlinear Least-Squares Curve Fitting.
In: Journal of Chemical Education. (9 October 2018) . - Article ASAP.
DOI: https://doi.org/10.1021/acs.jchemed.8b00649

Losi, Aba ; Gardner, Kevin H. ; Möglich, Andreas:
Blue-Light Receptors for Optogenetics.
In: Chemical Reviews. (9 July 2018) . - Article ASAP.
DOI: https://doi.org/10.1021/acs.chemrev.8b00163

Volltext
Hennemann, Julia ; Iwasaki, Roman S. ; Grund, Tamara N. ; Diensthuber, Ralph P. ; Richter, Florian ; Möglich, Andreas:
Optogenetic Control by Pulsed Illumination.
In: ChemBioChem. (2018) .
DOI: https://doi.org/10.1002/cbic.201800030

Möglich, Andreas:
Signaltransduktion einer lichtregulierten Sensorhistidinkinase.
In: Nachrichten aus der Chemie. Vol. 66 (2018) Issue 2 . - pp. 123-126.
DOI: https://doi.org/10.1002/nadc.20184058953

Engelhard, Christopher ; Diensthuber, Ralph P. ; Möglich, Andreas ; Bittl, Robert:
Blue-light reception through quaternary transitions.
In: Scientific Reports. Vol. 7 (2017) Issue 1 . - Article number 1385.
DOI: https://doi.org/10.1038/s41598-017-01497-7

Volltext

Stabel, Robert ; Möglich, Andreas:
Die Kontrolle zyklischer Nukleotide mittels Licht.
In: BIOspektrum. Vol. 23 (2017) Issue 4 . - pp. 384-387.
DOI: https://doi.org/10.1007/s12268-017-0813-5

Nack, Jennifer ; Möglich, Andreas:
Optische Kontrolle zellulärer Prozesse.
In: Nachrichten aus der Chemie. Vol. 65 (2017) Issue 3 . - pp. 309-313.
DOI: https://doi.org/10.1002/nadc.20174060764

Hauf, Mathias ; Richter, Florian ; Schneider, Tobias ; Faidt, Thomas ; Martins, Berta M. ; Baumann, Tobias ; Durkin, Patrick ; Dobbek, Holger ; Jacobs, Karin ; Möglich, Andreas ; Budisa, Nediljko:
Photoactivatable mussel-based underwater adhesive proteins by an expanded genetic code.
In: ChemBioChem. (2017) .
DOI: https://doi.org/10.1002/cbic.201700327

Stabel, Robert ; Stüven, Birthe ; Ohlendorf, Robert ; Möglich, Andreas:
Primer-Aided Truncation for the Creation of Hybrid Proteins.
In: Methods in Molecular Biology. Vol. 1596 (2017) . - pp. 287-304.
DOI: https://doi.org/10.1007/978-1-4939-6940-1_18

Volltext
Berntsson, Oskar ; Diensthuber, Ralph P. ; Panman, Matthijs R. ; Björling, Alexander ; Gustavsson, Emil ; Hoernke, Maria ; Hughes, Ashley J. ; Henry, Léocadie ; Niebling, Stephan ; Takala, Heikki ; Ihalainen, Janne A. ; Newby, Gemma ; Kerruth, Silke ; Heberle, Joachim ; Liebi, Marianne ; Menzel, Andreas ; Henning, Robert ; Kosheleva, Irina ; Möglich, Andreas ; Westenhoff, Sebastian:
Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase.
In: Nature Communications. Vol. 8 (2017) . - No. 284.
DOI: https://doi.org/10.1038/s41467-017-00300-5

Richter, Florian ; Fonfara, Ines ; Gelfert, Renate ; Nack, Jennifer ; Charpentier, Emmanuelle ; Möglich, Andreas:
Switchable Cas9.
In: Current Opinion in Biotechnology. Vol. 48 (2017) . - pp. 119-126.
DOI: https://doi.org/10.1016/j.copbio.2017.03.025

Berntsson, Oskar ; Diensthuber, Ralph P. ; Panman, Matthijs R. ; Björling, Alexander ; Hughes, Ashley J. ; Henry, Léocadie ; Niebling, Stephan ; Newby, Gemma ; Liebi, Marianne ; Menzel, Andreas ; Henning, Robert ; Kosheleva, Irina ; Möglich, Andreas ; Westenhoff, Sebastian:
Time-Resolved X-Ray Solution Scattering Reveals the Structural Photoactivation of a Light-Oxygen-Voltage Photoreceptor.
In: Structure. Vol. 25 (2017) . - pp. 1-6.
DOI: https://doi.org/10.1016/j.str.2017.04.006

Ohlendorf, Robert ; Schumacher, Charlotte Helene ; Richter, Florian ; Möglich, Andreas:
Library-Aided Probing of Linker Determinants in Hybrid Photoreceptors.
In: ACS Synthetic Biology. (21 March 2016) .
DOI: https://doi.org/10.1021/acssynbio.6b00028

Volltext
Richter, Florian ; Fonfara, Ines ; Bouazza, Boris ; Schumacher, Charlotte Helene ; Bratovič, Majda ; Charpentier, Emmanuelle ; Möglich, Andreas:
Engineering of temperature- and light-switchable Cas9 variants.
In: Nucleic Acids Research. Vol. 44 (2016) Issue 20 . - pp. 10003-10014.
DOI: https://doi.org/10.1093/nar/gkw930

Schumacher, Charlotte Helene ; Körschen, Heinz G. ; Nicol, Christopher ; Gasser, Carlos ; Seifert, Reinhard ; Schwärzel, Martin ; Möglich, Andreas:
A Fluorometric Activity Assay for Light-Regulated Cyclic-Nucleotide-Monophosphate Actuators.
In: Methods in Molecular Biology. Vol. 1408 (2016) . - pp. 93-105.
DOI: https://doi.org/10.1007/978-1-4939-3512-3_7

Ziegler, Thea ; Schumacher, Charlotte Helene ; Möglich, Andreas:
Guidelines for Photoreceptor Engineering.
In: Methods in Molecular Biology. Vol. 1408 (2016) . - pp. 389-403.
DOI: https://doi.org/10.1007/978-1-4939-3512-3_27

Volltext
Yee, Estelle F. ; Diensthuber, Ralph P. ; Vaidya, Anand T. ; Borbat, Peter P. ; Engelhard, Christopher ; Freed, Jack H,. ; Bittl, Robert ; Möglich, Andreas ; Crane, Brian R.:
Signal transduction in light-oxygen-voltage receptors lacking the adduct-forming cysteine residue.
In: Nature Communications. Vol. 6 (9 December 2015) . - p. 10079.
DOI: https://doi.org/10.1038/ncomms10079

Ziegler, Thea ; Möglich, Andreas:
Photoreceptor engineering.
In: Frontiers in Molecular Biosciences. Vol. 2 (17 June 2015) . - p. 30. - 25 S..
DOI: https://doi.org/10.3389/fmolb.2015.00030

Richter, Florian ; Scheib, Ulrike ; Mehlhorn, Jennifer ; Schubert, Roman ; Wietek, Jonas ; Gernetzki, Oliver ; Hegemann, Peter ; Mathes, Tilo ; Möglich, Andreas:
Upgrading a microplate reader for photobiology and all-optical experiments.
In: Photochemical & Photobiological Sciences. Vol. 14 (February 2015) Issue 2 . - pp. 270-279.
DOI: https://doi.org/10.1039/c4pp00361f

Diensthuber, Ralph P. ; Engelhard, Christopher ; Lemke, Nora ; Gleichmann, Tobias ; Ohlendorf, Robert ; Bittl, Robert ; Möglich, Andreas:
Biophysical, mutational, and functional investigation of the chromophore-binding pocket of light-oxygen-voltage photoreceptors.
In: ACS Synthetic Biology. Vol. 3 (21 November 2014) Issue 11 . - pp. 811-819.
DOI: https://doi.org/10.1021/sb400205x

Gasser, Carlos ; Taiber, Sandra ; Yeh, Chen-Min ; Wittig, Charlotte Helene ; Hegemann, Peter ; Ryu, Soojin ; Wunder, Frank ; Möglich, Andreas:
Engineering of a red-light-activated human cAMP/cGMP-specific phosphodiesterase.
In: Proceedings of the National Academy of Sciences of the United States of America. Vol. 111 (17 June 2014) Issue 24 . - pp. 8803-8808.
DOI: https://doi.org/10.1073/pnas.1321600111

Gleichmann, Tobias ; Diensthuber, Ralph P. ; Möglich, Andreas:
Charting the signal trajectory in a light-oxygen-voltage photoreceptor by random mutagenesis and covariance analysis.
In: The Journal of Biological Chemistry. Vol. 288 (11 October 2013) Issue 41 . - pp. 29345-29355.
DOI: https://doi.org/10.1074/jbc.M113.506139

Engelhard, Christopher ; Raffelberg, Sarah ; Tang, Yifen ; Diensthuber, Ralph P. ; Möglich, Andreas ; Losi, Aba ; Gärtner, Wolfgang ; Bittl, Robert:
A structural model for the full-length blue light-sensing protein YtvA from Bacillus subtilis, based on EPR spectroscopy.
In: Photochemical & Photobiological Sciences. Vol. 12 (October 2013) Issue 10 . - pp. 1855-1863.
DOI: https://doi.org/10.1039/c3pp50128k

Möglich, Andreas ; Hegemann, Peter:
Biotechnology : Programming genomes with light.
In: Nature. Vol. 500 (22 August 2013) Issue 7463 . - pp. 406-408.
DOI: https://doi.org/10.1038/500406a

Diensthuber, Ralph P. ; Bommer, Martin ; Gleichmann, Tobias ; Möglich, Andreas:
Full-length structure of a sensor histidine kinase pinpoints coaxial coiled coils as signal transducers and modulators.
In: Structure. Vol. 21 (2 July 2013) Issue 7 . - pp. 1127-1136.
DOI: https://doi.org/10.1016/j.str.2013.04.024

Diensthuber, Ralph P. ; Ohlendorf, Robert ; Gleichmann, Tobias ; Möglich, Andreas:
Lichtregulierte Genexpression.
In: BIOspektrum. Vol. 19 (February 2013) Issue 2 . - pp. 149-151.
DOI: https://doi.org/10.1007/s12268-013-0286-0

Rockwell, Nathan C. ; Ohlendorf, Robert ; Möglich, Andreas:
Cyanobacteriochromes in full color and three dimensions.
In: Proceedings of the National Academy of Sciences of the United States of America. Vol. 110 (15 January 2013) Issue 3 . - pp. 806-807.
DOI: https://doi.org/10.1073/pnas.1220690110

Ohlendorf, Robert ; Vidavski, Roee R. ; Eldar, Avigdor ; Moffat, Keith ; Möglich, Andreas:
From dusk till dawn : one-plasmid systems for light-regulated gene expression.
In: Journal of Molecular Biology. Vol. 416 (2 March 2012) Issue 4 . - pp. 534-542.
DOI: https://doi.org/10.1016/j.jmb.2012.01.001

Hegemann, Peter ; Möglich, Andreas:
Channelrhodopsin engineering and exploration of new optogenetic tools.
In: Nature Methods. Vol. 8 (January 2011) Issue 1 . - pp. 39-42.
DOI: https://doi.org/10.1038/nmeth.f.327

Möglich, Andreas ; Moffat, Keith:
Engineered photoreceptors as novel optogenetic tools.
In: Photochemical & Photobiological Sciences. Vol. 9 (28 October 2010) Issue 10 . - pp. 1286-1300.
DOI: https://doi.org/10.1039/c0pp00167h

Möglich, Andreas ; Ayers, Rebecca A. ; Moffat, Keith:
Addition at the molecular level : signal integration in designed Per-ARNT-Sim receptor proteins.
In: Journal of Molecular Biology. Vol. 400 (16 July 2010) Issue 3 . - pp. 477-486.
DOI: https://doi.org/10.1016/j.jmb.2010.05.019

Möglich, Andreas ; Yang, Xiaojing ; Ayers, Rebecca A. ; Moffat, Keith:
Structure and function of plant photoreceptors.
In: Annual Review of Plant Biology. Vol. 61 (2010) . - pp. 21-47.
DOI: https://doi.org/10.1146/annurev-arplant-042809-112259

Möglich, Andreas ; Ayers, Rebecca A. ; Moffat, Keith:
Structure and signaling mechanism of Per-ARNT-Sim domains.
In: Structure. Vol. 17 (14 October 2009) Issue 10 . - pp. 1282-1294.
DOI: https://doi.org/10.1016/j.str.2009.08.011

Möglich, Andreas ; Ayers, Rebecca A. ; Moffat, Keith:
Design and signaling mechanism of light-regulated histidine kinases.
In: Journal of Molecular Biology. Vol. 385 (6 February 2009) Issue 5 . - pp. 1433-1444.
DOI: https://doi.org/10.1016/j.jmb.2008.12.017

Möglich, Andreas ; Moffat, Keith:
Structural basis for light-dependent signaling in the dimeric LOV domain of the photosensor YtvA.
In: Journal of Molecular Biology. Vol. 373 (12 October 2007) Issue 1 . - pp. 112-126.
DOI: https://doi.org/10.1016/j.jmb.2007.07.039

Möglich, Andreas ; Joder, Karin ; Kiefhaber, Thomas:
End-to-end distance distributions and intrachain diffusion constants in unfolded polypeptide chains indicate intramolecular hydrogen bond formation.
In: Proceedings of the National Academy of Sciences of the United States of America. Vol. 103 (15 August 2006) Issue 33 . - pp. 12394-12399.
DOI: https://doi.org/10.1073/pnas.0604748103

Möglich, Andreas ; Weinfurtner, Daniel ; Gronwald, Wolfram ; Maurer, Till ; Kalbitzer, Hans Robert:
PERMOL : restraint-based protein homology modeling using DYANA or CNS.
In: Bioinformatics. Vol. 21 (1 May 2005) Issue 9 . - pp. 2110-2111.
DOI: https://doi.org/10.1093/bioinformatics/bti276

Krieger, Florian ; Möglich, Andreas ; Kiefhaber, Thomas:
Effect of proline and glycine residues on dynamics and barriers of loop formation in polypeptide chains.
In: Journal of the American Chemical Society. Vol. 127 (16 March 2005) Issue 10 . - pp. 3346-3352.
DOI: https://doi.org/10.1021/ja042798i

Möglich, Andreas ; Krieger, Florian ; Kiefhaber, Thomas:
Molecular basis for the effect of urea and guanidinium chloride on the dynamics of unfolded polypeptide chains.
In: Journal of Molecular Biology. Vol. 345 (7 January 2005) Issue 1 . - pp. 153-162.
DOI: https://doi.org/10.1016/j.jmb.2004.10.036

Möglich, Andreas ; Weinfurtner, Daniel ; Maurer, Till ; Gronwald, Wolfram ; Kalbitzer, Hans Robert:
A restraint molecular dynamics and simulated annealing approach for protein homology modeling utilizing mean angles.
In: BMC Bioinformatics. Vol. 6 (2005) . - p. 91.
DOI: https://doi.org/10.1186/1471-2105-6-91

Möglich, Andreas ; Koch, Brigitte ; Gronwald, Wolfram ; Hengstenberg, Wolfgang ; Brunner, Eike ; Kalbitzer, Hans Robert:
Solution structure of the active-centre mutant I14A of the histidine-containing phosphocarrier protein from Staphylococcus carnosus.
In: European Journal of Biochemistry. Vol. 271 (December 2004) Issue 23-24 . - pp. 4815-4824.
DOI: https://doi.org/10.1111/j.1432-1033.2004.04447.x

Martin, Georges ; Möglich, Andreas ; Keller, Walter ; Doublié, Sylvie:
Biochemical and structural insights into substrate binding and catalytic mechanism of mammalian poly(A) polymerase.
In: Journal of Molecular Biology. Vol. 341 (20 August 2004) Issue 4 . - pp. 911-925.
DOI: https://doi.org/10.1016/j.jmb.2004.06.047

Güthe, Sarah ; Kapinos, Larisa ; Möglich, Andreas ; Meier, Sebastian ; Grzesiek, Stephan ; Kiefhaber, Thomas:
Very fast folding and association of a trimerization domain from bacteriophage T4 fibritin.
In: Journal of Molecular Biology. Vol. 337 (2 April 2004) Issue 4 . - pp. 905-915.
DOI: https://doi.org/10.1016/j.jmb.2004.02.020

Gröger, Christian ; Möglich, Andreas ; Pons, Miguel ; Koch, Brigitte ; Hengstenberg, Wolfgang ; Kalbitzer, Hans Robert ; Brunner, Eike:
NMR-spectroscopic mapping of an engineered cavity in the I14A mutant of HPr from Staphylococcus carnosus using xenon.
In: Journal of the American Chemical Society. Vol. 125 (23 July 2003) Issue 29 . - pp. 8726-8727.
DOI: https://doi.org/10.1021/ja030113t

Möglich, Andreas ; Wenzler, Michael ; Kramer, Frank ; Glaser, Steffen J. ; Brunner, Eike:
Determination of residual dipolar couplings in homonuclear MOCCA-SIAM experiments.
In: Journal of Biomolecular NMR. Vol. 23 (July 2002) Issue 3 . - pp. 211-219.
DOI: https://doi.org/10.1023/A:1019841602348

Article in a book

Moffat, Keith ; Zhang, Feng ; Hahn, Klaus ; Möglich, Andreas:
The Biophysics and Engineering of Signaling Photoreceptors.
In: Hegemann, Peter ; Sigrist, Stephan (Hrsg.): Optogenetics. - Berlin : De Gruyter, 2013 . - pp. 7-20

Doctoral thesis

Volltext
Stabel, Robert:
Design neuer rotlichtaktivierter Enzyme zur Kontrolle von zyklischen Mononukleotiden.
Bayreuth , 2020 . - V, 132 p.
( Doctoral thesis, 2019 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00004689

Volltext
Ziegler, Thea:
Engineering and Characterization of RNA-binding LOV photoreceptors.
Bayreuth , 2020 . - 163 p.
( Doctoral thesis, 2019 , Universität Bayreuth, Fakultät für Biologie, Chemie und Geowissenschaften)
DOI: https://doi.org/10.15495/EPub_UBT_00004692

This list was generated on Wed Apr 1 01:29:23 2020 CEST.
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